WO2003065981A3 - Therapeutic use for lp229, in particular for wound healing - Google Patents

Therapeutic use for lp229, in particular for wound healing Download PDF

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Publication number
WO2003065981A3
WO2003065981A3 PCT/US2002/000487 US0200487W WO03065981A3 WO 2003065981 A3 WO2003065981 A3 WO 2003065981A3 US 0200487 W US0200487 W US 0200487W WO 03065981 A3 WO03065981 A3 WO 03065981A3
Authority
WO
WIPO (PCT)
Prior art keywords
diseases
wound healing
therapeutic use
skin
immunodeficiencies
Prior art date
Application number
PCT/US2002/000487
Other languages
French (fr)
Other versions
WO2003065981A2 (en
Inventor
Josef Georg Heuer
Kristine Kay Kirkly
Eric Wen Su
Original Assignee
Lilly Co Eli
Josef Georg Heuer
Kristine Kay Kirkly
Eric Wen Su
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Josef Georg Heuer, Kristine Kay Kirkly, Eric Wen Su filed Critical Lilly Co Eli
Priority to US10/250,959 priority Critical patent/US20040072745A1/en
Priority to AU2002365236A priority patent/AU2002365236A1/en
Priority to EP02805684A priority patent/EP1545591A2/en
Publication of WO2003065981A2 publication Critical patent/WO2003065981A2/en
Publication of WO2003065981A3 publication Critical patent/WO2003065981A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Methods of use are provided for the treatment or prevention of poor healing or chronic wounds, skin diseases, sepsis, inflammation, immunodeficiencies, autoimmune diseases, infectious diseases, allergic diseases, and malignancies, particularly those disorders associated with the skin, by administering an LP229 polypeptide, protein, or epitope-recognizing antibody thereof to a patient in need of such therapy.
PCT/US2002/000487 2001-01-18 2002-01-09 Therapeutic use for lp229, in particular for wound healing WO2003065981A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/250,959 US20040072745A1 (en) 2002-01-09 2002-01-09 Therapeutic methods of use for lp229
AU2002365236A AU2002365236A1 (en) 2001-01-18 2002-01-09 Therapeutic use for lp229, in particular for wound healing
EP02805684A EP1545591A2 (en) 2001-01-18 2002-01-09 Therapeutic use for lp229, in particular for wound healing

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26245801P 2001-01-18 2001-01-18
US60/262,458 2001-01-18
US32523301P 2001-09-27 2001-09-27
US60/325,233 2001-09-27

Publications (2)

Publication Number Publication Date
WO2003065981A2 WO2003065981A2 (en) 2003-08-14
WO2003065981A3 true WO2003065981A3 (en) 2005-04-07

Family

ID=27737161

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000487 WO2003065981A2 (en) 2001-01-18 2002-01-09 Therapeutic use for lp229, in particular for wound healing

Country Status (3)

Country Link
EP (1) EP1545591A2 (en)
AU (1) AU2002365236A1 (en)
WO (1) WO2003065981A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042201A2 (en) * 1999-01-11 2000-07-20 Incyte Pharmaceuticals, Inc. Human peptidases
WO2002026801A2 (en) * 2000-09-28 2002-04-04 Eli Lilly And Company Secreted proteins and their uses

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000042201A2 (en) * 1999-01-11 2000-07-20 Incyte Pharmaceuticals, Inc. Human peptidases
WO2002026801A2 (en) * 2000-09-28 2002-04-04 Eli Lilly And Company Secreted proteins and their uses

Also Published As

Publication number Publication date
WO2003065981A2 (en) 2003-08-14
AU2002365236A1 (en) 2003-09-02
EP1545591A2 (en) 2005-06-29
AU2002365236A8 (en) 2003-09-02

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