WO2003062808A3 - A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation - Google Patents

A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation Download PDF

Info

Publication number
WO2003062808A3
WO2003062808A3 PCT/IL2003/000048 IL0300048W WO03062808A3 WO 2003062808 A3 WO2003062808 A3 WO 2003062808A3 IL 0300048 W IL0300048 W IL 0300048W WO 03062808 A3 WO03062808 A3 WO 03062808A3
Authority
WO
WIPO (PCT)
Prior art keywords
value
temperature
receiving area
electrical signal
optical energy
Prior art date
Application number
PCT/IL2003/000048
Other languages
French (fr)
Other versions
WO2003062808A2 (en
Inventor
Nicolay Tszypco
Original Assignee
R S M D Ltd
Nicolay Tszypco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R S M D Ltd, Nicolay Tszypco filed Critical R S M D Ltd
Priority to AU2003207964A priority Critical patent/AU2003207964A1/en
Publication of WO2003062808A2 publication Critical patent/WO2003062808A2/en
Publication of WO2003062808A3 publication Critical patent/WO2003062808A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00—Investigating or analyzing materials by the use of thermal means
    • G01N25/72—Investigating presence of flaws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Radiation Pyrometers (AREA)

Abstract

Method and apparatus for the accurate detection of abnormal cells in an inspected live tissue. An optical receiver that comprises an active receiving area, such as a thermocouple, and has at least one pair of output contacts is provided. The optical receiver is capable of outputting a first electric signal that represents the optical energy received on the receiving area. at least a portion of the optical energy emitted from a surface being subjacent to the inspected live tissue and characterized by its emissivity factor, is received. The first electrical signal and the first value of the temperature of the receiving area are measured and the temperature of the receiving area is changed to a second value by applying a second electrical signal, representing a different level of optical energy to the pair. The temperature of the inspected live tissue and the emissivity factor are calculated using the first and second values and the first and second signals. The value of a third electrical signal, representing the actual value of the optical energy distributed within predetermined wavelength range, that corresponds to the calculated temperature, is measured by using the calculated temperature and the emissivity factor, and that value is compared to an expected value for the range and the calculated temperature. Indications regarding the presence of abnormal cells are obtained whenever the measured value of the third electrical signal essentially differs from the expected value.
PCT/IL2003/000048 2002-01-21 2003-01-20 A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation WO2003062808A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003207964A AU2003207964A1 (en) 2002-01-21 2003-01-20 A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL14773802A IL147738A0 (en) 2002-01-21 2002-01-21 A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation
IL147738 2002-01-21

Publications (2)

Publication Number Publication Date
WO2003062808A2 WO2003062808A2 (en) 2003-07-31
WO2003062808A3 true WO2003062808A3 (en) 2003-12-18

Family

ID=27590148

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2003/000048 WO2003062808A2 (en) 2002-01-21 2003-01-20 A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation

Country Status (3)

Country Link
AU (1) AU2003207964A1 (en)
IL (1) IL147738A0 (en)
WO (1) WO2003062808A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8227756B2 (en) * 2009-06-24 2012-07-24 Knowflame, Inc. Apparatus for flame discrimination utilizing long wavelength pass filters and related method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7901936A (en) * 1979-03-11 1980-09-15 Schlager Kenneth J Medical physiological diagnostic unit - has multiple sensors producing signals to digital memory unit dependent upon heat pattern of patient's body
EP0623811A1 (en) * 1993-05-03 1994-11-09 Universidade Do Minho Method of contactless measuring the surface temperature and/or emissivity of objects

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7901936A (en) * 1979-03-11 1980-09-15 Schlager Kenneth J Medical physiological diagnostic unit - has multiple sensors producing signals to digital memory unit dependent upon heat pattern of patient's body
EP0623811A1 (en) * 1993-05-03 1994-11-09 Universidade Do Minho Method of contactless measuring the surface temperature and/or emissivity of objects

Also Published As

Publication number Publication date
WO2003062808A2 (en) 2003-07-31
AU2003207964A1 (en) 2003-09-02
IL147738A0 (en) 2002-08-14

Similar Documents

Publication Publication Date Title
JP6846506B2 (en) Laser ranging system by time domain waveform matching and its method
Arnaud et al. Measurement of vertical profiles of snow specific surface area with a 1 cm resolution using infrared reflectance: instrument description and validation
US6693536B2 (en) Electromagnetic radiation monitor
EP1365218A3 (en) Wavelength meter for swept lasers
WO2004093663A3 (en) Wavefront calibration analyzer and methods
WO2007030700A3 (en) Power monitor for monitoring input optical power incident on avalanche photodiodes
WO2003092128A3 (en) Method to optimize generation of ultrasound using mathematical modeling for laser ultrasound inspection
KR100416764B1 (en) Non-invasive measuring apparatus of a living body and method thereof
CN107144356A (en) Non-refrigerated infrared focal plane probe array thermal Response Time Test System and method
CN108151799B (en) Multispectral multi-angle non-contact type pavement state monitoring device and method
CN110214267B (en) Portable device and method for estimating polymer parameters
JP2881201B2 (en) Method and apparatus for measuring sugar content of citrus fruit
WO2011064806A3 (en) Method and apparatus for measurements of luminous isotropic radiation as obtained by means of laser spectroscopy techniques, in particular for sub- micrometric particulate measurements
CN208076382U (en) Water body multi-wavelength optical attenuation coefficient measuring device
CN102822663A (en) Apparatus and method for detecting skin cancer using THz radiation
CA2037940A1 (en) System for temperature determination and calibration in a biomedical thermometer
CN206974900U (en) A kind of plant moisture content detection device based on terahertz light
CN109856081A (en) Portable kiwi fruit sugar fast non-destructive detection method and device
WO2003062808A3 (en) A method and apparatus for the diagnosis of unhealthy cells in live tissues, based on spectral analysis of their optical radiation
CN108414464A (en) Water body multi-wavelength optical attenuation coefficient measuring device and method
CN201892573U (en) Near-infrared radiation thermometer
CN102445325A (en) Device and method for measuring shade number of automatic darkening welding filter
SG160309A1 (en) Lithographic apparatus and humidity measurement system
CN111366967A (en) System and method for measuring irradiation dose rate of strong radiation field
CN116358698A (en) Laser output energy monitoring device and method

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP