WO2003061596A3 - Methods and reagents for generating chimeric serum peptide carri ers - Google Patents

Methods and reagents for generating chimeric serum peptide carri ers Download PDF

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Publication number
WO2003061596A3
WO2003061596A3 PCT/US2003/002085 US0302085W WO03061596A3 WO 2003061596 A3 WO2003061596 A3 WO 2003061596A3 US 0302085 W US0302085 W US 0302085W WO 03061596 A3 WO03061596 A3 WO 03061596A3
Authority
WO
WIPO (PCT)
Prior art keywords
reagents
methods
generating chimeric
serum peptide
carri ers
Prior art date
Application number
PCT/US2003/002085
Other languages
French (fr)
Other versions
WO2003061596A2 (en
Inventor
Jeno Gyuris
Aaron J Morris
Scott Wick
Original Assignee
Gpc Biotech Inc
Jeno Gyuris
Aaron J Morris
Scott Wick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gpc Biotech Inc, Jeno Gyuris, Aaron J Morris, Scott Wick filed Critical Gpc Biotech Inc
Priority to AU2003222199A priority Critical patent/AU2003222199A1/en
Publication of WO2003061596A2 publication Critical patent/WO2003061596A2/en
Publication of WO2003061596A3 publication Critical patent/WO2003061596A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates

Abstract

One aspect of the present invention is the synthesis of a binary method that combines variegated display libraries, e.g., in a 'display mode' and a 'secretion mode', to yield a method for the efficient isolation of chimeric serum peptides in having a desired biological activity.
PCT/US2003/002085 2002-01-23 2003-01-23 Methods and reagents for generating chimeric serum peptide carri ers WO2003061596A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003222199A AU2003222199A1 (en) 2002-01-23 2003-01-23 Methods and reagents for generating chimeric serum peptide carri ers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35122502P 2002-01-23 2002-01-23
US60/351,225 2002-01-23

Publications (2)

Publication Number Publication Date
WO2003061596A2 WO2003061596A2 (en) 2003-07-31
WO2003061596A3 true WO2003061596A3 (en) 2004-07-22

Family

ID=27613473

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/002085 WO2003061596A2 (en) 2002-01-23 2003-01-23 Methods and reagents for generating chimeric serum peptide carri ers

Country Status (2)

Country Link
AU (1) AU2003222199A1 (en)
WO (1) WO2003061596A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009052376A1 (en) 2007-10-18 2009-04-23 Musc Foundation For Research Development Methods for the diagnosis of genitourinary cancer
CN102517225A (en) * 2011-12-28 2012-06-27 浙江大学 Recombinant saccharymyces cerevisiae exhibiting amylase at surface as well as construction method and application

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503993A (en) * 1987-12-02 1996-04-02 The Green Cross Corporation Method of preparing foreign protein in yeast, recombinant DNA, transformant
US5648254A (en) * 1988-01-15 1997-07-15 Zymogenetics, Inc. Co-expression in eukaryotic cells
US6054312A (en) * 1997-08-29 2000-04-25 Selective Genetics, Inc. Receptor-mediated gene delivery using bacteriophage vectors
US6232081B1 (en) * 1997-10-16 2001-05-15 Baylor College Of Medicine Method for the detection of NF-κB regulatory factors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503993A (en) * 1987-12-02 1996-04-02 The Green Cross Corporation Method of preparing foreign protein in yeast, recombinant DNA, transformant
US5648254A (en) * 1988-01-15 1997-07-15 Zymogenetics, Inc. Co-expression in eukaryotic cells
US6054312A (en) * 1997-08-29 2000-04-25 Selective Genetics, Inc. Receptor-mediated gene delivery using bacteriophage vectors
US6232081B1 (en) * 1997-10-16 2001-05-15 Baylor College Of Medicine Method for the detection of NF-κB regulatory factors

Also Published As

Publication number Publication date
AU2003222199A1 (en) 2003-09-02
WO2003061596A2 (en) 2003-07-31

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