WO2003060121A3 - Compositions et procedes relatifs a des proteines et a des genes gastriques specifiques - Google Patents

Compositions et procedes relatifs a des proteines et a des genes gastriques specifiques Download PDF

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Publication number
WO2003060121A3
WO2003060121A3 PCT/US2002/041160 US0241160W WO03060121A3 WO 2003060121 A3 WO2003060121 A3 WO 2003060121A3 US 0241160 W US0241160 W US 0241160W WO 03060121 A3 WO03060121 A3 WO 03060121A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
gastric
compositions
antagonists
agonists
Prior art date
Application number
PCT/US2002/041160
Other languages
English (en)
Other versions
WO2003060121A2 (fr
WO2003060121A9 (fr
Inventor
Yongming Sun
Chenghua Liu
Original Assignee
Diadexus Inc
Yongming Sun
Chenghua Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diadexus Inc, Yongming Sun, Chenghua Liu filed Critical Diadexus Inc
Priority to AU2002359817A priority Critical patent/AU2002359817A1/en
Publication of WO2003060121A2 publication Critical patent/WO2003060121A2/fr
Publication of WO2003060121A3 publication Critical patent/WO2003060121A3/fr
Publication of WO2003060121A9 publication Critical patent/WO2003060121A9/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des molécules d'acide nucléique récemment identifiées et des polypeptides présents dans des cellules gastriques normales et néoplastiques, notamment des fragments, des variants et des dérivés d'acides nucléiques et de polypeptides. Cette invention concerne également des anticorps contre des polypeptides de l'invention, ainsi que des agonistes et des antagonistes de ces polypeptides. En outre, elle concerne des compositions contenant les molécules d'acide nucléique, les polypeptides, les anticorps, les agonistes et les antagonistes de l'invention et des procédés d'utilisation de ces compositions. On peut citer à titre d'exemple de ces utilisations l'identification, le diagnostic, la surveillance, la classification par stade, l'imagerie et le traitement du cancer gastrique et d'états pathologiques gastriques non cancéreux, l'identification de tissus gastriques, la surveillance et l'identification et/ou la conception d'agonistes et d'antagonistes des polypeptides de l'invention. Parmi ces utilisations, on compte également la thérapie génique, la production d'animaux et de cellules transgéniques, et la production de tissus gastriques génétiquement modifiés destinés au traitement et à la recherche.
PCT/US2002/041160 2001-12-21 2002-12-20 Compositions et procedes relatifs a des proteines et a des genes gastriques specifiques WO2003060121A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002359817A AU2002359817A1 (en) 2001-12-21 2002-12-20 Compositions and methods relating to gastric specific genes and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34313801P 2001-12-21 2001-12-21
US60/343,138 2001-12-21

Publications (3)

Publication Number Publication Date
WO2003060121A2 WO2003060121A2 (fr) 2003-07-24
WO2003060121A3 true WO2003060121A3 (fr) 2003-08-28
WO2003060121A9 WO2003060121A9 (fr) 2003-10-02

Family

ID=23344857

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/041160 WO2003060121A2 (fr) 2001-12-21 2002-12-20 Compositions et procedes relatifs a des proteines et a des genes gastriques specifiques

Country Status (2)

Country Link
AU (1) AU2002359817A1 (fr)
WO (1) WO2003060121A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130004318A (ko) 2010-03-03 2013-01-09 고쿠리츠 다이가쿠 호진 교토 다이가쿠 위암 검출용 마커 및 위암 검출 방법
WO2011108628A1 (fr) 2010-03-03 2011-09-09 東レ株式会社 Marqueur de cancer gastrique et procédé de détection de cancer gastrique

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024946A (en) * 1985-09-30 1991-06-18 Asahi Kasei Kabushiki Kaisha Human monoclonal antibody to antigen of gastric cancer and B-cell line for producing this antibody, method for preparing this B-cell line and antibody, antigen and method of preparation of this antigen
US5051355A (en) * 1986-07-15 1991-09-24 Kyowa Hakko Kogyo Co., Ltd. Anti-human gastric cancer monoclonal antibody
US6153390A (en) * 1992-10-13 2000-11-28 Vanderbilt University TagA gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
US6416961B1 (en) * 1997-03-18 2002-07-09 Biohit Oyj Diagnosis of early gastric cancer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024946A (en) * 1985-09-30 1991-06-18 Asahi Kasei Kabushiki Kaisha Human monoclonal antibody to antigen of gastric cancer and B-cell line for producing this antibody, method for preparing this B-cell line and antibody, antigen and method of preparation of this antigen
US5051355A (en) * 1986-07-15 1991-09-24 Kyowa Hakko Kogyo Co., Ltd. Anti-human gastric cancer monoclonal antibody
US6153390A (en) * 1992-10-13 2000-11-28 Vanderbilt University TagA gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma
US6416961B1 (en) * 1997-03-18 2002-07-09 Biohit Oyj Diagnosis of early gastric cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENEMBL [online] DOE JOINT GENOME INSTITUTE AND STANFORD HUMAN GENOME CENTER; 1 May 2001 (2001-05-01), "Homo sapiens chromosome 5 clone CTD-2353F22", XP002964894, Database accession no. (AC008957) *
DATABASE GENEMBL [online] DOE JOINT GENOME INSTITUTE AND STANFORD HUMAN GENOME CENTER; 18 April 2000 (2000-04-18), "Homo sapiens chromosome 5 clone CTD-2074B5", XP002964895, Database accession no. (AC010386) *
GIBCO B.R.L.: "Random primers DNA labeling system", LIFE TECHNOLOGIES, INC. (CATALOGUE AND REFERENCE GUIDE), 2000, pages 404, XP002965029 *

Also Published As

Publication number Publication date
WO2003060121A2 (fr) 2003-07-24
AU2002359817A1 (en) 2003-07-30
WO2003060121A9 (fr) 2003-10-02

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