WO2003059334A3 - Gemcitabine in the treatment of smallpox - Google Patents

Gemcitabine in the treatment of smallpox Download PDF

Info

Publication number
WO2003059334A3
WO2003059334A3 PCT/US2002/031570 US0231570W WO03059334A3 WO 2003059334 A3 WO2003059334 A3 WO 2003059334A3 US 0231570 W US0231570 W US 0231570W WO 03059334 A3 WO03059334 A3 WO 03059334A3
Authority
WO
WIPO (PCT)
Prior art keywords
gemcitabine
smallpox
treatment
patient
administering
Prior art date
Application number
PCT/US2002/031570
Other languages
French (fr)
Other versions
WO2003059334A2 (en
Inventor
John Irvin Glass
Original Assignee
Lilly Co Eli
John Irvin Glass
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, John Irvin Glass filed Critical Lilly Co Eli
Priority to AU2002365256A priority Critical patent/AU2002365256A1/en
Publication of WO2003059334A2 publication Critical patent/WO2003059334A2/en
Publication of WO2003059334A3 publication Critical patent/WO2003059334A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method of treating smallpox in a mammalian patient in need thereof comprising administering a therapeutically effective dose of gemcitabine to the patient.
PCT/US2002/031570 2001-10-25 2002-10-15 Gemcitabine in the treatment of smallpox WO2003059334A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002365256A AU2002365256A1 (en) 2001-10-25 2002-10-15 Gemcitabine in the treatment of smallpox

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35662301P 2001-10-25 2001-10-25
US60/356,623 2001-10-25

Publications (2)

Publication Number Publication Date
WO2003059334A2 WO2003059334A2 (en) 2003-07-24
WO2003059334A3 true WO2003059334A3 (en) 2003-10-30

Family

ID=23402228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/031570 WO2003059334A2 (en) 2001-10-25 2002-10-15 Gemcitabine in the treatment of smallpox

Country Status (2)

Country Link
AU (1) AU2002365256A1 (en)
WO (1) WO2003059334A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117982522A (en) * 2022-11-02 2024-05-07 河南真实生物科技有限公司 Pharmaceutical use of nucleoside compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808614A (en) * 1983-03-10 1989-02-28 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US4895937A (en) * 1982-01-05 1990-01-23 The Research Foundation Of State University Of New York 5-ioso-2-pyrimidinone nucleoside
US5837871A (en) * 1989-05-15 1998-11-17 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Nucleoside analogs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895937A (en) * 1982-01-05 1990-01-23 The Research Foundation Of State University Of New York 5-ioso-2-pyrimidinone nucleoside
US4808614A (en) * 1983-03-10 1989-02-28 Eli Lilly And Company Difluoro antivirals and intermediate therefor
US5837871A (en) * 1989-05-15 1998-11-17 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Nucleoside analogs

Also Published As

Publication number Publication date
AU2002365256A8 (en) 2003-07-30
AU2002365256A1 (en) 2003-07-30
WO2003059334A2 (en) 2003-07-24

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