WO2003057693A1 - 5-membered cyclic compounds - Google Patents

5-membered cyclic compounds Download PDF

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Publication number
WO2003057693A1
WO2003057693A1 PCT/JP2002/013725 JP0213725W WO03057693A1 WO 2003057693 A1 WO2003057693 A1 WO 2003057693A1 JP 0213725 W JP0213725 W JP 0213725W WO 03057693 A1 WO03057693 A1 WO 03057693A1
Authority
WO
WIPO (PCT)
Prior art keywords
membered cyclic
cyclic compounds
remedies
leukocytes
lymphocytes
Prior art date
Application number
PCT/JP2002/013725
Other languages
French (fr)
Japanese (ja)
Inventor
Norio Fujiwara
Fujio Antoku
Original Assignee
Sumitomo Pharmaceuticals Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co., Ltd. filed Critical Sumitomo Pharmaceuticals Co., Ltd.
Priority to AU2002361117A priority Critical patent/AU2002361117A1/en
Publication of WO2003057693A1 publication Critical patent/WO2003057693A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Remedies for inflammation having the following structure. Thus, drugs which inhibit the infiltration of leukocytes such as lymphocytes and are useful in treating various inflammations are provided.
PCT/JP2002/013725 2001-12-28 2002-12-26 5-membered cyclic compounds WO2003057693A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002361117A AU2002361117A1 (en) 2001-12-28 2002-12-26 5-membered cyclic compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001401397 2001-12-28
JP2001-401397 2001-12-28

Publications (1)

Publication Number Publication Date
WO2003057693A1 true WO2003057693A1 (en) 2003-07-17

Family

ID=19189769

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/013725 WO2003057693A1 (en) 2001-12-28 2002-12-26 5-membered cyclic compounds

Country Status (2)

Country Link
AU (1) AU2002361117A1 (en)
WO (1) WO2003057693A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006118268A1 (en) * 2005-04-28 2006-11-09 Dainippon Sumitomo Pharma Co., Ltd. Therapeutic agent for chronic obstructive pulmonary disease
EP2042492A1 (en) * 2007-09-26 2009-04-01 Bayer CropScience AG Novel Iminooxazole and Iminothiazole Compounds
WO2009131171A1 (en) 2008-04-25 2009-10-29 大日本住友製薬株式会社 Novel five-membered ring compound
WO2009131170A1 (en) 2008-04-25 2009-10-29 大日本住友製薬株式会社 Five-membered ring compound
JP2009538931A (en) * 2006-05-31 2009-11-12 アボット・ラボラトリーズ Thiazole compounds as cannabinoid receptor ligands and uses thereof
JP2009538933A (en) * 2006-05-31 2009-11-12 アボット・ラボラトリーズ Compounds and their use as cannabinoid receptor ligands

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000342A1 (en) * 1991-06-21 1993-01-07 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles with antiasthmatic and anti-inflammatory activities on the respiratory tract
WO2002002542A1 (en) * 2000-06-30 2002-01-10 Sumitomo Pharmaceuticals Company, Limited Five-membered-ring compound

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000342A1 (en) * 1991-06-21 1993-01-07 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles with antiasthmatic and anti-inflammatory activities on the respiratory tract
WO2002002542A1 (en) * 2000-06-30 2002-01-10 Sumitomo Pharmaceuticals Company, Limited Five-membered-ring compound

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ISLIP P.J. ET AL., J. MED. CHEM., vol. 117, no. 2, 1974, pages 207 - 209, XP002965254 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006118268A1 (en) * 2005-04-28 2006-11-09 Dainippon Sumitomo Pharma Co., Ltd. Therapeutic agent for chronic obstructive pulmonary disease
WO2006126581A1 (en) * 2005-04-28 2006-11-30 Dainippon Sumitomo Pharma Co., Ltd. Combination drug
US8012971B2 (en) 2005-04-28 2011-09-06 Dainippon Sumitomo Pharma Co., Ltd. Therapeutic agent for chronic obstructive pulmonary disease
AU2006241774B2 (en) * 2005-04-28 2011-09-15 Sumitomo Dainippon Pharma Co., Ltd. Therapeutic agent for chronic obstructive pulmonary disease
JP2009538931A (en) * 2006-05-31 2009-11-12 アボット・ラボラトリーズ Thiazole compounds as cannabinoid receptor ligands and uses thereof
JP2009538933A (en) * 2006-05-31 2009-11-12 アボット・ラボラトリーズ Compounds and their use as cannabinoid receptor ligands
EP2042492A1 (en) * 2007-09-26 2009-04-01 Bayer CropScience AG Novel Iminooxazole and Iminothiazole Compounds
WO2009040008A1 (en) * 2007-09-26 2009-04-02 Bayer Cropscience Ag Novel iminooxazole and iminothiazole compounds
WO2009131171A1 (en) 2008-04-25 2009-10-29 大日本住友製薬株式会社 Novel five-membered ring compound
WO2009131170A1 (en) 2008-04-25 2009-10-29 大日本住友製薬株式会社 Five-membered ring compound

Also Published As

Publication number Publication date
AU2002361117A1 (en) 2003-07-24

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