WO2003054208A2 - Method of modulating release of saccharides and uses thereof - Google Patents
Method of modulating release of saccharides and uses thereof Download PDFInfo
- Publication number
- WO2003054208A2 WO2003054208A2 PCT/CA2002/001917 CA0201917W WO03054208A2 WO 2003054208 A2 WO2003054208 A2 WO 2003054208A2 CA 0201917 W CA0201917 W CA 0201917W WO 03054208 A2 WO03054208 A2 WO 03054208A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- effect
- glucosamine
- saccharides
- monosaccharides
- oligomers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02787250A EP1455835A2 (en) | 2001-12-13 | 2002-12-12 | Method of modulating release of saccharides and uses thereof |
CA002507870A CA2507870A1 (en) | 2001-12-13 | 2002-12-12 | Method of modulating release of saccharides and uses thereof |
US10/498,002 US20050070500A1 (en) | 2001-12-13 | 2002-12-12 | Method of modulating release of saccharides and uses thereof |
AU2002351576A AU2002351576A1 (en) | 2001-12-13 | 2002-12-12 | Method of modulating release of saccharides and uses thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33933901P | 2001-12-13 | 2001-12-13 | |
US60/339,339 | 2001-12-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003054208A2 true WO2003054208A2 (en) | 2003-07-03 |
WO2003054208A3 WO2003054208A3 (en) | 2003-10-09 |
Family
ID=23328557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CA2002/001917 WO2003054208A2 (en) | 2001-12-13 | 2002-12-12 | Method of modulating release of saccharides and uses thereof |
Country Status (5)
Country | Link |
---|---|
US (1) | US20050070500A1 (en) |
EP (1) | EP1455835A2 (en) |
AU (1) | AU2002351576A1 (en) |
CA (1) | CA2507870A1 (en) |
WO (1) | WO2003054208A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200904340A (en) * | 2007-05-11 | 2009-02-01 | Mannatech Inc | Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same |
US20120157391A1 (en) * | 2009-07-16 | 2012-06-21 | Hirosaki University | Proteoglycan-containing material |
CN103429608B (en) | 2011-01-19 | 2016-08-03 | 国立大学法人弘前大学 | A large amount of preparation methoies of proteoglycan |
CA2869821C (en) | 2011-06-13 | 2018-06-19 | Rival, Societe En Commandite | N,n,n-trialkylaminopolymers, methods of their preparation and uses thereof |
KR102532825B1 (en) | 2016-03-30 | 2023-05-17 | 아유비스 리서치, 인코포레이티드 | Novel compositions and therapeutic methods |
DE202017107843U1 (en) | 2017-12-21 | 2019-03-25 | BÄ*RO GmbH & Co. KG | recessed light |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4532134A (en) * | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
WO1994022453A1 (en) * | 1993-03-31 | 1994-10-13 | Nutramax Laboratories, Inc. | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue |
WO1998025631A1 (en) * | 1996-12-13 | 1998-06-18 | Lescarden, Inc. | Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine |
WO1998048627A1 (en) * | 1997-04-29 | 1998-11-05 | Medicarb Ab | Teat dipping agent |
US5891861A (en) * | 1996-10-15 | 1999-04-06 | Platt; David | Composition and method for treating fungal disease in animals |
WO2001032188A1 (en) * | 1999-11-02 | 2001-05-10 | Shawn Paul Madere | Compositions of orally administered nutritional supplements to repair articular cartilage |
EP1127574A1 (en) * | 2000-02-22 | 2001-08-29 | Food Industry Research and Development Institute | Use of chitinous materials for inhibiting cellular nitric oxide production |
US6492350B2 (en) * | 2000-01-27 | 2002-12-10 | Jdc (Hawaii) Inc. | Chitin oligosaccharides and/or chitosan oligosaccharides for preventing or treating common cold or treating pain |
WO2003026677A1 (en) * | 2001-09-26 | 2003-04-03 | Primex Ehf. | Pharmaceutical composition comprising chito-oligomers |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4006224A (en) * | 1975-09-29 | 1977-02-01 | Lescarden Ltd. | Method and agent for treating inflammatory disorders of the gastrointestinal tract |
US4590067A (en) * | 1984-10-18 | 1986-05-20 | Peritain, Ltd. | Treatment for periodontal disease |
CA1261264A (en) * | 1984-11-29 | 1989-09-26 | Shigeo Suzuki | Immunopotentiating agents and method |
US5229374A (en) * | 1992-01-28 | 1993-07-20 | Burton Albert F | Method for treatment of lower gastrointestinal tract disorders |
DE69418322D1 (en) * | 1993-03-01 | 1999-06-10 | Glycan Pharm Inc | ANALOGS FOR SPECIFIC OLIGOSACCHARID-PROTEIN INTERACTIONS AND THEIR USE |
JP3393560B2 (en) * | 1993-12-29 | 2003-04-07 | 日本水産株式会社 | Calcium absorption promoting composition containing water-soluble chitosan and additive for promoting calcium absorption |
US5679344A (en) * | 1995-07-20 | 1997-10-21 | Susan K. Williams | Glucosamine composition and method |
US5981510A (en) * | 1997-04-15 | 1999-11-09 | Yaizu Suisankagaku Industry Co., Ltd. | Method for treating and improving diabetes |
-
2002
- 2002-12-12 CA CA002507870A patent/CA2507870A1/en not_active Abandoned
- 2002-12-12 AU AU2002351576A patent/AU2002351576A1/en not_active Abandoned
- 2002-12-12 US US10/498,002 patent/US20050070500A1/en not_active Abandoned
- 2002-12-12 WO PCT/CA2002/001917 patent/WO2003054208A2/en not_active Application Discontinuation
- 2002-12-12 EP EP02787250A patent/EP1455835A2/en not_active Ceased
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4532134A (en) * | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
WO1994022453A1 (en) * | 1993-03-31 | 1994-10-13 | Nutramax Laboratories, Inc. | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue |
US5891861A (en) * | 1996-10-15 | 1999-04-06 | Platt; David | Composition and method for treating fungal disease in animals |
WO1998025631A1 (en) * | 1996-12-13 | 1998-06-18 | Lescarden, Inc. | Treatment of osteoarthritis by administering poly-n-acetyl-d-glucosamine |
WO1998048627A1 (en) * | 1997-04-29 | 1998-11-05 | Medicarb Ab | Teat dipping agent |
WO2001032188A1 (en) * | 1999-11-02 | 2001-05-10 | Shawn Paul Madere | Compositions of orally administered nutritional supplements to repair articular cartilage |
US6492350B2 (en) * | 2000-01-27 | 2002-12-10 | Jdc (Hawaii) Inc. | Chitin oligosaccharides and/or chitosan oligosaccharides for preventing or treating common cold or treating pain |
EP1127574A1 (en) * | 2000-02-22 | 2001-08-29 | Food Industry Research and Development Institute | Use of chitinous materials for inhibiting cellular nitric oxide production |
WO2003026677A1 (en) * | 2001-09-26 | 2003-04-03 | Primex Ehf. | Pharmaceutical composition comprising chito-oligomers |
Non-Patent Citations (2)
Title |
---|
ILLUM L: "CHITOSAN AND ITS USE AS A PHARAMACEUTICAL EXCIPIENT" PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 15, no. 9, September 1998 (1998-09), pages 1326-1331, XP008005983 ISSN: 0724-8741 * |
SKAUGRUD O: "CHITOSAN-NEW BIOPOLYMER FOR COSMETICS & DRUGS" DRUG AND COSMETIC INDUSTRY, XX, XX, vol. 148, 1 May 1991 (1991-05-01), page 24,26,30 XP000564874 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003054208A3 (en) | 2003-10-09 |
AU2002351576A1 (en) | 2003-07-09 |
AU2002351576A8 (en) | 2003-07-09 |
EP1455835A2 (en) | 2004-09-15 |
CA2507870A1 (en) | 2003-07-03 |
US20050070500A1 (en) | 2005-03-31 |
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