WO2003054004A3 - Secreted proteins - Google Patents

Secreted proteins Download PDF

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Publication number
WO2003054004A3
WO2003054004A3 PCT/GB2002/005858 GB0205858W WO03054004A3 WO 2003054004 A3 WO2003054004 A3 WO 2003054004A3 GB 0205858 W GB0205858 W GB 0205858W WO 03054004 A3 WO03054004 A3 WO 03054004A3
Authority
WO
WIPO (PCT)
Prior art keywords
secreted proteins
secreted protein
protein molecules
insp031
insp030
Prior art date
Application number
PCT/GB2002/005858
Other languages
French (fr)
Other versions
WO2003054004A2 (en
Inventor
Tania Maria Rodrigues
Richard Joseph Fagan
Christopher Benjamin Phelps
Christine Power
Melanie Yorke
Mark Ibberson
Original Assignee
Ares Trading Sa
Tania Maria Rodrigues
Richard Joseph Fagan
Christopher Benjamin Phelps
Christine Power
Melanie Yorke
Mark Ibberson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa, Tania Maria Rodrigues, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Melanie Yorke, Mark Ibberson filed Critical Ares Trading Sa
Priority to AU2002361452A priority Critical patent/AU2002361452A1/en
Publication of WO2003054004A2 publication Critical patent/WO2003054004A2/en
Publication of WO2003054004A3 publication Critical patent/WO2003054004A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Hall/Mr Elements (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention is based on the discovery that the INSP030 and INSP031 proteins function as secreted protein molecules and, moreover, as secreted protein molecules of the IGFBP class.
PCT/GB2002/005858 2001-12-20 2002-12-20 Secreted proteins WO2003054004A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002361452A AU2002361452A1 (en) 2001-12-20 2002-12-20 Secreted proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0130557.2 2001-12-20
GBGB0130557.2A GB0130557D0 (en) 2001-12-20 2001-12-20 Proteins

Publications (2)

Publication Number Publication Date
WO2003054004A2 WO2003054004A2 (en) 2003-07-03
WO2003054004A3 true WO2003054004A3 (en) 2003-11-27

Family

ID=9928092

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/005858 WO2003054004A2 (en) 2001-12-20 2002-12-20 Secreted proteins

Country Status (3)

Country Link
AU (1) AU2002361452A1 (en)
GB (1) GB0130557D0 (en)
WO (1) WO2003054004A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010517023A (en) 2007-01-25 2010-05-20 エフ．ホフマン−ラ ロシュ アーゲー Use of IGFBP-7 in the assessment of heart failure
CN102187220B (en) 2008-08-28 2015-08-19 阿斯图特医药公司 For the method and composition of diagnosis and prognosis injury of kidney and kidney failure
JP5947544B2 (en) 2008-08-29 2016-07-06 アスチュート メディカル，インコーポレイテッド Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2740788C (en) 2008-10-21 2023-03-14 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2009313189B2 (en) 2008-11-10 2014-10-23 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2462440B1 (en) 2009-08-07 2017-05-17 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2013510322A (en) 2009-11-07 2013-03-21 アスチュート メディカル，インコーポレイテッド Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN104698161A (en) 2009-12-20 2015-06-10 阿斯图特医药公司 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN102791885B (en) * 2010-02-05 2015-09-09 阿斯图特医药公司 For the method and composition of the diagnosis and prognostic of injury of the kidney and renal failure
US9029093B2 (en) 2010-02-26 2015-05-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3339859A1 (en) 2010-06-23 2018-06-27 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2011269775B2 (en) 2010-06-23 2015-01-15 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2013086359A1 (en) 2011-12-08 2013-06-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3361255B1 (en) 2013-01-17 2020-03-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US10300108B2 (en) 2013-12-03 2019-05-28 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2016164854A1 (en) 2015-04-09 2016-10-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA3026502A1 (en) 2016-06-06 2017-12-14 Astute Medical, Inc. Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 4 October 1999 (1999-10-04), XP002246307, retrieved from EBI Database accession no. AC011212 *
DATABASE GENSEQ [online] 7 November 2001 (2001-11-07), XP002246306, retrieved from EBI Database accession no. AAS28551 *

Also Published As

Publication number Publication date
AU2002361452A8 (en) 2003-07-09
WO2003054004A2 (en) 2003-07-03
AU2002361452A1 (en) 2003-07-09
GB0130557D0 (en) 2002-02-06

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