WO2003051795A3 - Resin-bonded isonitriles - Google Patents

Resin-bonded isonitriles Download PDF

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Publication number
WO2003051795A3
WO2003051795A3 PCT/EP2002/014386 EP0214386W WO03051795A3 WO 2003051795 A3 WO2003051795 A3 WO 2003051795A3 EP 0214386 W EP0214386 W EP 0214386W WO 03051795 A3 WO03051795 A3 WO 03051795A3
Authority
WO
WIPO (PCT)
Prior art keywords
bonded
isonitriles
resin
preparing
methods
Prior art date
Application number
PCT/EP2002/014386
Other languages
German (de)
French (fr)
Other versions
WO2003051795A2 (en
Inventor
Bernd Henkel
Original Assignee
Morphochem Ag
Bernd Henkel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphochem Ag, Bernd Henkel filed Critical Morphochem Ag
Priority to AU2002358734A priority Critical patent/AU2002358734A1/en
Publication of WO2003051795A2 publication Critical patent/WO2003051795A2/en
Publication of WO2003051795A3 publication Critical patent/WO2003051795A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

The invention relates to novel polymer-bonded isocyanide derivatives of general formula (I), to methods for preparing them, and to their use for synthesizing heterocycles and substance libraries.
PCT/EP2002/014386 2001-12-18 2002-12-17 Resin-bonded isonitriles WO2003051795A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002358734A AU2002358734A1 (en) 2001-12-18 2002-12-17 Resin-bonded isonitriles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10162134.5 2001-12-18
DE2001162134 DE10162134A1 (en) 2001-12-18 2001-12-18 Resin-bound isonitriles

Publications (2)

Publication Number Publication Date
WO2003051795A2 WO2003051795A2 (en) 2003-06-26
WO2003051795A3 true WO2003051795A3 (en) 2003-12-18

Family

ID=7709648

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/014386 WO2003051795A2 (en) 2001-12-18 2002-12-17 Resin-bonded isonitriles

Country Status (3)

Country Link
AU (1) AU2002358734A1 (en)
DE (1) DE10162134A1 (en)
WO (1) WO2003051795A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10230872A1 (en) * 2002-07-09 2004-01-22 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Process for the preparation of substituted thiazol-2-ylmethyl esters
MXPA06014307A (en) * 2004-06-08 2007-03-12 Alza Corp Preparation of macromolecular conjugates by four-component condensation reaction.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037983A1 (en) * 1999-11-22 2001-05-31 Astrazeneca Ab New functionalized polymeric reagents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001037983A1 (en) * 1999-11-22 2001-05-31 Astrazeneca Ab New functionalized polymeric reagents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN J J ET AL: "Universal Rink-isonitrile resin: application for the traceless synthesis of 3-acylamino imidazo[1,2-a]pyridines", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 42, no. 12, 18 March 2001 (2001-03-18), pages 2269 - 2271, XP004229899, ISSN: 0040-4039 *
SCHÖLLKOPF, U ET AL: "Notiz über beta-dimethylamino-alpha-isocyanacrylsäureester und ihre Verwendung in der Heterocyclenchemie", LIEBIGS ANNALEN DER CHEMIE., 1979, VERLAG CHEMIE GMBH. WEINHEIM., DE, pages 1444 - 1446, XP002242440, ISSN: 0170-2041 *

Also Published As

Publication number Publication date
DE10162134A1 (en) 2003-07-10
WO2003051795A2 (en) 2003-06-26
AU2002358734A1 (en) 2003-06-30
AU2002358734A8 (en) 2003-06-30

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