WO2003048357A1 - Procede d'activation de proteine - Google Patents

Procede d'activation de proteine Download PDF

Info

Publication number
WO2003048357A1
WO2003048357A1 PCT/JP2002/012701 JP0212701W WO03048357A1 WO 2003048357 A1 WO2003048357 A1 WO 2003048357A1 JP 0212701 W JP0212701 W JP 0212701W WO 03048357 A1 WO03048357 A1 WO 03048357A1
Authority
WO
WIPO (PCT)
Prior art keywords
protein
serum
free
activating protein
producing
Prior art date
Application number
PCT/JP2002/012701
Other languages
English (en)
French (fr)
Inventor
Takaharu Kouno
Yasuhiko Katsumura
Original Assignee
Mitsubishi Pharma Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Pharma Corporation filed Critical Mitsubishi Pharma Corporation
Priority to EP02788712A priority Critical patent/EP1452597A4/en
Priority to JP2003549535A priority patent/JP4249028B2/ja
Priority to AU2002354363A priority patent/AU2002354363A1/en
Priority to CA002468971A priority patent/CA2468971A1/en
Priority to US10/497,516 priority patent/US20050123532A1/en
Publication of WO2003048357A1 publication Critical patent/WO2003048357A1/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PCT/JP2002/012701 2001-12-04 2002-12-04 Procede d'activation de proteine WO2003048357A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP02788712A EP1452597A4 (en) 2001-12-04 2002-12-04 PROTEIN ACTIVATION METHOD
JP2003549535A JP4249028B2 (ja) 2001-12-04 2002-12-04 蛋白質の活性化方法
AU2002354363A AU2002354363A1 (en) 2001-12-04 2002-12-04 Method of activating protein
CA002468971A CA2468971A1 (en) 2001-12-04 2002-12-04 Method of activating protein
US10/497,516 US20050123532A1 (en) 2001-12-04 2002-12-04 Method of activating protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001370541 2001-12-04
JP2001-370541 2001-12-04

Publications (1)

Publication Number Publication Date
WO2003048357A1 true WO2003048357A1 (fr) 2003-06-12

Family

ID=19179747

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/012701 WO2003048357A1 (fr) 2001-12-04 2002-12-04 Procede d'activation de proteine

Country Status (6)

Country Link
US (1) US20050123532A1 (ja)
EP (1) EP1452597A4 (ja)
JP (1) JP4249028B2 (ja)
AU (1) AU2002354363A1 (ja)
CA (1) CA2468971A1 (ja)
WO (1) WO2003048357A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056872A1 (ja) * 2002-12-20 2004-07-08 Mitsubishi Pharma Corporation タンパク質のチオール基を保護する方法
JP2008544758A (ja) * 2005-07-05 2008-12-11 アレス トレーディング ソシエテ アノニム 組み換えゴナドトロピンの製造のための無血清培地

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2733466C2 (ru) 2009-07-28 2020-10-01 Шайр Хьюман Дженетик Терапиз Композиции и способы для лечения болезни гоше
AR103172A1 (es) 2014-12-22 2017-04-19 Novartis Ag Reducción selectiva de residuos de cisteina en anticuerpos il-17
PT3334760T (pt) 2015-08-12 2021-04-23 Pfizer Cisteínas de anticorpos com cap e sem cap e utilizações das mesmas na conjugação de anticorpo-fármaco

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315782A2 (de) * 1987-10-13 1989-05-17 Dr. Karl Thomae GmbH Verfahren zur Herstellung von Proteinen
WO1992014749A1 (en) * 1991-02-13 1992-09-03 The Board Of Trustees Of The Leland Stanford Junior University Thyroid-derived chondrocyte-stimulating factor
EP0520499A1 (en) * 1991-06-28 1992-12-30 Mitsubishi Chemical Corporation Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
JPH0870859A (ja) * 1994-06-27 1996-03-19 Takeda Chem Ind Ltd 動物細胞培養用の無血清培地、および生理活性ペプチドまたは蛋白質の製造法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511503A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
EP0641385B1 (en) * 1990-10-25 2002-12-18 The Trustees of Columbia University in the City of New York Development of dna probes and immunological reagents of human tumor associated antigens
JP3220180B2 (ja) * 1991-05-23 2001-10-22 三菱化学株式会社 薬剤含有タンパク質結合リポソーム
US5840687A (en) * 1995-02-02 1998-11-24 Schering Aktiengesellschaft Modified ligands for receptor tyrosine kinases
EP0799892A3 (en) * 1996-04-05 1998-08-12 Takeda Chemical Industries, Ltd. Calpain, its production and use
BR9709569B1 (pt) * 1996-06-11 2010-05-18 processo para ativação de proteìna desnaturada.
EP1127148B1 (en) * 1998-10-31 2012-08-08 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Variants of humanized anti-carcinoma monoclonal antibody cc49
DK1200561T3 (da) * 1999-08-05 2006-10-16 Baxter Ag Rekombinant stabil celleklon, dens fremstilling og anvendelse
EP1410806A4 (en) * 2001-07-25 2007-07-04 Mitsubishi Pharma Corp REMEDIES FOR BREAST CANCER

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0315782A2 (de) * 1987-10-13 1989-05-17 Dr. Karl Thomae GmbH Verfahren zur Herstellung von Proteinen
WO1992014749A1 (en) * 1991-02-13 1992-09-03 The Board Of Trustees Of The Leland Stanford Junior University Thyroid-derived chondrocyte-stimulating factor
EP0520499A1 (en) * 1991-06-28 1992-12-30 Mitsubishi Chemical Corporation Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
JPH0870859A (ja) * 1994-06-27 1996-03-19 Takeda Chem Ind Ltd 動物細胞培養用の無血清培地、および生理活性ペプチドまたは蛋白質の製造法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1452597A4 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004056872A1 (ja) * 2002-12-20 2004-07-08 Mitsubishi Pharma Corporation タンパク質のチオール基を保護する方法
EP1574521A1 (en) * 2002-12-20 2005-09-14 Mitsubishi Pharma Corporation Method of protecting thiol group of protein
EP1574521A4 (en) * 2002-12-20 2006-04-12 Mitsubishi Pharma Corp METHOD FOR PROTECTING THE THIOL GROUP OF A PROTEIN
JP2008544758A (ja) * 2005-07-05 2008-12-11 アレス トレーディング ソシエテ アノニム 組み換えゴナドトロピンの製造のための無血清培地

Also Published As

Publication number Publication date
CA2468971A1 (en) 2003-06-12
JPWO2003048357A1 (ja) 2005-04-14
EP1452597A4 (en) 2006-09-20
US20050123532A1 (en) 2005-06-09
AU2002354363A1 (en) 2003-06-17
JP4249028B2 (ja) 2009-04-02
EP1452597A1 (en) 2004-09-01

Similar Documents

Publication Publication Date Title
EP2270031A3 (en) Heterologous expression of neisserial proteins
EP2039762A3 (en) Nitralases
WO2005042695A3 (en) Lipoparticles comprising proteins, methods of making, and using the same
AU2002303933A1 (en) Fluidic valves, agitators, and pumps and methods thereof
AU2002236300A1 (en) Novel protein, gene encoding the same and method of using the same
WO2003012114A3 (en) Methods of rna and protein synthesis
WO2001090147A3 (en) Long wavelength engineered fluorescent proteins
WO2003048357A1 (fr) Procede d'activation de proteine
WO2002090300A8 (en) Nucleic acids and proteins with thioredoxin reductase activity
AU2002368056A1 (en) Novel pla2 enzyme, it's antibody, enzyme inhibitor and use and the preparation methods thereof
WO2001094627A3 (en) Assay techniques based on growth stage dependent expression in c. elegans
AU2002365269A1 (en) Mut-il-18 or mut-il-18r proteins, antibodies, compositions, methods and uses
WO2001068846A3 (en) Transcription activator of the cited family
AU2003247537A1 (en) Chd5 encoding nucleic acids, polypeptides, antibodies and methods of use thereof
WO2003091447A3 (en) D1-1 nucleic acids, polypeptides and related methods
AU2002306860A1 (en) Isolated human nadph oxidase, nucleic acid molecules encoding said proteins, and uses thereof
WO2003031642A3 (en) lovE VARIANT REGULATOR MOLECULES
AU2002246585A1 (en) Plant promoters, and methods of use
AU2002258630A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
WO2003025134A3 (en) mcFP ENCODING NUCLEIC ACIDS, POLYPEPTIDES, ANTIBODIES AND METHODS OF USE THEREOF
AU2002258617A1 (en) Isolated human enzyme proteins, nucleic acid molecules encoding human enzyme proteins, and uses thereof
WO2004043981A3 (en) Nucleic acids and proteins with thioredoxin reductase activity
AU2002254438A1 (en) Isolated human enzyme proteins, nucleic acid molecules encoding human enzyme proteins, and uses thereof
AU2002356494A1 (en) Isolated human enzyme proteins, nucleic acid molecules encoding human enzyme proteins, and uses thereof
AU2002314215A1 (en) Enzymatic method of producing 4-0-beta-D galactopyranosyl-D-xylose, 4-0-beta-D-galactopyranosyl-D-xylose obtained using said method, compositions containing same and the use thereof in evaluating intestinal lactase

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003549535

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002788712

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2468971

Country of ref document: CA

WWP Wipo information: published in national office

Ref document number: 2002788712

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 10497516

Country of ref document: US