WO2003048185A3 - Angiopioetin related factors - Google Patents

Angiopioetin related factors Download PDF

Info

Publication number
WO2003048185A3
WO2003048185A3 PCT/US2002/037660 US0237660W WO03048185A3 WO 2003048185 A3 WO2003048185 A3 WO 2003048185A3 US 0237660 W US0237660 W US 0237660W WO 03048185 A3 WO03048185 A3 WO 03048185A3
Authority
WO
WIPO (PCT)
Prior art keywords
wild
domain
amino acid
acid sequence
fusion proteins
Prior art date
Application number
PCT/US2002/037660
Other languages
French (fr)
Other versions
WO2003048185A2 (en
Inventor
Paul D Kessler
Imre Kovesdi
Original Assignee
Genvec Inc
Paul D Kessler
Imre Kovesdi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genvec Inc, Paul D Kessler, Imre Kovesdi filed Critical Genvec Inc
Priority to AU2002359464A priority Critical patent/AU2002359464A1/en
Publication of WO2003048185A2 publication Critical patent/WO2003048185A2/en
Publication of WO2003048185A3 publication Critical patent/WO2003048185A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The invention provides fusion proteins comprising a fibrinogen-like domain comprising an amino acid sequence identical or homologous to the amino acid sequence of the fibrinogen-like domain of a first wild-type angiopoietin-related factor and a coiled-coil domain comprising an amino acid sequence identical or homologous to the coiled-coil domain of a second wild-type angiopoietin-related factor, where the first and second wild-type angiopoietin related factors are different. The invention further provides polynucleotides encoding such fusion proteins, vectors comprising such polynucleotides, and methods of making and administering such fusion proteins, polynucleotides, and vectors.
PCT/US2002/037660 2001-11-30 2002-11-21 Angiopioetin related factors WO2003048185A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002359464A AU2002359464A1 (en) 2001-11-30 2002-11-21 Angiopioetin related factors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33448801P 2001-11-30 2001-11-30
US60/334,488 2001-11-30

Publications (2)

Publication Number Publication Date
WO2003048185A2 WO2003048185A2 (en) 2003-06-12
WO2003048185A3 true WO2003048185A3 (en) 2004-06-24

Family

ID=23307442

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/037660 WO2003048185A2 (en) 2001-11-30 2002-11-21 Angiopioetin related factors

Country Status (2)

Country Link
AU (1) AU2002359464A1 (en)
WO (1) WO2003048185A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050123925A1 (en) 2002-11-15 2005-06-09 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7081443B2 (en) 2002-05-21 2006-07-25 Korea Advanced Institutes Of Science And Technology (Kaist) Chimeric comp-ang1 molecule
US7371384B2 (en) 2004-07-20 2008-05-13 Genentech, Inc. Compositions and methods of using angiopoietin-like 4 protein antibody
US8604185B2 (en) 2004-07-20 2013-12-10 Genentech, Inc. Inhibitors of angiopoietin-like 4 protein, combinations, and their use
NZ552956A (en) 2004-07-20 2010-03-26 Genentech Inc Inhibitors of angiopoietin-like 4 protein (ANGPTL4), combinations, and their use for treating cancer
EP2457578B1 (en) * 2004-09-28 2015-08-19 Aprogen, Inc. Chimeric molecule comprising angiopoietin-1 and a coiled-coil domain for use in treating penile erectile dysfunction
EP1835929B8 (en) 2005-01-06 2016-07-27 Novo Nordisk A/S Anti-kir combination treatments and methods
US7829673B2 (en) 2005-03-23 2010-11-09 Genmab A/S Antibodies against CD38 for treatment of multiple myeloma
SG10201603962TA (en) 2011-05-25 2016-07-28 Innate Pharma Sa Anti-kir antibodies for the treatment of inflammatory disorders
WO2013154744A1 (en) * 2012-04-13 2013-10-17 Cornell University Development of a highly efficient second generation nicotine-conjugate vaccine to treat nicotine addiction
US9540428B2 (en) * 2012-07-03 2017-01-10 Ecole Polytechnique Federale De Lausanne (Epfl) Extracellular matrix heparin-binding domains
GB202108761D0 (en) * 2021-06-18 2021-08-04 Ikarovec Ltd Ocular disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6074873A (en) * 1997-09-19 2000-06-13 Genentech, Inc. Nucleic acids encoding NL-3
US6265564B1 (en) * 1996-08-02 2001-07-24 Regeneron Pharmaceuticals, Inc. Expressed ligand-vascular intercellular signalling molecule
US6406693B1 (en) * 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265564B1 (en) * 1996-08-02 2001-07-24 Regeneron Pharmaceuticals, Inc. Expressed ligand-vascular intercellular signalling molecule
US20030092891A1 (en) * 1996-08-02 2003-05-15 Samuel Davis Expressed ligand - vascular intercellular signalling molecule
US6074873A (en) * 1997-09-19 2000-06-13 Genentech, Inc. Nucleic acids encoding NL-3
US6406693B1 (en) * 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids

Also Published As

Publication number Publication date
AU2002359464A1 (en) 2003-06-17
AU2002359464A8 (en) 2003-06-17
WO2003048185A2 (en) 2003-06-12

Similar Documents

Publication Publication Date Title
WO2003048185A3 (en) Angiopioetin related factors
WO2002059306A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002040683A3 (en) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002077190A8 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002072765A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2003006485A3 (en) Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
WO2003033675A3 (en) Identification of binding partners for specific proteins
WO2002046406A3 (en) Human transporter proteins, nucleic acid molecules encoding them,and uses thereof
WO2001081412A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding the same, and uses thereof
WO2002068648A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these humans ras-like proteins, and uses thereof
WO2003074675A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002074976A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002079494A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002024910A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002057310A3 (en) Human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002081654A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002072831A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002061088A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002079386A3 (en) Isolated human ras-like proteins, nucleic and acid molecules encoding these human ras-like proteins, and uses thereof
WO2002079407A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002022678A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
WO2002062849A3 (en) Isolated human ras-like proteins, nucleic acid molecules encoding them, and uses thereof
WO2002074973A8 (en) Isolated human ras-like proteins, nucleic acid molecules encoding these human ras-like proteins, and uses thereof
WO2002068468A3 (en) Isolated human tumor supressor proteins, nucleic acid molecules encoding these human tumor supressor proteins, and uses thereof
WO2002079227A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP