WO2003028739A3 - Composition for preventing or treating hyperlipidemia or hyperglycemia comprising a polymer or its salt - Google Patents

Composition for preventing or treating hyperlipidemia or hyperglycemia comprising a polymer or its salt Download PDF

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Publication number
WO2003028739A3
WO2003028739A3 PCT/JP2002/009181 JP0209181W WO03028739A3 WO 2003028739 A3 WO2003028739 A3 WO 2003028739A3 JP 0209181 W JP0209181 W JP 0209181W WO 03028739 A3 WO03028739 A3 WO 03028739A3
Authority
WO
WIPO (PCT)
Prior art keywords
salt
hyperglycemia
polymer
preventing
composition
Prior art date
Application number
PCT/JP2002/009181
Other languages
French (fr)
Other versions
WO2003028739A2 (en
Inventor
Osamu Nakayama
Yuko Muramatsu
Yoshimitsu Nakajima
Akira Yamada
Hideo Sawada
Original Assignee
Fujisawa Pharmaceutical Co
Osamu Nakayama
Yuko Muramatsu
Yoshimitsu Nakajima
Akira Yamada
Hideo Sawada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2002950181A external-priority patent/AU2002950181A0/en
Application filed by Fujisawa Pharmaceutical Co, Osamu Nakayama, Yuko Muramatsu, Yoshimitsu Nakajima, Akira Yamada, Hideo Sawada filed Critical Fujisawa Pharmaceutical Co
Priority to AU2002326170A priority Critical patent/AU2002326170A1/en
Publication of WO2003028739A2 publication Critical patent/WO2003028739A2/en
Publication of WO2003028739A3 publication Critical patent/WO2003028739A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A61K31/75—Polymers of hydrocarbons of ethene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/755—Polymers containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/795—Polymers containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

A composition for preventing or treating hyperlipidemia (e.g., hypercholesterolemia, hypertriglyceridemia) or hyperglycemia comprising a polymer or its salt which is obtainable by polymerization of a monomer of the formula (I) or its salt in the presence of a radical initiator, or by polymerization of a monomer of the formula (I) or its salt with a monomer of the formula (II) or its salt in a molar ratio of (I) : (II) being 1:0.1 to 1:25 in the presence of a radical initiator wherein R1, R2, R3, R4 are as defined in the description as an active ingredient, in association with a pharmaceutically acceptable, non-toxic carrier or excipient.
PCT/JP2002/009181 2001-09-13 2002-09-09 Composition for preventing or treating hyperlipidemia or hyperglycemia comprising a polymer or its salt WO2003028739A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002326170A AU2002326170A1 (en) 2001-09-13 2002-09-09 Composition for preventing or treating hyperlipidemia or hyperglycemia comprising a polymer or its salt

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPR767101 2001-09-13
AUPR7671 2001-09-13
AU2002950181A AU2002950181A0 (en) 2002-07-15 2002-07-15 Composition for preventing or treating hyperlipemia, hypercholesterolemina or hyperglycemia
AU2002950181 2002-07-15

Publications (2)

Publication Number Publication Date
WO2003028739A2 WO2003028739A2 (en) 2003-04-10
WO2003028739A3 true WO2003028739A3 (en) 2003-09-04

Family

ID=25646799

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/009181 WO2003028739A2 (en) 2001-09-13 2002-09-09 Composition for preventing or treating hyperlipidemia or hyperglycemia comprising a polymer or its salt

Country Status (3)

Country Link
AR (1) AR036512A1 (en)
AU (1) AU2002326170A1 (en)
WO (1) WO2003028739A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5720103B2 (en) * 2010-03-18 2015-05-20 東レ株式会社 Silicone hydrogels, ophthalmic lenses and contact lenses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
WO2000000526A1 (en) * 1998-06-30 2000-01-06 Linkies, Adolf, Heinz Novel method for producing cross-linked vinyl polymers based on quaternary ammonium groups exhibiting a bile acid adsorbent effect

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
WO2000000526A1 (en) * 1998-06-30 2000-01-06 Linkies, Adolf, Heinz Novel method for producing cross-linked vinyl polymers based on quaternary ammonium groups exhibiting a bile acid adsorbent effect

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WONG N N: "Colesevelam: a new bile acid sequestrant.", HEART DISEASE. UNITED STATES 2001 JAN-FEB, vol. 3, no. 1, January 2001 (2001-01-01), pages 63 - 70, XP009003564, ISSN: 1521-737X *

Also Published As

Publication number Publication date
WO2003028739A2 (en) 2003-04-10
AU2002326170A1 (en) 2003-04-14
AR036512A1 (en) 2004-09-15

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