WO2003026555A3 - Dispositif osmotique flottant pour l'administration de medicaments a liberation regulee - Google Patents

Dispositif osmotique flottant pour l'administration de medicaments a liberation regulee Download PDF

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Publication number
WO2003026555A3
WO2003026555A3 PCT/IN2002/000124 IN0200124W WO03026555A3 WO 2003026555 A3 WO2003026555 A3 WO 2003026555A3 IN 0200124 W IN0200124 W IN 0200124W WO 03026555 A3 WO03026555 A3 WO 03026555A3
Authority
WO
WIPO (PCT)
Prior art keywords
active agent
osmotic device
floating
floating osmotic
drug delivery
Prior art date
Application number
PCT/IN2002/000124
Other languages
English (en)
Other versions
WO2003026555A2 (fr
Inventor
Bharat Pravinchandra Mehta
Madhukant Mansukhlal Doshi
Milind Dattatraya Joshi
Original Assignee
Jb Chemicals & Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jb Chemicals & Pharmaceuticals filed Critical Jb Chemicals & Pharmaceuticals
Priority to AU2002319893A priority Critical patent/AU2002319893A1/en
Publication of WO2003026555A2 publication Critical patent/WO2003026555A2/fr
Publication of WO2003026555A3 publication Critical patent/WO2003026555A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Cette invention se rapporte à un nouveau dispositif osmotique flottant qui est capable de distribuer un premier agent actif dans un enrobage extérieur, cette première administration étant immédiatement suivie par l'administration régulée continue d'un second agent actif à partir du noyau osmotique, pendant que la forme posologique flotte dans le fluide du milieu ambiant dans lequel elle est administrée. Ce dispositif osmotique flottant possède un noyau comprimé contenant un agent actif, une membrane semi-perméable entourant le noyau et perméable au fluide environnant et imperméable à l'agent actif, et un enrobage extérieur d'un ingrédient gazogène, un agent gélifiant, et un second agent actif. Des modes de réalisation particuliers de cette invention concernent des dispositifs osmotiques flottants dans lesquels les deux agents actifs sont semblables ou dissemblables.
PCT/IN2002/000124 2001-09-25 2002-05-28 Dispositif osmotique flottant pour l'administration de medicaments a liberation regulee WO2003026555A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002319893A AU2002319893A1 (en) 2001-09-25 2002-05-28 Floating osmotic device for controlled release drug delivery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN921/MUM/2001 2001-09-25
IN921MU2001 2001-09-25

Publications (2)

Publication Number Publication Date
WO2003026555A2 WO2003026555A2 (fr) 2003-04-03
WO2003026555A3 true WO2003026555A3 (fr) 2003-09-25

Family

ID=11097295

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2002/000124 WO2003026555A2 (fr) 2001-09-25 2002-05-28 Dispositif osmotique flottant pour l'administration de medicaments a liberation regulee

Country Status (3)

Country Link
AU (1) AU2002319893A1 (fr)
WO (1) WO2003026555A2 (fr)
ZA (1) ZA200204330B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269958B (zh) * 2018-03-17 2021-11-23 北京旭泽医药科技有限公司 一种含有卡波姆的助产凝胶组合物及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
US6004582A (en) * 1997-05-30 1999-12-21 Laboratorios Phoenix U.S.A, Inc. Multi-layered osmotic device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5558879A (en) * 1995-04-28 1996-09-24 Andrx Pharmaceuticals, Inc. Controlled release formulation for water soluble drugs in which a passageway is formed in situ
US6004582A (en) * 1997-05-30 1999-12-21 Laboratorios Phoenix U.S.A, Inc. Multi-layered osmotic device

Also Published As

Publication number Publication date
AU2002319893A1 (en) 2003-04-07
ZA200204330B (en) 2003-01-21
WO2003026555A2 (fr) 2003-04-03

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