WO2003016341A3 - Regulation of iron uptake - Google Patents

Regulation of iron uptake Download PDF

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Publication number
WO2003016341A3
WO2003016341A3 PCT/IB2002/003647 IB0203647W WO03016341A3 WO 2003016341 A3 WO2003016341 A3 WO 2003016341A3 IB 0203647 W IB0203647 W IB 0203647W WO 03016341 A3 WO03016341 A3 WO 03016341A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
iron uptake
dmt1
novel
characterization
Prior art date
Application number
PCT/IB2002/003647
Other languages
French (fr)
Other versions
WO2003016341A2 (en
Inventor
Nadia Hubert
Matthias Hentze
Original Assignee
European Molecular Biology Lab Embl
Nadia Hubert
Matthias Hentze
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by European Molecular Biology Lab Embl, Nadia Hubert, Matthias Hentze filed Critical European Molecular Biology Lab Embl
Priority to AU2002328117A priority Critical patent/AU2002328117A1/en
Publication of WO2003016341A2 publication Critical patent/WO2003016341A2/en
Publication of WO2003016341A3 publication Critical patent/WO2003016341A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to the isolation and characterization of a novel exon of the DMT1 (Divalent Metal Transporter 1) mRNA encoding a novel N-terminal domain of the DMT1 protein.
PCT/IB2002/003647 2001-08-17 2002-08-19 Regulation of iron uptake WO2003016341A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002328117A AU2002328117A1 (en) 2001-08-17 2002-08-19 Regulation of iron uptake

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0120148.2 2001-08-17
GBGB0120148.2A GB0120148D0 (en) 2001-08-17 2001-08-17 Regulation of iron uptake

Publications (2)

Publication Number Publication Date
WO2003016341A2 WO2003016341A2 (en) 2003-02-27
WO2003016341A3 true WO2003016341A3 (en) 2003-10-09

Family

ID=9920620

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/003647 WO2003016341A2 (en) 2001-08-17 2002-08-19 Regulation of iron uptake

Country Status (3)

Country Link
AU (1) AU2002328117A1 (en)
GB (1) GB0120148D0 (en)
WO (1) WO2003016341A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900008376A1 (en) * 2019-06-07 2020-12-07 Univ Degli Studi Di Modena E Reggio Emilia ANTIBODIES WITH ANTI-TUMOR ACTIVITY
CN115308422B (en) * 2022-09-28 2023-01-24 智泽童康(广州)生物科技有限公司 Use of iron-related factors in diagnosis of biliary atresia

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GUNSHIN HIROMI ET AL: "Cloning and characterization of a mammalian proton-coupled metal-ion transporter.", NATURE (LONDON), vol. 388, no. 6641, 1997, pages 482 - 488, XP002911580, ISSN: 0028-0836 *
HUBERT NADIA ET AL: "Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 99, no. 19, 17 September 2002 (2002-09-17), http://www.pnas.org September 17, 2002, pages 12345 - 12350, XP002244157, ISSN: 0027-8424 *
KISHI FUMIO ET AL: "Human natural resistance-associated macrophage protein 2: Gene cloning and protein identification.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 251, no. 3, 29 October 1998 (1998-10-29), pages 775 - 783, XP002244155, ISSN: 0006-291X *
LEE P L ET AL: "The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms.", BLOOD CELLS, MOLECULES & DISEASES, vol. 24, no. 9, 15 May 1998 (1998-05-15), pages 199 - 215, XP002244156, ISSN: 1079-9796 *

Also Published As

Publication number Publication date
AU2002328117A1 (en) 2003-03-03
GB0120148D0 (en) 2001-10-10
WO2003016341A2 (en) 2003-02-27

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