WO2003012103A3 - Nucleic acids coding for novel fbox proteins, their diagnostic and therapeutic uses - Google Patents

Nucleic acids coding for novel fbox proteins, their diagnostic and therapeutic uses Download PDF

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Publication number
WO2003012103A3
WO2003012103A3 PCT/FR2002/002783 FR0202783W WO03012103A3 WO 2003012103 A3 WO2003012103 A3 WO 2003012103A3 FR 0202783 W FR0202783 W FR 0202783W WO 03012103 A3 WO03012103 A3 WO 03012103A3
Authority
WO
WIPO (PCT)
Prior art keywords
novel
fbox
diagnostic
nucleic acids
therapeutic uses
Prior art date
Application number
PCT/FR2002/002783
Other languages
French (fr)
Other versions
WO2003012103A2 (en
Inventor
Dominique Thomas
Bruno Sargueil
Frederic Scaerou
Original Assignee
Cytomics Systems
Dominique Thomas
Bruno Sargueil
Frederic Scaerou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytomics Systems, Dominique Thomas, Bruno Sargueil, Frederic Scaerou filed Critical Cytomics Systems
Priority to AU2002337248A priority Critical patent/AU2002337248A1/en
Publication of WO2003012103A2 publication Critical patent/WO2003012103A2/en
Publication of WO2003012103A3 publication Critical patent/WO2003012103A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention concerns novel Fbox proteins and novel Fbox protein substrates. The invention provides screening methods for identifying the novel Fbox protein substrates and for identifying the small molecules and drugs which modulate the interaction and/or the activity of Fbox proteins and of their substrates.
PCT/FR2002/002783 2001-08-01 2002-08-01 Nucleic acids coding for novel fbox proteins, their diagnostic and therapeutic uses WO2003012103A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002337248A AU2002337248A1 (en) 2001-08-01 2002-08-01 Nucleic acids coding for novel fbox proteins, their diagnostic and therapeutic uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0110363A FR2828208A1 (en) 2001-08-01 2001-08-01 New nucleic acids encoding F-box proteins, useful e.g. for treatment of cancer or inflammation, also new proteins, antibodies and modulators
FR0110363 2001-08-01

Publications (2)

Publication Number Publication Date
WO2003012103A2 WO2003012103A2 (en) 2003-02-13
WO2003012103A3 true WO2003012103A3 (en) 2004-04-22

Family

ID=8866215

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2002/002783 WO2003012103A2 (en) 2001-08-01 2002-08-01 Nucleic acids coding for novel fbox proteins, their diagnostic and therapeutic uses

Country Status (3)

Country Link
AU (1) AU2002337248A1 (en)
FR (1) FR2828208A1 (en)
WO (1) WO2003012103A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088846A1 (en) * 1998-08-28 2006-04-27 Michele Pagano Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
AUPR278301A0 (en) 2001-01-31 2001-02-22 Bionomics Limited A novel gene
MX2012009318A (en) * 2010-02-10 2012-09-07 Novartis Ag Methods and compounds for muscle growth.
CN102382829B (en) * 2011-05-03 2013-06-26 中国人民解放军军事医学科学院放射与辐射医学研究所 FBXL15 protein inhibitor and application thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011995A1 (en) * 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
WO1999018989A1 (en) * 1997-10-16 1999-04-22 Baylor College Of Medicine F-box proteins and genes
WO2000012679A1 (en) * 1998-08-28 2000-03-09 New York University Novel ubiquitin ligases as therapeutic targets
WO2000075184A1 (en) * 1999-06-04 2000-12-14 Yale University Modulation of protein levels using the scf complex

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011995A1 (en) * 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
WO1999018989A1 (en) * 1997-10-16 1999-04-22 Baylor College Of Medicine F-box proteins and genes
WO2000012679A1 (en) * 1998-08-28 2000-03-09 New York University Novel ubiquitin ligases as therapeutic targets
WO2000075184A1 (en) * 1999-06-04 2000-12-14 Yale University Modulation of protein levels using the scf complex

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CENCIARELLI C ET AL: "IDENTIFICATION OF A FAMILY OF HUMAN F-BOX PROTEINS", CURRENT BIOLOGY, vol. 9, 1999, pages 1177 - 1179, XP000953487, ISSN: 0960-9822 *
CRAIG K L ET AL: "THE F-BOX: A NEW MOTIF FOR UBIQUITIN DEPENDENT PROTEOLYSIS IN CELL CYCLE REGULATION AND SIGNAL TRANSDUCTION", PROGRESS IN BIOPHYSICS AND MOLECULAR BIOLOGY, PERGAMON PRESS, OXFORD, GB, vol. 72, no. 3, 1999, pages 299 - 328, XP001024962, ISSN: 0079-6107 *
DATABASE EMBL [online] 29 September 2000 (2000-09-29), XP002201883, Database accession no. AK026541 *

Also Published As

Publication number Publication date
WO2003012103A2 (en) 2003-02-13
FR2828208A1 (en) 2003-02-07
AU2002337248A1 (en) 2003-02-17

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