WO2003007842A2 - Stents - Google Patents

Stents Download PDF

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Publication number
WO2003007842A2
WO2003007842A2 PCT/ZA2002/000116 ZA0200116W WO03007842A2 WO 2003007842 A2 WO2003007842 A2 WO 2003007842A2 ZA 0200116 W ZA0200116 W ZA 0200116W WO 03007842 A2 WO03007842 A2 WO 03007842A2
Authority
WO
WIPO (PCT)
Prior art keywords
ring
bars
adjacent
longitudinals
stent
Prior art date
Application number
PCT/ZA2002/000116
Other languages
French (fr)
Other versions
WO2003007842A3 (en
Inventor
Gregory Richard Starke
Markus Lehmann
Damian John Conway
Original Assignee
Disa Vascular (Pty) Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ZA2001/3691 priority Critical
Priority to ZA200103691 priority
Application filed by Disa Vascular (Pty) Ltd filed Critical Disa Vascular (Pty) Ltd
Publication of WO2003007842A2 publication Critical patent/WO2003007842A2/en
Publication of WO2003007842A3 publication Critical patent/WO2003007842A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541Adjacent bands are arranged out of phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155Adjacent bands being connected to each other
    • A61F2002/91558Adjacent bands being connected to each other connected peak to peak
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028Shapes in the form of latin or greek characters
    • A61F2230/0054V-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir

Abstract

A stent (22) of cylindrical form is disclosed which comprises a plurality of rings (24) extending around the stent's longitudinal axis. The rings (24) are spaced apart along the axis and are joined to one another by longitudinals (26) each of which spans between one ring and an adjacent ring. Each ring (24) is of zig-zag form and comprises bars (28) all of which are parallel to one another and bars (30) all of which are parallel to one another and at an angle to the bars (28). The bars (28, 30) alternate and are joined to one another by way of hairpin bends (32). the longitudinals (26) join the hairpin bends (32) of one ring to the hairpin bends (32) of the adjacent ring. Each of the rings has, between each adjacent pair of longitudinals (considered in the circumferential direction) at least two, or any multiple of two, hairpin bends (32) which are not joined to hairpin bends (32) of the adjacent ring.

Description

STENTS

FIELD OF THE INVENTION

THIS INVENTION relates to stents.

BACKGROUND TO THE INVENTION

A stent is used medically in any one of a multiplicity of vessels of the

human body to maintain its patency.

Applicant is aware of European patent specifications EP 0 669 114 B1 ,

EP 0 821 920 B1 and EP 0 821 921 A1 and US specifications 5733303, 5195984,

5102417, 4733665, 6179867, 5514154, 6068656, 6190403, 5913895 and 5643312

which disclose stents of various types.

The object of the present invention is to provide a stent with improved

radial expansion capabilities and minimal longitudinal contraction during radial

expansion.

BRIEF DESCRIPTION OF THE INVENTION

According to one aspect of the present invention there is provided a stent

of cylindrical form which comprises a plurality of rings extending around the stent's longitudinal axis, the rings being spaced apart along the axis and being joined to one

another by longitudinals each of which spans between one ring and an adjacent ring,

characterized in that each ring is of zig-zag form and comprises a plurality of first bars

all of which are parallel to one another and a plurality of second bars all of which are

parallel to one another and at an angle to the bars of the first set of bars, first bars

alternating with second bars and each first bar being joined at each end thereof to the

adjacent second bars by way of hairpin bends, the longitudinals joining the hairpin

bends of one ring to the hairpin bends of the adjacent ring, each of these rings having

between each adjacent pair of longitudinals, considered in the circumferential direction,

at least two, or any multiple of two, hairpin bends which are not joined to hairpin bends

of the adjacent ring.

Each bar preferably has end portions contiguous with the hairpin bends

that join it to adjacent bars and a centre portion which joins said end portions to one

another, the centre portion being of non-linear configuration.

Each ring can be a mirror image of the ring, or rings, adjacent thereto

about radial planes passing through the midpoints of the longitudinals.

In a specific form said one ring and said adjacent ring each comprise

three first bars, three second bars and five hairpin bends between each of said adjacent

pairs of longitudinals thereby providing the two non-joined hairpin bends on the facing sides of said rings and three hairpin bends on the sides of the rings which face away

from another, the centre ones of these hairpin bends being joined by longitudinals to

further rings.

According to another aspect of the present invention there is provided a

stent of cylindrical form which comprises a plurality of rings extending around the stent's

longitudinal axis, the rings being spaced apart along the axis and being joined to one

another by longitudinals each of which spans between one ring and an adjacent ring,

each ring being of zig-zag form and comprising a plurality of first bars all of which are

parallel to one another and a plurality of second bars all of which are parallel to one

another and at an angle to the bars of the first set of bars, first bars alternating with

second bars and each first bar being joined at each end thereof to the adjacent second

bars by way of hairpin bends, the longitudinals joining the hairpin bends of one ring to

the hairpin bends of the adjacent ring, each of these rings having between each

adjacent pair of longitudinals, considered in the circumferential direction, at least two, or

any multiple of two, hairpin bends which are not joined to hairpin bends of the adjacent

ring, each longitudinal connecting a first ring to a second ring being midway between,

considered in the circumferential direction, two further longitudinals which connect the

first ring to a further ring and midway between two additional longitudinals which

connect the second ring to another ring, the further longitudinals being spaced the

same circumferential distance from one another as the two additional longitudinals are

spaced from one another and which is the same distance as the spacing between the longitudinals connecting the first and second rings.

According to a further aspect of the present invention there is provided a

stent of cylindrical form which comprises a plurality of rings extending around the stent's

longitudinal axis, the rings being spaced apart along the axis and being joined to one

another by longitudinals each of which spans between one ring and an adjacent ring,

each ring being of zig-zag form and comprising a plurality of first bars all of which are

parallel to one another and a plurality of second bars all of which are parallel to one

another and at an angle to the bars of the first set of bars, first bars alternating with

second bars and each first bar being joined at each end thereof to the adjacent second

bars by way of hairpin bends, the longitudinals joining the bends of one ring to the

bends of the adjacent ring, each longitudinal being of sinusoidal or generally sinusoidal

form, there being a first junction where one end of the longitudinal is joined to one ring

and a second junction where the other end of the longitudinal is joined to an adjacent

ring, said first junction being displaced circumferentially around the stent with respect to

the second junction, each ring being a mirror image of the adjacent ring whereby each

hairpin bend of said one ring is axially aligned with one of the hairpin bends of said

adjacent ring.

Each group of three rings can comprise a centre ring, a first adjacent ring

on one side of the centre ring and a second adjacent ring on the other side of the

centre ring, alternate hairpin bends on one side of the centre ring being joined by longitudinals to the first adjacent ring and alternate hairpin bends on the other side of

the centre ring being joined by longitudinals to the second adjacent ring.

In a configuration which reduces stress concentrations at the hair pin

bends, each bar of the stent can be narrower considered in the circumferential

direction, than the width of the hairpin bends considered in the axial direction.

To improve radio opacity each bar of the stent can have a centre section

and end sections on each side of the centre section, the end sections being narrower,

considered in the circumferential direction, than the centre section.

BRIEF DESCRIPTION OF THE DRAWINGS

For a better understanding of the present invention, and to show how the

same may be carried into effect, reference will now be made, by way of example, to the

accompanying drawings in which:-

Figure 1 illustrates a stent in layflat form;

Figure 2 illustrates another stent in layflat form;

Figure 3 illustrates a detail of a stent;

Figure 4 illustrates a further stent detail;

Figure 5 illustrates a number of bars and hairpin bends of a stent; and

Figure 6 illustrates a further form of stent. DETAILED DESCRIPTION OF THE DRAWINGS

Referring firstly to Figure 1 the stent 10 illustrated is of cylindrical form and

comprises a plurality of rings 12 which extend around the stent's longitudinal axis. For

ease of illustration the stent has been shown in the form it adopts if split longitudinally

and flattened.

The rings 12 are spaced apart along the longitudinal axis of the stent and

are joined to one another by longitudinals 14 which span between one ring 12 and an

adjacent ring 12.

Each ring 12 is of zig-zag form and comprises a plurality of first bars 16 all

of which are parallel to one another and a plurality of second bars 18 all of which are

parallel to one another and at an angle to the bars 16. Bars 16 alternate with bars 18.

The bars are joined to one another by way of hairpin bends 20.

Each longitudinal 14 joins a hairpin bend 20 of one ring 12 to a hairpin

bend 20 of the adjacent ring. This arrangement enables longitudinals of sufficient

length to be obtained without having to increase the spacing between adjacent rings.

As will be seen from Figure 1 , not all the hairpin bends are joined to one

another. More specifically, between each pair of longitudinals and the hairpin bends joined by them, considered in the circumferential direction, each ring 12 has two hairpin

bends 20 which are not joined to the hairpin bends of adjacent rings. To distinguish

between them, the hairpin bends of one pair of joined hairpin bends have been

designated 20.1 and a non-joined pair 20.2.

Each longitudinal is of S-configuration, one end of each longitudinal being

spaced from the other end both in the axial direction of the stent and also in the

circumferential direction of the stent. This arrangement enables longitudinals of

sufficient length to be obtained without having to increase the spacing between

adjacent rings.

Each bar 16, 18 is non-linear in configuration. More specifically each bar

16 has end portions 16.1 , 16.2 which are approximately straight and in alignment with

one another and a centre portion 18.3 which is of non-linear curved configuration and

joins the end portions 16.1 , 16.2 to one another.

A consideration of Figure 1 reveals that each ring 12 is a mirror image of

the adjacent ring. To illustrate this the rings 12.1 and 12.2 are mirror images of one

another about the line AA.

Turning now to Figure 2, the illustrated stent 22 is again shown in

longitudinally split flat form. The stent comprises a plurality of rings 24 which extend around the stent's longitudinal axis and are spaced apart along the axis. The rings 24

are joined to one another by longitudinals 26 which span between one ring 24 and an

adjacent ring 24.

Each ring 24 is of zig-zag form and comprises a plurality of bars 28 all of

which are parallel to one another and a plurality of bars 30 which are also parallel to

one another. The bars 28 are at an angle to the bars 30, bars 30 alternating with bars

28 and each bar 30 being joined at each thereof to two adjacent bars 28 by way of

hairpin bends 32.

The longitudinals 26 join the bends 32 of one ring 24 to the bends 32 of

the adjacent ring. Each longitudinal 26 is of sinusoidal form. There is a junction at 34

where one end of the longitudinal 26 is joined to one hairpin bend 32 and another

junction at 36 where the other end of the longitudinal is joined to an adjacent ring. Each

first junction 34 at one end of a longitudinal 26 is displaced circumferentially around the

stent with respect to the second junction 36 between that longitudinal and the adjacent

ring. This again permits longitudinals 26 to be obtained which are of a length sufficient

to counter stent shortening on radial expansion.

The configuration of the stent is such that the rings can be considered to

be in groups of three. Three rings forming a group are designated 24.1 , 24.2 and 24.3

in Figure 2. The centre ring 24.2 of the group is joined to the rings on both sides thereof. More specifically, alternate hairpin bends, designated 32.1, on one side of the

centre ring 24.2 are joined by longitudinals designated 26.1 to the ring 24.1 on one side

thereof and alternate hairpin bends 32.2 on the other side of the centre ring 24.2 are

joined by longitudinals designated 26.2 to the ring 24.3.

When the cylindrical stent is expanded, the hairpin bends 20 open out to

enable the diameter of the stent to be increased. Inevitably the opening out of the

bends tends simultaneously to narrow each ring in the axial direction. Straightening of

the longitudinals accommodates this narrowing of the rings without foreshortening the

stent.

To minimise the strains imposed on the stent during expansion, it can

have the configuration shown in Figure 3. In this form the width W1 of the hairpin

bends is greater than the width W2 of the bars. This concentrates the greatest areas of

stress away from the hairpin bends and reduces the prospects of stress at the bends

fracturing the bends.

The stents described above are of an eight cell design. A stent of six cell

design has less metal content than a stent of eight cell design. In order to improve the

radio opacity of a six cell stent, it preferably has the configuration shown in Figure 4. In

this form the width W3 of the centre section of each bar is greater than the width W4 of

each end section of each bar and also greater than the width of the hairpin bend. The stent shown in Figure 5 comprises bars 38 and hairpin bends 40. To

provide for local delivery of drugs to the site of implantation, the bars have slots 42 cut

through them or grooves or recesses 44 cut into them. Where grooves or recesses are

provide, these can be on the radially inner faces of the bars, or the radially outer faces

or both. Areas of high plastic deformation must be avoided when choosing the

positions for the slot and/or grooves. The slots and/or grooves provide reservoirs in

which slow release drugs can be located within a polymer substrate or other binder.

More or larger slots can be provided where there is a greater need for drug elution.

The ends of the stent are places where higher drug concentrations can be required.

The drugs are released into the tissue or bloodstream over a period of time.

The stent shown in Figure 6 has rings designated 46, 48 and 50. The

bars are designated 52, 54 and the hairpin bends 56.

The bars 52, 54 of the ring 46 are longer than the bars of the ring 48

which in turn are longer than the bars of the ring 50. If the bars of the rings towards the

ends of the stent are shorter than the bars of the rings towards the middle of the stent,

this provides for greater stiffness towards the ends of the stent. This resists flaring o

the ends of the stent as it is expanded. It will be understood that any arrangement of

bar lengths can be chosen to provide ring-like zones of greater strength and ring-like

zones of lesser strength in any desired pattern. It is also possible to provide rings with different stiffnesses by varying the

widths of the hairpin bends, considered in the axial direction. Thus hairpin bends of

greater axial width can be provided at the ends of the stent to resist flaring of the ends

during expansion. The widths of the hairpin bends in the axial direction will always be

greater than the widths of the bars in the circumferential direction. Thus in Figure 3

W2/W1 will always be greater than 1.

The bars can include through slots and/or recesses for receiving drugs

which are to be released into the recipient of the stent.

To provide rings of differing stiffness the widths of the hairpin bends,

measured in the axial direction, can vary from one ring to another. A similar variation in

stiffness can be provided by means of bars which in one ring are of a different length to

the bars in another ring.

Claims

CLAIMS:
1. A stent of cylindrical form which comprises a plurality of rings extending
around the stent's longitudinal axis, the rings being spaced apart along the axis and
being joined to one another by longitudinals each of which spans between one ring and
an adjacent ring, each ring being of zig-zag form and comprising a plurality of first bars
all of which are parallel to one another and a plurality of second bars all of which are
parallel to one another and at an angle to the bars of the first set of bars, first bars
alternating with second bars and each first bar being joined at each end thereof to the
adjacent second bars by way of hairpin bends, the longitudinals joining the hairpin
bends of one ring to the hairpin bends of the adjacent ring, each of these rings having
between each adjacent pair of longitudinals, considered in the circumferential direction,
at least two, or any multiple of two, hairpin bends which are not joined to hairpin bends
of the adjacent ring.
2. A stent as claimed in claim 1 , wherein each bar has end portions
contiguous with the hairpin bends that join it to adjacent bars and a centre portion which
joins said end portions to one another, the centre portion being of non-linear
configuration.
3. A stent as claimed in claim 1 or 2, wherein each ring is a mirror image of
the ring, or rings, adjacent thereto about radial planes passing through the midpoints of the longitudinals.
4. A stent as claimed in claim 1 or 2, wherein said one ring and said adjacent
ring each comprise three first bars, three second bars and five hairpin bends between
each of said adjacent pairs of longitudinals thereby providing the two non-joined hairpin
bends on the facing sides of said rings and three hairpin bends on the sides of the rings
which face away from another, the centre ones of these hairpin bends being joined by
longitudinals to further rings.
5. A stent of cylindrical form which comprises a plurality of rings extending
around the stent's longitudinal axis, the rings being spaced apart along the axis and
being joined to one another by longitudinals each of which spans between one ring and
an adjacent ring, each ring being of zig-zag form and comprising a plurality of first bars
all of which are parallel to one another and a plurality of second bars all of which are
parallel to one another and at an angle to the bars of the first set of bars, first bars
alternating with second bars and each first bar being joined at each end thereof to the
adjacent second bars by way of hairpin bends, the longitudinals joining the hairpin
bends of one ring to the hairpin bends of the adjacent ring, each of these rings having
between each adjacent pair of longitudinals, considered in the circumferential direction,
at least two, or any multiple of two, hairpin bends which are not joined to hairpin bends
of the adjacent ring, each longitudinal connecting a first ring to a second ring being
midway between, considered in the circumferential direction, two further longitudinals which connect the first ring to a further ring and midway between two additional
longitudinals which connect the second ring to another ring, the further longitudinals
being spaced the same circumferential distance from one another as the two additional
longitudinals are spaced from one another and which is the same distance as the
spacing between the longitudinals connecting the first and second rings.
6. A stent of cylindrical form which comprises a plurality of rings extending
around the stent's longitudinal axis, the rings being spaced apart along the axis and
being joined to one another by longitudinals each of which spans between one ring and
an adjacent ring, each ring being of zig-zag form and comprises a plurality of first bars
all of which are parallel to one another and a plurality of second bars all of which are
parallel to one another and at an angle to the bars of the first set of bars, first bars
alternating with second bars and each first bar being joined at each end thereof to the
adjacent second bars by way of hairpin bends, the longitudinals joining the bends of
one ring to the bends of the adjacent ring, each longitudinal being of sinusoidal or
generally sinusoidal form, there being a first junction where one end of the longitudinal
is joined to one ring and a second junction where the other end of the longitudinal is
joined to an adjacent ring, said first junction being displaced circumferentially around
the stent with respect to the second junction, each ring being a mirror image of the
adjacent ring whereby each hairpin bend of said one ring is axially aligned with one of
the hairpin bends of said adjacent ring.
7. A stent as claimed in claim 6, wherein each longitudinal is joined to said
one ring at the junction between a first bar of said one ring and the hairpin bend at the
end of said first bar and is joined to the adjacent ring at the junction between a first bar
of said adjacent ring and the hairpin bend at the end of said first bar of the adjacent
ring, said first bars being in alignment with one another.
8. A stent as claimed in claim 6 or 7, wherein each group of three rings
comprises a centre ring, a first adjacent ring on one side of the centre ring and a
second adjacent ring on the other side of the centre ring, alternate hairpin bends on one
side of the centre ring being joined by longitudinals to the first adjacent ring and
alternate hairpin bends on the other side of the centre ring being joined by longitudinals
to the second adjacent ring.
9. A stent as claimed in any one of claims 1 to 8, wherein each bar of the
stent is narrower, considered in the circumferential direction, than the width of the
hairpin bends considered in the axial direction.
10. A stent as claimed in any one of claims 1 to 9, wherein each bar
comprises a centre section and end sections on each side of the centre section, the
end sections being narrower, considered in the circumferential direction, than the centre
section.
PCT/ZA2002/000116 2001-07-18 2002-07-18 Stents WO2003007842A2 (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005120397A1 (en) 2004-06-07 2005-12-22 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
WO2007102855A1 (en) * 2006-03-07 2007-09-13 Boston Scientific Scimed, Inc. Bifurcated stent with improved securement
US7896912B2 (en) 1998-03-30 2011-03-01 Innovational Holdings, Llc Expandable medical device with S-shaped bridging elements
US7909865B2 (en) 1998-03-30 2011-03-22 Conor Medsystems, LLC Expandable medical device for delivery of beneficial agent
US8202313B2 (en) 2000-10-16 2012-06-19 Innovational Holdings Llc Expandable medical device with beneficial agent in openings
US8206435B2 (en) 1998-03-30 2012-06-26 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US8361537B2 (en) 1998-03-30 2013-01-29 Innovational Holdings, Llc Expandable medical device with beneficial agent concentration gradient
US8915954B2 (en) 2003-05-06 2014-12-23 Abbott Laboratories Endoprosthesis having foot extensions

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216267B2 (en) 2006-09-12 2012-07-10 Boston Scientific Scimed, Inc. Multilayer balloon for bifurcated stent delivery and methods of making and using the same
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4733665A (en) 1985-11-07 1988-03-29 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US5195984A (en) 1988-10-04 1993-03-23 Expandable Grafts Partnership Expandable intraluminal graft
EP0821921A1 (en) 1996-06-11 1998-02-04 David R. Fischell Multi-cell stent with cells having differing characteristics
US5733303A (en) 1994-03-17 1998-03-31 Medinol Ltd. Flexible expandable stent
EP0669114B1 (en) 1994-02-25 1998-06-03 David R. Fischell Stent having a multiplicity of closed circular structures
US6179867B1 (en) 1998-01-16 2001-01-30 Advanced Cardiovascular Systems, Inc. Flexible stent and method of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2764794B1 (en) * 1997-06-20 1999-11-12 Nycomed Lab Sa A tubular expands a variable thickness
WO2000071053A1 (en) * 1999-05-19 2000-11-30 Eurocor Gmbh Radially expandable vessel support
DE19952295A1 (en) * 1999-10-29 2001-05-23 Angiomed Ag A method of making a stent

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4733665A (en) 1985-11-07 1988-03-29 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US5102417A (en) 1985-11-07 1992-04-07 Expandable Grafts Partnership Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft
US4733665B1 (en) 1985-11-07 1994-01-11 Expandable Grafts Partnership Expandable intraluminal graft,and method and apparatus for implanting an expandable intraluminal graft
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US5195984A (en) 1988-10-04 1993-03-23 Expandable Grafts Partnership Expandable intraluminal graft
EP0669114B1 (en) 1994-02-25 1998-06-03 David R. Fischell Stent having a multiplicity of closed circular structures
EP0821920B1 (en) 1994-02-25 2000-01-19 David R. Fischell Stent
US5733303A (en) 1994-03-17 1998-03-31 Medinol Ltd. Flexible expandable stent
EP0821921A1 (en) 1996-06-11 1998-02-04 David R. Fischell Multi-cell stent with cells having differing characteristics
US6179867B1 (en) 1998-01-16 2001-01-30 Advanced Cardiovascular Systems, Inc. Flexible stent and method of use

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8052735B2 (en) 1998-03-30 2011-11-08 Innovational Holdings, Llc Expandable medical device with ductile hinges
US8361537B2 (en) 1998-03-30 2013-01-29 Innovational Holdings, Llc Expandable medical device with beneficial agent concentration gradient
US8439968B2 (en) 1998-03-30 2013-05-14 Innovational Holdings, Llc Expandable medical device for delivery of beneficial agent
US8206435B2 (en) 1998-03-30 2012-06-26 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US7896912B2 (en) 1998-03-30 2011-03-01 Innovational Holdings, Llc Expandable medical device with S-shaped bridging elements
US7909865B2 (en) 1998-03-30 2011-03-22 Conor Medsystems, LLC Expandable medical device for delivery of beneficial agent
US8052734B2 (en) 1998-03-30 2011-11-08 Innovational Holdings, Llc Expandable medical device with beneficial agent delivery mechanism
US8202313B2 (en) 2000-10-16 2012-06-19 Innovational Holdings Llc Expandable medical device with beneficial agent in openings
US8915954B2 (en) 2003-05-06 2014-12-23 Abbott Laboratories Endoprosthesis having foot extensions
AU2005251777B2 (en) * 2004-06-07 2011-10-27 Innovational Holdings, Llc Expandable medical device for delivery of beneficial agent
EP2335647A1 (en) * 2004-06-07 2011-06-22 Innovational Holdings, LLC Expandable medical device for the delivery of a beneficial agent
EP1768609A4 (en) * 2004-06-07 2009-04-08 Conor Medsystems Inc Expandable medical device for delivery of beneficial agent
JP2008508989A (en) * 2004-06-07 2008-03-27 コナー メドシステムズ, インコーポレイテッドConor Medsystems, Inc. The expandable medical device for delivery of beneficial agent
EP1768609A1 (en) * 2004-06-07 2007-04-04 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
WO2005120397A1 (en) 2004-06-07 2005-12-22 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
WO2007102855A1 (en) * 2006-03-07 2007-09-13 Boston Scientific Scimed, Inc. Bifurcated stent with improved securement

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