WO2003002982A1

WO2003002982A1 - Light stability testing device

Info

Publication number: WO2003002982A1
Application number: PCT/JP2002/004840
Authority: WO
Inventors: Hiroshi Tsukuda
Original assignee: Nagano Science Equipment Mfg. Co., Ltd.
Priority date: 2001-06-29
Filing date: 2002-05-20
Publication date: 2003-01-09
Also published as: JPWO2003002982A1

Abstract

A light stability testing device comprising a light source, an optical system for regulating light emitted from the light source, a sample table for mounting thereon a sample to be irradiated with light passing through the optical system, and an optical sensor attached to the sample table, for measuring the dose of light, wherein the optical sensor has a visible light measuring sensor (5) for measuring the dose of visible light, a ultraviolet measuring sensor (6) for measuring the dose of ultraviolet ray, and an intermediate wavelength light measuring sensor (7) for measuring the dose of an intermediate wavelength light between visible light and ultraviolet ray, whereby the light stability testing device can conduct an accurate light stability test even on a medicine having a large degree of deterioration in an intermediate wavelength area (400 nm-500 nm).

Description

Description Light stability test equipment Technical field

The present invention relates to a light stability test apparatus for testing the light stability of, for example, chemicals. Background art

A conventional light stability test apparatus will be described with reference to FIGS. 4, 5, 6, 7, and 8. FIG.

FIG. 4 is a main part front view showing a light stability test apparatus according to a conventional technique. This light stability test device 1 is a device for adjusting the light emitted from a light source 2 by an optical system 3 and irradiating the light on a sample (not shown) mounted on a sample stage 4 to test the light stability of the sample. is there. The optical system 3 mainly includes a first reflecting mirror 31, a beam adjusting means 33, an integrated lens 35 as a light flux controlling means, a second reflecting mirror 37, and a third reflecting mirror 39. . The integrated lens 35 is made up of a bunch of chi-yoke-shaped quartz rods, and a spherical glass is attached to the upper part. When a light beam passes here, each quartz column behaves like a small light source. Thereby, for example, even if the light beam passing through the predetermined aperture is rectangular, it can be changed to a circular light beam.

Reference numeral 4 denotes a sample stage for mounting a sample (not shown), a visible light measuring sensor 5 for measuring the amount of visible light irradiated on the sample stage 4, and an ultraviolet measuring sensor for measuring the amount of ultraviolet irradiation. 6 is installed. The sample stage 4 is rotatable via a rotating shaft 71 by a driving force of a driving device 7. In the light stability test apparatus 1 according to the prior art, the light stability test apparatus 1 is largely divided into a lamp house 8 and a sample chamber 9. Means 33, an integrated lens 35 as a light flux controlling means and a second reflecting mirror 37 are installed in a lamp house 8, and a third reflecting mirror 39 and a sample stage 4 of the optical system 3 are provided. It is installed in the sample room 9.

The light beam adjusting means 33 in the optical system 3 has a stop which is a total light beam adjusting means and an ultraviolet ray limiting filter which is an ultraviolet ray adjusting means. The stop, which is a means for controlling all rays, controls and adjusts the amount of all visible light and ultraviolet rays uniformly, and the filter for limiting ultraviolet light, which is means for controlling ultraviolet rays, only filters out ultraviolet rays (particularly, far ultraviolet rays). To control. The light source

As for 2, a xenon lamp is used.

In the light stability test apparatus 1 having the above configuration, first, a sample (not shown) is placed on the sample stage 4. Then, a light beam is emitted from the xenon lamp of the light source 2. This light beam is first condensed by the first reflecting mirror 31, and then passes through an ultraviolet ray limiting filter, which is an ultraviolet ray adjusting means for limiting ultraviolet rays in the light ray adjusting means 33. Thereafter, the light is passed through a stop, which is a total light adjusting means, in order to adjust and limit the total amount of light, that is, the amount of all visible light and ultraviolet light. After that, the direction of the light beam is adjusted by the integrated lens 35 as a light flux controlling means. Thereafter, the direction of the light beam is changed to a substantially horizontal direction by the second reflecting mirror 37 and enters the sample chamber 9, and is further reflected downward by the third reflecting mirror 39 to irradiate a sample (not shown) mounted on the sample stage 4. . Since the irradiation is performed for a long time, the sample stage 4 is rotated by the driving device 7 via the rotating shaft 71 during irradiation to improve the irradiation distribution, and the light stability of the sample is tested. Will be.

During the irradiation, the sensor for visible light measurement 5 or the sensor for ultraviolet light measurement A signal from any one of the sixteen is transmitted to a control unit (not shown), and the control unit calculates and controls the light amount and time.

During irradiation, the light amount of the light source 2 is adjusted by a signal from the visible light measurement sensor 5. Further, the measured values by the ultraviolet ray measuring sensor 6 are integrated and recorded.

However, the light stability test apparatus 1 according to the above prior art has the following problems.

FIG. 7 is a diagram showing the spectral distribution of sunlight, a xenon lamp, and a D65 lamp (FLR20S-D-EDL-D65 / M, manufactured by Toshiba). The horizontal axis shows the wavelength, and the vertical axis shows the relative value of the intensity. As shown in FIG. 8, the spectral distribution of the xenon lamp and the D65 lamp, which is a light source approximated by sunlight, has an excess ultraviolet ray portion as compared with the spectral distribution of sunlight.

On the other hand, the standards of the Ministry of Health and Welfare in the photostability test of pharmaceuticals, etc. as samples are based on sunlight.Specifically, the integrated irradiation dose is more than 1200 kLxhr for visible light and It is specified as 200 whr / m ² or more.

Therefore, in the light stability test apparatus 1, only the two light sensors described above, that is, the visible light measurement sensor 5 and the ultraviolet light measurement sensor 6, are attached to the sample stage 6. FIG. 5 shows the sensitivity distribution of the visible light measuring sensor 5 and the ultraviolet light measuring sensor 6. In FIG. 5, b is the sensitivity of the visible light measuring sensor 5, that is, the sensitivity of the illuminometer to visible light, which is close to the so-called relative luminous efficiency. On the other hand, a is the sensitivity of the ultraviolet ray measuring sensor 16 and approximates the light source distribution of black light. The measurement definition of ultraviolet light is defined as "350 nm to 370 nm", and the FDA clearly defines it as "black light spectrum distribution". As is clear from FIG. 5, there is almost no sensitivity near the wavelength of 400 nm to 500 nm. When the distribution of the light source spectrum is assumed to be constant, such as sunlight, the overall intensity is represented by the above two sensors, namely, the visible light measurement sensor 5 and the ultraviolet measurement sensor 6. Enough to do.

However, if the light source changes and various patterns of spectral distribution are expected, there may be a difference in the light irradiation effect, that is, the test result. For example, as shown in FIG. 6, one drug, menatrene (vitamin B 1) has a large degree of deterioration in the intermediate wavelength region. Fig. 6 is a graph showing the degree of degradation of menatrene (vitamin B1) for each spectrum. When the integrated irradiation amount of sunlight, xenon light source and D65 light source is applied to the drug menatrene (vitamin B1) having this deterioration curve by 1,200 kLX hr, respectively, the degree of deterioration is as follows. It became like. The irradiation amount of the ultraviolet rays was set to 220 whr / m ² by controlling an ultraviolet filter which is an ultraviolet adjusting means. FIG. 8 is a diagram showing the transmittance of the ultraviolet filter at this time. The degree of deterioration is a relative evaluation with sunlight as 1.

Light source Visible light cumulative irradiation Ultraviolet light cumulative irradiation Deterioration Degree of light 1 200 kL xhr 22 0 whr / m ² 1.000 Xenon light source 1 200 kL xhr 22 0 whr / m 1 2 1 D 6 5 Light source 1 200 kL xhr 220 whr / m 1.16 As shown in the above test results, this drug menatrene (vitamin B 1) has the same irradiation in the conventional evaluation. Even if irradiation is performed in such a way, the degree of deterioration will differ depending on the light source used. In addition, many other common drugs have similar properties.

As described above, for a medicine having a large degree of deterioration in the intermediate wavelength region (400 nm to 500 nm), the degree of deterioration differs depending on the light source used. There is a problem that an accurate light stability test is difficult.

Therefore, the present invention has been made to solve the above-mentioned problems, and it has been found that accurate photostability can be achieved even for a drug having a large degree of deterioration in the intermediate wavelength region (400 nm to 500 nm). An object of the present invention is to provide a light stability test device capable of performing a test. Disclosure of the invention

In order to achieve the above object, a light stability test apparatus according to the present invention includes a light source, an optical system for adjusting a light beam emitted from the light source, and a sample to be irradiated with the light beam passing through the optical system. A light stability test apparatus having a sample stage and an optical sensor attached to the sample stage for measuring an irradiation amount of a light beam, wherein the optical sensor is for measuring a visible light irradiation amount for measuring a visible light irradiation amount. It has a sensor, an ultraviolet ray measuring sensor for measuring the irradiation amount of ultraviolet light, and an intermediate wavelength light measuring sensor for measuring the irradiation amount of intermediate wavelength light between the visible light and the ultraviolet light. Here, “visible light” refers to light having a wavelength of mainly 500 nm to 780 nm, and “ultraviolet light” mainly refers to light having a wavelength of 200 nm to 400 nm. In other words, “intermediate wavelength light” refers to light having a wavelength of mainly from 400 11111 to 500 nm.

Also, a light stability having a light source, a sample stage on which a sample to be irradiated with the light beam emitted from the light source is mounted, and an optical sensor attached to the sample stage for measuring the irradiation amount of the light beam. In the test apparatus, the optical sensor is a visible light measurement sensor that measures the amount of visible light irradiation, an ultraviolet light measurement sensor that measures the amount of ultraviolet light irradiation, and an irradiation amount of an intermediate wavelength light between visible light and ultraviolet light. It has an intermediate-wavelength light measurement sensor to be measured. It also has a measurement value table that displays the measurement values of the intermediate-wavelength light measurement sensor It is preferable to have an indicator.

Further, it is preferable that the measured value display section has an integrated value display section for displaying an integrated value obtained by integrating the measured values at each time point.

Further, it is preferable that the measurement value display section has an instantaneous value display section for displaying an instantaneous value which is a measurement value at each time point.

Further, it is preferable that a control unit that controls the optical system by transmitting a signal from the intermediate wavelength light beam measurement sensor is provided.

In addition, it is preferable to have a control unit that controls the light source by transmitting a signal from the intermediate wavelength light measurement sensor. “Controlling the light source” means, for example, increasing or decreasing the amount of light emitted from the light source, or increasing or decreasing the irradiation time.

Further, the sensitivity peak value of the intermediate wavelength light measuring sensor is preferably in the range of 400 nm to 500 nm.

Further, the sensitivity peak value of the intermediate wavelength light measuring sensor is preferably in the range of 450 nm to 450 nm.

Further, the sensitivity peak value of the ultraviolet light measuring sensor is preferably in a range from 350 nm to 370 nm.

In addition, the sensitivity peak value of the visible light measurement sensor is preferably in the range of 550 nm to 560 nm.

In addition, the light source, an optical system for adjusting the light beam emitted from the light source, a sample stage on which a sample to be irradiated with the light beam passing through the optical system is mounted, and the irradiation amount of the light beam attached to the sample stage is determined. In a light stability test apparatus having an optical sensor for measurement, the optical sensor is a spectroradiometer, and the spectrum is evaluated from 400 nm to 500 nm for an intermediate wavelength light beam. A spectrum distribution having a peak value of nm may be used as the weighted evaluation coefficient. Also, a light stability having a light source, a sample stage on which a sample to be irradiated with the light beam emitted from the light source is mounted, and an optical sensor attached to the sample stage for measuring the irradiation amount of the light beam. In the test apparatus, the optical sensor is a spectroradiometer, and the spectrum is evaluated by a spectrum having a peak value of 400 nm to 500 nm for an intermediate wavelength light beam. The distribution may be used as the weighted evaluation coefficient.

Further, the optical sensor is a spectroradiometer, and the spectrum is evaluated by weighting a spectrum distribution having a peak value of 450 nm to 470 nm for an intermediate wavelength light beam. It is preferable to use an evaluation coefficient.

The optical sensor is a spectroradiometer, and the spectrum is evaluated by weighting a spectrum distribution having a peak value of 35 O nm to 37 O nm for ultraviolet rays. It is preferable to use an evaluation coefficient.

Further, the optical sensor is a spectroradiometer, and the spectrum is evaluated by weighting the spectrum distribution having a peak value of 55 O nm to 56 O nm for visible light. Preferably, it is a coefficient.

Further, it is preferable to have a measurement value display unit for displaying a measurement value of the irradiation amount of the intermediate wavelength light beam by the spectroradiometer.

Further, it is preferable to have a control unit for controlling the optical system by transmitting a signal of the measured value of the irradiation amount of the intermediate wavelength light beam by the spectroradiometer.

In addition, it is preferable to have a control unit that controls the light source by transmitting a signal from the intermediate wavelength light measurement sensor. Preferably, the sample stage is rotatable. BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 is a perspective view of an essential part showing a light stability test apparatus according to a first embodiment of the present invention.

FIG. 2 is a diagram showing a sensitivity distribution of a sensor for measuring an intermediate wavelength light beam in the light stability test apparatus according to the first embodiment of the present invention.

FIG. 3 is a perspective view of an essential part showing a light stability test apparatus according to a second embodiment of the present invention.

FIG. 4 is a main part front view showing a light stability test apparatus according to a conventional technique. FIG. 5 is a diagram showing a sensitivity distribution of a sensor for measuring visible light and ultraviolet light.

FIG. 6 is a diagram showing the degree of deterioration of menatrene.

FIG. 7 is a diagram showing the spectral distribution of sunlight, a xenon lamp, and a D65 lamp.

FIG. 8 is a diagram showing the transmittance of an ultraviolet filter. BEST MODE FOR CARRYING OUT THE INVENTION

The present invention will be described in more detail with reference to the accompanying drawings.

A light stability test apparatus according to a first embodiment of the present invention will be described with reference to FIGS. 1 and 2. FIG. 1 is a perspective view of a main part showing a light stability test apparatus according to a first embodiment of the present invention. FIG. 2 is a diagram showing a sensitivity distribution of a sensor for measuring an intermediate wavelength light beam in the light stability test apparatus according to the first embodiment of the present invention.

Reference numeral 4 denotes a sample stage, which is rotatable by a driving device 72 via a rotating shaft 71. On this sample table 4, three optical sensors are mounted. 5 is acceptable An eye ray measuring sensor, 6 is an ultraviolet ray measuring sensor, and 7 is an intermediate wavelength light ray measuring sensor. The visible light measuring sensor 5 has a sensitivity peak value around 5555 nm and mainly measures the irradiation amount of light in the visible light region. The ultraviolet measurement sensor 6 has a sensitivity peak value near 360 nm and mainly measures the irradiation amount of light in the ultraviolet region. The intermediate-wavelength light measurement sensor 7 has a sensitivity peak value near 400 nm, and mainly measures the irradiation amount of light in the intermediate-wavelength light region. In the present embodiment, an ultraviolet intensity meter having a light receiving unit of UD40 manufactured by Topcon Corporation is used as the intermediate-wavelength light measurement sensor 7. As shown in FIG. 2, this intermediate-wavelength light measurement sensor 7 has a sensitivity peak value near 400 nm. In FIG. 2, the horizontal axis represents the wavelength (unit: nm), and the vertical axis represents the relative value of each spectrum intensity.

Each of the sensors 5, 6, and 7 has a recording unit and a display unit (not shown) of the measured value and the integrated value measured by each sensor.

The other mechanical configurations such as the optical system in the light stability test apparatus are substantially the same as those in the related art.

Next, the operation and effect of the photostability test apparatus according to the first embodiment of the present invention having the above configuration will be described.

First, a sample (not shown) is placed on the sample table 4. Next, the light stability of the sample is tested by irradiating a sample (not shown) with a light beam emitted from a light source (not shown) via an optical system (not shown). During irradiation, the sample stage 4 is rotated by a driving device 72 via a rotation shaft 71 in order to make the irradiation distribution uniform.

During this light stability test, three sensors mounted on the sample stage 4, namely, the visible light measuring sensor 5, the ultraviolet light measuring sensor 6, and the intermediate wavelength light measuring sensor 7, detect visible light, ultraviolet light and Ray of light The instantaneous value of each dose and the integrated dose are recorded in a recording unit (not shown) and displayed on a display unit (not shown).

In the light stability test apparatus described above, the following experimental results were obtained for the light sources of sunlight, xenon light source and D65 light source.

Light source Visible light integrated value Ultraviolet light integrated value Intermediate wavelength integrated value Integration ratio Degree of deterioration

(k L xhr) (whr zm ² ) (whr / m ² ) (relative value) Sunlight 1 2 0 0 2 2 0 2 9 0 7 1.0.0 1 .0 0 Xenon light source 1 2 0 0 2 2 0 3 4 3 9 1.2 0 1.2 7 D 6 5 Light source 1 2 00 2 2 0 2 8 5 4 0.9.8 1.1 1 1 In the above table, the visible light integrated value, ultraviolet light integrated value and The intermediate wavelength integrated value is the integrated value of the irradiation amount of each light beam measured by the above-described visible light measuring sensor 5, ultraviolet light measuring sensor 6, and intermediate wavelength light measuring sensor 7, respectively. The integration ratio is a relative value when the intermediate wavelength integrated value of sunlight is 1.000. The degree of deterioration is a relative value when the degree of deterioration when sunlight is used as the light source is 1.0.

As shown in the above table, a large relationship is recognized between the intermediate wavelength integrated value and the degree of deterioration. As described above, not only the measurement value of the visible light measurement sensor 5 and the measurement value of the ultraviolet ray measurement sensor 6 but also the measurement value of the intermediate wavelength light measurement sensor 7 are displayed, so that the degree of deterioration of the sample can be more accurately and in detail. Can be displayed.

In this embodiment, the measured value of the intermediate-wavelength light measurement sensor 7 is displayed, but the signal from the intermediate-wavelength light measurement sensor 7 is transmitted to the control unit to control and adjust the optical system and the light source. It is also possible to do

Further, as an embodiment different from the optical sensor in the present embodiment, a further effect can be obtained by using a spectroradiometer. A spectroradiometer measures the entire area of the spectrum. For example, the measurement results are shown in Fig. 7, which shows the spectral distribution of sunlight, xenon lamps, and D65 lamps.

An index obtained by weighted averaging using the sensitivity coefficient (or weighted evaluation coefficient) of the sensor used in the stability test apparatus according to the first embodiment of the present invention can be used as the irradiation value. The data for each spectrum from the spectroradiometer is calculated by a microcomputer or the like, and the visible light integrated value, the ultraviolet light integrated value, and the intermediate wavelength integrated value are recorded and can be displayed on the display unit.

Specifically, the expression is as follows. UV energy 'E, = JV! , E 1 (E) d λ Ultraviolet energy: E ₂ = jv ₂ ; iE ₂ (λ) d λ Ultraviolet energy: E ₃ = JV ₃ .E 3 (λ) d λ

Here, E i (E), E 2 (λ), and Ε ₃ (λ) are integrated values for each spectrum. V, V 2 _λ and V 3 are weighted evaluation coefficients at each wavelength.

As described above, even if a spectroradiometer is used as the optical sensor, even if the agent has a large degree of deterioration in the intermediate wavelength region (400 ηπ! To 500 nm), accurate light stability can be obtained. A sex test can be performed.

As described above, the photostability test apparatus according to the present invention is capable of performing an accurate photostability test even for a drug having a large degree of deterioration in the intermediate wavelength region (400 nm to 500 nm). Can be.

Industrial potential

As described above, the light stability test apparatus according to the present invention includes a light source, an optical system that adjusts a light beam emitted from the light source, and a sample on which a sample irradiated with the light beam passing through the optical system is placed. Stage and the light beam attached to the sample stage In a light stability test apparatus having an optical sensor for measuring an irradiation amount, the optical sensor includes a visible light measuring sensor for measuring an irradiation amount of visible light, an ultraviolet measurement sensor for measuring an irradiation amount of ultraviolet light, and Since it has an intermediate-wavelength-light-measurement sensor that measures the amount of irradiation of intermediate-wavelength light between visible light and ultraviolet light, a drug with a large degree of deterioration in the intermediate-wavelength region (400 ηπ! ~ 500 nm) Even in this case, an accurate photostability test can be performed, which is useful for performing an accurate photostability test.

Claims

The scope of the claims

1. A light source, an optical system for adjusting the light emitted from the light source, a sample stage on which a sample to be irradiated with the light passing through the optical system is mounted, and an irradiation amount of the light beam attached to the sample stage is measured. A light stability test apparatus having an optical sensor for measuring the amount of visible light, a sensor for measuring visible light, an sensor for measuring ultraviolet light for measuring the amount of ultraviolet light, and a light sensor for measuring the amount of ultraviolet light. A light stability test apparatus comprising an intermediate wavelength ray measuring sensor for measuring the irradiation amount of the intermediate wavelength ray.

2. Light stability having a light source, a sample stage for mounting a sample to be irradiated with the light beam emitted from the light source, and an optical sensor attached to the sample stage for measuring the irradiation amount of the light beam. In the test apparatus, the optical sensor is a visible light measuring sensor for measuring the amount of visible light irradiation, an ultraviolet ray measuring sensor for measuring the amount of ultraviolet light irradiation, and measuring the irradiation amount of an intermediate wavelength light beam between visible light and ultraviolet light. A light stability test device comprising a sensor for measuring an intermediate wavelength light beam.

3. The light stability test apparatus according to claim 1, further comprising a measured value display section for displaying a measured value obtained by the intermediate-wavelength light measuring sensor.

4. The light stability test apparatus according to claim 3, wherein the measured value display section has an integrated value display section for displaying an integrated value obtained by integrating the measured values at each time point.

5. The light stability test apparatus according to claim 3 or 4, wherein the measured value display section has an instantaneous value display section for displaying an instantaneous value which is a measured value at each time point. .

6. A control unit for controlling the optical system by transmitting a signal from the intermediate wavelength light measurement sensor. The light stability test apparatus according to paragraph 1, paragraph 3, paragraph 4, or paragraph 5.

7. A control unit for controlling the light source by transmitting a signal from the sensor for measuring an intermediate wavelength light beam, wherein the control unit controls the light source. Item 7. The light stability test device according to item 5 or 6.

8. The sensor according to claim 1, wherein a peak sensitivity value of the sensor for measuring an intermediate wavelength light beam is in a range from 400 nm to 500 nm. Light stability test according to paragraph 4, paragraph 5, paragraph 6 or paragraph 7

9. The sensor according to claim 1, wherein the sensitivity peak value of the intermediate wavelength light measurement sensor is in a range from 450 nm to 470 nm. The light stability test apparatus according to paragraph 4, paragraph 5, paragraph 6, paragraph 7, paragraph 7, or paragraph 8.

10. The sensor according to claim 1, wherein the ultraviolet light measurement sensor has a sensitivity peak value in a range from 350 nm to 370 nm. The photostability test apparatus according to any one of paragraphs 5, 5, 6, 7, 8, and 9.

11. The claim 1, wherein the sensitivity peak value of the sensor for measuring visible light is in the range of 550 nm to 560 nm. Clause 5, Clause 6, Clause 7, Clause 7, Clause 8, Clause 9 or Clause 10, or the photostability test apparatus.

12. Light source, optical system for adjusting the light beam emitted from the light source, a sample stage on which a sample to be irradiated with the light beam passing through the optical system is mounted, and the irradiation amount of the light beam attached to the sample stage is determined. In a light stability test apparatus having an optical sensor for measurement, the optical sensor is a spectroradiometer, and the spectrum is evaluated from 400 nm to 500 nm for an intermediate wavelength light beam. The spectral distribution with the peak value of Characteristic light stability test equipment.

13 3. Light stability test including a light source, a sample stage on which a sample to be irradiated with the light beam emitted from the light source is mounted, and an optical sensor attached to the sample stage for measuring the irradiation amount of the light beam In the apparatus, the optical sensor is a spectroradiometer, and the spectrum is evaluated by weighting a spectrum distribution having a peak value of 400 nm to 500 nm for an intermediate wavelength light beam. A light stability test apparatus characterized by an evaluation coefficient.

14. The optical sensor is a spectroradiometer, and the spectrum is evaluated by using a spectrum distribution having a peak value of 450 nm to 470 nm for an intermediate wavelength light beam. The light stability test apparatus according to claim 12 or 13, wherein the light stability test apparatus is a weighted evaluation coefficient.

15 5. The light sensor is a spectroradiometer, and the spectrum is evaluated. For ultraviolet rays, a spectrum distribution with a peak value of 35 O nm to 37 O nm is weighted. The Mitsuyasu qualitative test apparatus according to claim 12, characterized in that it is an evaluation coefficient.

16. The optical sensor is a spectroradiometer, and the spectrum is evaluated by using a spectrum distribution having a peak value of 55 nm to 560 nm for visible light. 16. The light stability test apparatus according to claim 12, wherein the light stability test apparatus is a weighted evaluation coefficient.

17. A measurement value display section for displaying a measurement value of an irradiation amount of an intermediate-wavelength light beam by the spectrum mouth radiometer, wherein the measurement value display section displays a measurement value display section. Light stability test equipment described in Paragraph 4, 15 or 16

18. The light stability test apparatus according to claim 17, wherein the measured value display section has an integrated value display section for displaying an integrated value obtained by integrating the measured values at each time point. .

19. The measurement value display section according to claim 17, wherein the measurement value display section has an instantaneous value display section for displaying an instantaneous value which is a measurement value at each time point. Light stability test equipment.

20. A control unit for controlling the optical system by transmitting a signal of a measured value of an irradiation amount of an intermediate wavelength light beam by the spectroradiometer, wherein the control unit controls the optical system. 14. The photostability test apparatus according to paragraph 14, paragraph 15, paragraph 16, paragraph 18, paragraph 19 or paragraph 19.

21. A control device for controlling the light source by transmitting a signal from the sensor for measuring an intermediate wavelength light beam, wherein the control unit controls the light source. Clause 16, Clause 17, Clause 17, Clause 18, Clause 19, or Clause 20.

2 2. The sample stage, wherein the sample stage is rotatable. Claims 1, 2, 3, 3, 4, 5, 6, 7, 8 Section 8, Section 9, Section 10, Section 11, Section 12, Section 13, Section 14, Section 15, Section 16, Section 17, Section 17, Section 18 Item 18. The light stability test apparatus according to Item 19, Item 20 or Item 21.