WO2003001215A3 - Ventilblock für eine anordnung von kolbenpipetten - Google Patents

Ventilblock für eine anordnung von kolbenpipetten Download PDF

Info

Publication number
WO2003001215A3
WO2003001215A3 PCT/CH2002/000306 CH0200306W WO03001215A3 WO 2003001215 A3 WO2003001215 A3 WO 2003001215A3 CH 0200306 W CH0200306 W CH 0200306W WO 03001215 A3 WO03001215 A3 WO 03001215A3
Authority
WO
WIPO (PCT)
Prior art keywords
valve block
arrangement
plates
pattern
holes
Prior art date
Application number
PCT/CH2002/000306
Other languages
English (en)
French (fr)
Other versions
WO2003001215A2 (de
Inventor
Ernst Buergisser
Original Assignee
Epr Labautomation Ag
Ernst Buergisser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epr Labautomation Ag, Ernst Buergisser filed Critical Epr Labautomation Ag
Priority to EP02732306A priority Critical patent/EP1399745A2/de
Priority to US10/481,803 priority patent/US7073531B2/en
Priority to AU2002304953A priority patent/AU2002304953A1/en
Publication of WO2003001215A2 publication Critical patent/WO2003001215A2/de
Publication of WO2003001215A3 publication Critical patent/WO2003001215A3/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0265Drop counters; Drop formers using valves to interrupt or meter fluid flow, e.g. using solenoids or metering valves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K99/0001Microvalves
    • F16K99/0003Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0011Gate valves or sliding valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00783Laminate assemblies, i.e. the reactor comprising a stack of plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00851Additional features
    • B01J2219/00871Modular assembly
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781Aspects relating to microreactors
    • B01J2219/00891Feeding or evacuation
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0073Fabrication methods specifically adapted for microvalves
    • F16K2099/0076Fabrication methods specifically adapted for microvalves using electrical discharge machining [EDM], milling or drilling
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0073Fabrication methods specifically adapted for microvalves
    • F16K2099/008Multi-layer fabrications
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16KVALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00Subject matter not provided for in other groups of this subclass
    • F16K2099/0082Microvalves adapted for a particular use
    • F16K2099/0084Chemistry or biology, e.g. "lab-on-a-chip" technology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00237Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G01N2035/00247Microvalves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N35/1074Multiple transfer devices arranged in a two-dimensional array
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/86493Multi-way valve unit
    • Y10T137/86879Reciprocating valve unit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/87249Multiple inlet with multiple outlet
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00Fluid handling
    • Y10T137/8593Systems
    • Y10T137/87917Flow path with serial valves and/or closures

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Fluid Mechanics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Ein Ventilblock (1) für eine Dosiervorrichtung mit einer Anordnung von Kolbenpipetten (2) oder anderen Dosiermitteln weist auf seiner einen Seite ein auf die Anordnung von Kolbenpipetten (2) ausrichtbares Muster von ersten Mündungen (15) und auf der gegenüberliegenden Seite je einer ersten Mündung (15) zugeordnete zweite Mündungen (16) auf. Ferner weist der Ventilblock (1) eine Mehrzahl von Kanalsystemen (20) mit je einem Hauptanschluss (23) auf. Der Ventilblock (1) besteht im wesentlichen aus einer Mehrzahl von in einem Stapel angeordneten Platten (10, 11, 12, 13). Alle Platten weisen durchgehende Öffnungen (14) auf, die im Muster der ersten Mündungen (15) angeordnet sind. Mindestens ein Teil der Platten (11, 12, 13) weist zusätzlich je ein Kanalsystem (20) mit Kanälen (21), die mit dem Hautanschluss (23) verbunden sind, auf, wobei die Kanäle (21) ein Muster bilden, das auf das Muster der durchgehenden Öffnungen (14) abgestimmt und gegenüber diesem lateral verschoben ist. Zur wahlweisen Verbindung der ersten Mündungen (15) mit je der zugeordneten zweiten Mündung (16) oder mit einem ausgewählten Kanalsystem (20) werden die Platten (11, 12, 13) mit Kanalsystem wahlweise lateral verschoben.
PCT/CH2002/000306 2001-06-26 2002-06-10 Ventilblock für eine anordnung von kolbenpipetten WO2003001215A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02732306A EP1399745A2 (de) 2001-06-26 2002-06-10 Ventilblock für eine anordnung von kolbenpipetten
US10/481,803 US7073531B2 (en) 2001-06-26 2002-06-10 Valve block
AU2002304953A AU2002304953A1 (en) 2001-06-26 2002-06-10 Valve block for an arrangement of piston pipettes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH11712001 2001-06-26
CH1171/01 2001-06-26

Publications (2)

Publication Number Publication Date
WO2003001215A2 WO2003001215A2 (de) 2003-01-03
WO2003001215A3 true WO2003001215A3 (de) 2003-06-26

Family

ID=4561256

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CH2002/000306 WO2003001215A2 (de) 2001-06-26 2002-06-10 Ventilblock für eine anordnung von kolbenpipetten

Country Status (4)

Country Link
US (1) US7073531B2 (de)
EP (1) EP1399745A2 (de)
AU (1) AU2002304953A1 (de)
WO (1) WO2003001215A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11035480B2 (en) 2016-02-24 2021-06-15 Leanna Levine and Aline, Inc. Mechanically driven sequencing manifold
EP4075222A1 (de) * 2016-02-24 2022-10-19 Leanna Levine Mechanisch angetriebener sequenzverteiler
IL307492A (en) * 2021-04-12 2023-12-01 Octane Biotech Inc Combinatorial liquid switch for use in automated cell engineering systems

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137698A (en) * 1988-04-22 1992-08-11 Europaisches Laboratorium fur Molekularbiologic (EMBL) Apparatus for carrying out chemical reaction sequences
US5538694A (en) * 1992-03-02 1996-07-23 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Device for simultaneously or sequentially carrying out chemical reactions
WO1998057738A1 (de) * 1997-06-16 1998-12-23 Chemspeed Ltd. Vorrichtung zur parallelen durchführung einer vielzahl von chemischen, biochemischen oder physikalischen verfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2904070A (en) * 1955-06-06 1959-09-15 Ibm Multi-port selector
US2857082A (en) * 1957-04-19 1958-10-21 Nat Equip Corp Pump construction for candy depositing machines
FR1586152A (de) * 1968-07-26 1970-02-13

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137698A (en) * 1988-04-22 1992-08-11 Europaisches Laboratorium fur Molekularbiologic (EMBL) Apparatus for carrying out chemical reaction sequences
US5538694A (en) * 1992-03-02 1996-07-23 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Device for simultaneously or sequentially carrying out chemical reactions
WO1998057738A1 (de) * 1997-06-16 1998-12-23 Chemspeed Ltd. Vorrichtung zur parallelen durchführung einer vielzahl von chemischen, biochemischen oder physikalischen verfahren

Also Published As

Publication number Publication date
US7073531B2 (en) 2006-07-11
US20040112441A1 (en) 2004-06-17
AU2002304953A1 (en) 2003-01-08
EP1399745A2 (de) 2004-03-24
WO2003001215A2 (de) 2003-01-03

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