WO2002100436A3 - Ophthalmic once-a-day composition - Google Patents

Ophthalmic once-a-day composition Download PDF

Info

Publication number
WO2002100436A3
WO2002100436A3 PCT/EP2002/006282 EP0206282W WO02100436A3 WO 2002100436 A3 WO2002100436 A3 WO 2002100436A3 EP 0206282 W EP0206282 W EP 0206282W WO 02100436 A3 WO02100436 A3 WO 02100436A3
Authority
WO
WIPO (PCT)
Prior art keywords
ophthalmic
once
polymer
day composition
composition
Prior art date
Application number
PCT/EP2002/006282
Other languages
French (fr)
Other versions
WO2002100436A2 (en
Inventor
Saunier Maggy Babiole
Jean-Claude Bizec
Andrea Fetz
Christian Schoch
Original Assignee
Novartis Ag
Novartis Pharma Gmbh
Saunier Maggy Babiole
Jean-Claude Bizec
Andrea Fetz
Christian Schoch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Pharma Gmbh, Saunier Maggy Babiole, Jean-Claude Bizec, Andrea Fetz, Christian Schoch filed Critical Novartis Ag
Priority to AU2002345015A priority Critical patent/AU2002345015A1/en
Publication of WO2002100436A2 publication Critical patent/WO2002100436A2/en
Publication of WO2002100436A3 publication Critical patent/WO2002100436A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention is directed to an ophthalmic composition adapted for topical once-a-day administration to the eye comprising an ophthalmic drug, in particular to an ophthalmic composition comprising an ophthalmic drug and at least one polymer selected from one or more of i) a polyoxyethylene-polyoxypropylene co-polymer or block co-polymer, and ii) a cross-linked acrylic acid polymer.
PCT/EP2002/006282 2001-06-08 2002-06-07 Ophthalmic once-a-day composition WO2002100436A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002345015A AU2002345015A1 (en) 2001-06-08 2002-06-07 Ophthalmic once-a-day composition

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP01113960.7 2001-06-08
EP01113957 2001-06-08
EP01113960 2001-06-08
EP01113957.3 2001-06-08

Publications (2)

Publication Number Publication Date
WO2002100436A2 WO2002100436A2 (en) 2002-12-19
WO2002100436A3 true WO2002100436A3 (en) 2003-09-25

Family

ID=26076610

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/006282 WO2002100436A2 (en) 2001-06-08 2002-06-07 Ophthalmic once-a-day composition

Country Status (2)

Country Link
AU (1) AU2002345015A1 (en)
WO (1) WO2002100436A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
US20070077303A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for providing oxidatively stable ophthalmic compositions
ITRM20050547A1 (en) * 2005-11-04 2007-05-05 Sooft Italia S R L OPHTHALMIC GEL COMPOSED OF TRIAMCINOLONE ACETONIDE AND A POLYCRYLIC POLYMER.

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0487729A1 (en) * 1989-08-18 1992-06-03 Hisamitsu Pharmaceutical Co., Inc. Ketotifen preparation for external use
EP0551626A1 (en) * 1991-12-19 1993-07-21 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
WO1998052579A1 (en) * 1997-05-23 1998-11-26 Insite Vision Incorporated Ophthalmic compositions containing a divalent salt and a non steroidal anti-inflammatory drugs as a precipitate
WO1999036055A1 (en) * 1998-01-15 1999-07-22 Novartis Ag Autoclavable pharmaceutical compositions containing a chelating agent
WO1999051230A1 (en) * 1998-04-02 1999-10-14 Novartis Ag Method for stabilizing pharmaceutical compositions by special use of an antioxidant
WO2001007049A2 (en) * 1999-07-23 2001-02-01 Novartis Ag Ophthalmic composition comprising ketotifen
WO2002100376A1 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic compositions comprising chitosan and an active substance, in particular ketotifen, and use thereof for the treatment of ocular allergic conditions
WO2002100437A2 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic compositions comprising hyaluronic acid

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0487729A1 (en) * 1989-08-18 1992-06-03 Hisamitsu Pharmaceutical Co., Inc. Ketotifen preparation for external use
EP0551626A1 (en) * 1991-12-19 1993-07-21 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
WO1998052579A1 (en) * 1997-05-23 1998-11-26 Insite Vision Incorporated Ophthalmic compositions containing a divalent salt and a non steroidal anti-inflammatory drugs as a precipitate
WO1999036055A1 (en) * 1998-01-15 1999-07-22 Novartis Ag Autoclavable pharmaceutical compositions containing a chelating agent
WO1999051230A1 (en) * 1998-04-02 1999-10-14 Novartis Ag Method for stabilizing pharmaceutical compositions by special use of an antioxidant
WO2001007049A2 (en) * 1999-07-23 2001-02-01 Novartis Ag Ophthalmic composition comprising ketotifen
WO2002100376A1 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic compositions comprising chitosan and an active substance, in particular ketotifen, and use thereof for the treatment of ocular allergic conditions
WO2002100437A2 (en) * 2001-06-08 2002-12-19 Novartis Ag Ophthalmic compositions comprising hyaluronic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LIN HONG-RU ET AL: "Carbopol/pluronic phase change solutions for ophthalmic drug delivery.", JOURNAL OF CONTROLLED RELEASE, vol. 69, no. 3, 2000, pages 379 - 388, XP004221288, ISSN: 0168-3659 *

Also Published As

Publication number Publication date
WO2002100436A2 (en) 2002-12-19
AU2002345015A1 (en) 2002-12-23

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