WO2002097066A3 - Human vascular progenitor cells - Google Patents

Human vascular progenitor cells Download PDF

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Publication number
WO2002097066A3
WO2002097066A3 PCT/IT2002/000347 IT0200347W WO02097066A3 WO 2002097066 A3 WO2002097066 A3 WO 2002097066A3 IT 0200347 W IT0200347 W IT 0200347W WO 02097066 A3 WO02097066 A3 WO 02097066A3
Authority
WO
WIPO (PCT)
Prior art keywords
progenitor cells
human vascular
vascular progenitor
human
obtainable
Prior art date
Application number
PCT/IT2002/000347
Other languages
French (fr)
Other versions
WO2002097066A2 (en
WO2002097066A8 (en
Inventor
Giulio Alessandri
Arnaldo Caruso
Jose Sebastian Franzone
Original Assignee
Medestea Internaz S R L
Giulio Alessandri
Arnaldo Caruso
Jose Sebastian Franzone
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medestea Internaz S R L, Giulio Alessandri, Arnaldo Caruso, Jose Sebastian Franzone filed Critical Medestea Internaz S R L
Priority to AU2002314526A priority Critical patent/AU2002314526A1/en
Publication of WO2002097066A2 publication Critical patent/WO2002097066A2/en
Publication of WO2002097066A8 publication Critical patent/WO2002097066A8/en
Publication of WO2002097066A3 publication Critical patent/WO2002097066A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0692—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to human CD34+CD31- vascular progenitor cells which are obtainable from human foetal aorta explants and which are capable of forming new vascular structures in vitro by culture in a three-dimensional collagen matrix.
PCT/IT2002/000347 2001-05-31 2002-05-30 Human vascular progenitor cells WO2002097066A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002314526A AU2002314526A1 (en) 2001-05-31 2002-05-30 Human vascular progenitor cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001TO000517A ITTO20010517A1 (en) 2001-05-31 2001-05-31 HUMAN VASCULAR PROGENITRIC CELLS.
ITTO2001A000517 2001-05-31

Publications (3)

Publication Number Publication Date
WO2002097066A2 WO2002097066A2 (en) 2002-12-05
WO2002097066A8 WO2002097066A8 (en) 2003-03-13
WO2002097066A3 true WO2002097066A3 (en) 2003-09-25

Family

ID=11458912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2002/000347 WO2002097066A2 (en) 2001-05-31 2002-05-30 Human vascular progenitor cells

Country Status (3)

Country Link
AU (1) AU2002314526A1 (en)
IT (1) ITTO20010517A1 (en)
WO (1) WO2002097066A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008509678A (en) * 2004-08-13 2008-04-03 メドトロニック・インコーポレーテッド Isolation of endothelial progenitor cell subsets and methods for their use
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
PT1951864E (en) 2005-11-07 2014-08-27 Amorcyte Inc Compositions and methods of vascular injury repair
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
WO2007093412A2 (en) 2006-02-16 2007-08-23 Fondazione Centro San Raffaele Del Monte Tabor Skeletal muscle periangioblasts and cardiac mesoangioblasts, method for isolation and uses thereof
TW200817019A (en) * 2006-07-10 2008-04-16 Univ Columbia De novo formation and regeneration of vascularized tissue from tissue progenitor cells and vascular progenitor cells
US20100028311A1 (en) * 2008-07-09 2010-02-04 Baxter International Inc. Using of scaffold comprising fibrin for delivery of stem cells
CA2743255C (en) 2008-12-03 2014-02-18 Andrew Pecora Infarct area perfusion-improving compositions and methods of vascular injury repair

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALESSANDRI GIOLIO ET AL: "Outgrowth of branching microvessels from human fetal aorta explants in vitro: An angiogenesis and vasculogenesis process.", PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH ANNUAL, no. 41, March 2000 (2000-03-01), 91st Annual Meeting of the American Association for Cancer Research.;San Francisco, California, USA; April 01-05, 2000, March, 2000, pages 650, XP002227165, ISSN: 0197-016X *
ALESSANDRI GIULIO ET AL: "Human vasculogenesis ex vivo: Embryonal aorta as a tool for isolation of endothelial cell progenitors.", LABORATORY INVESTIGATION, vol. 81, no. 6, June 2001 (2001-06-01), pages 875 - 885, XP002227166, ISSN: 0023-6837 *
ALESSANDRI GIULIO ET AL: "Isolation of vascular progenitors from human embryonal aorta.", JOURNAL OF HUMAN VIROLOGY, vol. 4, no. 3, May 2001 (2001-05-01), 2001 International Meeting of the Institute of Human Virology;Baltimore, Maryland, USA; September 09-13, 2001, pages 146, XP001122836, ISSN: 1090-9508 *
GIRELLI M ET AL: "Human embryonic endothelial cells: a new tool for therapeutical approach in neurological disorders?", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 26, no. 1-2, 2000, 30th Annual Meeting of the Society of Neuroscience;New Orleans, LA, USA; November 04-09, 2000, pages Abstract No. - 327.14, XP001109455, ISSN: 0190-5295 *
HEWETT P W ET AL: "Human lung microvessel endothelial cells: Isolation, culture, and characterization.", MICROVASCULAR RESEARCH, vol. 46, no. 1, 1993, pages 89 - 102, XP008012295, ISSN: 0026-2862 *
MASUDA H ET AL: "Endothelial progenitor cells for regeneration.", HUMAN CELL: OFFICIAL JOURNAL OF HUMAN CELL RESEARCH SOCIETY. JAPAN DEC 2000, vol. 13, no. 4, December 2000 (2000-12-01), pages 153 - 160, XP001133828, ISSN: 0914-7470 *

Also Published As

Publication number Publication date
WO2002097066A2 (en) 2002-12-05
WO2002097066A8 (en) 2003-03-13
ITTO20010517A1 (en) 2002-12-01
AU2002314526A1 (en) 2002-12-09
ITTO20010517A0 (en) 2001-05-31

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