WO2002090504A3 - Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use - Google Patents

Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use Download PDF

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Publication number
WO2002090504A3
WO2002090504A3 PCT/US2002/014342 US0214342W WO02090504A3 WO 2002090504 A3 WO2002090504 A3 WO 2002090504A3 US 0214342 W US0214342 W US 0214342W WO 02090504 A3 WO02090504 A3 WO 02090504A3
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WO
WIPO (PCT)
Prior art keywords
bind
nucleic acids
methods
antigens
acids encoding
Prior art date
Application number
PCT/US2002/014342
Other languages
French (fr)
Other versions
WO2002090504A2 (en
Inventor
John P Ii Alsobrook
David W Anderson
Ferenc L Boldog
Catherine E Burgess
Stacie J Casman
Original Assignee
Curagen Corp
John P Ii Alsobrook
David W Anderson
Ferenc L Boldog
Catherine E Burgess
Stacie J Casman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/138,588 external-priority patent/US20040018594A1/en
Application filed by Curagen Corp, John P Ii Alsobrook, David W Anderson, Ferenc L Boldog, Catherine E Burgess, Stacie J Casman filed Critical Curagen Corp
Priority to EP02741693A priority Critical patent/EP1463747A2/en
Priority to JP2002587567A priority patent/JP2005506054A/en
Priority to CA002446437A priority patent/CA2446437A1/en
Publication of WO2002090504A2 publication Critical patent/WO2002090504A2/en
Publication of WO2002090504A3 publication Critical patent/WO2002090504A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
PCT/US2002/014342 2001-05-03 2002-05-02 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use WO2002090504A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02741693A EP1463747A2 (en) 2001-05-03 2002-05-02 Novel antibodies that bind to antigenic polypeptides,nucleic acids encodings the antigens, and methodes of use
JP2002587567A JP2005506054A (en) 2001-05-03 2002-05-02 Novel antibodies that bind to antigenic therapeutic polypeptides, nucleic acids encoding antigens, and methods of use
CA002446437A CA2446437A1 (en) 2001-05-03 2002-05-02 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use

Applications Claiming Priority (54)

Application Number Priority Date Filing Date Title
US28839501P 2001-05-03 2001-05-03
US60/288,395 2001-05-03
US28890001P 2001-05-04 2001-05-04
US60/288,900 2001-05-04
US28908701P 2001-05-07 2001-05-07
US60/289,087 2001-05-07
US29075301P 2001-05-14 2001-05-14
US60/290,753 2001-05-14
US29118901P 2001-05-15 2001-05-15
US60/291,189 2001-05-15
US29124301P 2001-05-16 2001-05-16
US60/291,243 2001-05-16
US29200101P 2001-05-18 2001-05-18
US60/292,001 2001-05-18
US29237401P 2001-05-21 2001-05-21
US60/292,374 2001-05-21
US29258701P 2001-05-22 2001-05-22
US60/292,587 2001-05-22
US29310701P 2001-05-23 2001-05-23
US60/293,107 2001-05-23
US29411001P 2001-05-29 2001-05-29
US60/294,110 2001-05-29
US29443401P 2001-05-30 2001-05-30
US60/294,434 2001-05-30
US29482701P 2001-05-31 2001-05-31
US60/294,827 2001-05-31
US29898801P 2001-06-18 2001-06-18
US60/298,988 2001-06-18
US30890101P 2001-07-31 2001-07-31
US60/308,901 2001-07-31
US31338801P 2001-08-17 2001-08-17
US60/313,388 2001-08-17
US31393701P 2001-08-21 2001-08-21
US31385101P 2001-08-21 2001-08-21
US60/313,937 2001-08-21
US60/313,851 2001-08-21
US32280201P 2001-09-17 2001-09-17
US32270101P 2001-09-17 2001-09-17
US60/322,802 2001-09-17
US60,322,701 2001-09-17
US32475701P 2001-09-25 2001-09-25
US60/324,757 2001-09-25
US32568201P 2001-09-27 2001-09-27
US32531401P 2001-09-27 2001-09-27
US60/325,682 2001-09-27
US60/325,314 2001-09-27
US33212901P 2001-11-21 2001-11-21
US60/332,129 2001-11-21
US33688201P 2001-12-03 2001-12-03
US60/336,882 2001-12-03
US34030501P 2001-12-14 2001-12-14
US60/340,305 2001-12-14
US10/138,588 US20040018594A1 (en) 2001-05-03 2002-05-01 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
US10/138,588 2002-05-01

Publications (2)

Publication Number Publication Date
WO2002090504A2 WO2002090504A2 (en) 2002-11-14
WO2002090504A3 true WO2002090504A3 (en) 2004-08-12

Family

ID=27586816

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/014342 WO2002090504A2 (en) 2001-05-03 2002-05-02 Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use

Country Status (4)

Country Link
EP (1) EP1463747A2 (en)
JP (1) JP2005506054A (en)
CA (1) CA2446437A1 (en)
WO (1) WO2002090504A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6277972B1 (en) 1998-08-10 2001-08-21 Urogenesys, Inc. BPC-1: a secreted brain-specific protein expressed and secreted by prostate and bladder cancer cells
EP1659177A3 (en) * 2000-06-02 2006-05-31 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids ancoding the same
US7157558B2 (en) 2001-06-01 2007-01-02 Genentech, Inc. Polypeptide encoded by a polynucleotide overexpresses in tumors
AU2002327176A1 (en) * 2001-06-06 2002-12-16 Human Genome Sciences, Inc. 20 human secreted proteins
US7141381B2 (en) 2002-04-25 2006-11-28 Bristol-Myers Squibb Company Human leucine-rich repeat-containing proteins specifically expressed in the nervous system
EP2633884A1 (en) * 2010-01-07 2013-09-04 Akron Molecules GmbH Obesity small molecules
JP2020531047A (en) * 2017-08-16 2020-11-05 エッレジヴ１・ソチエタ・ア・レスポンサビリタ・リミタータ VTFT isoform of BPIFB4 protein for use in neurological disorders and nerve injuries

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942417A (en) * 1996-07-15 1999-08-24 Human Genome Sciences, Inc. CD44-like protein and nucleic acids
US6368794B1 (en) * 1999-01-15 2002-04-09 Incyte Genomics, Inc. Detection of altered expression of genes regulating cell proliferation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942417A (en) * 1996-07-15 1999-08-24 Human Genome Sciences, Inc. CD44-like protein and nucleic acids
US6368794B1 (en) * 1999-01-15 2002-04-09 Incyte Genomics, Inc. Detection of altered expression of genes regulating cell proliferation

Also Published As

Publication number Publication date
WO2002090504A2 (en) 2002-11-14
CA2446437A1 (en) 2002-11-14
EP1463747A2 (en) 2004-10-06
JP2005506054A (en) 2005-03-03

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