WO2002083883A3 - Human phosphodiesterase 9a isoform - Google Patents

Human phosphodiesterase 9a isoform Download PDF

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Publication number
WO2002083883A3
WO2002083883A3 PCT/EP2002/003898 EP0203898W WO02083883A3 WO 2002083883 A3 WO2002083883 A3 WO 2002083883A3 EP 0203898 W EP0203898 W EP 0203898W WO 02083883 A3 WO02083883 A3 WO 02083883A3
Authority
WO
WIPO (PCT)
Prior art keywords
isoform
human phosphodiesterase
phosphodiesterase
pde9a5
human
Prior art date
Application number
PCT/EP2002/003898
Other languages
French (fr)
Other versions
WO2002083883A2 (en
Inventor
Armin Hatzelmann
Gianluca Quintini
Wolfram Steinhilber
Original Assignee
Altana Pharma Ag
Armin Hatzelmann
Gianluca Quintini
Wolfram Steinhilber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag, Armin Hatzelmann, Gianluca Quintini, Wolfram Steinhilber filed Critical Altana Pharma Ag
Priority to AU2002312801A priority Critical patent/AU2002312801A1/en
Publication of WO2002083883A2 publication Critical patent/WO2002083883A2/en
Publication of WO2002083883A3 publication Critical patent/WO2002083883A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Abstract

The invention provides human phosphodiesterase PDE9A5 and polynucleotides which encode PDE9A5.
PCT/EP2002/003898 2001-04-11 2002-04-09 Human phosphodiesterase 9a isoform WO2002083883A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002312801A AU2002312801A1 (en) 2001-04-11 2002-04-09 Human phosphodiesterase 9a isoform

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01108981.0 2001-04-11
EP01108981 2001-04-11

Publications (2)

Publication Number Publication Date
WO2002083883A2 WO2002083883A2 (en) 2002-10-24
WO2002083883A3 true WO2002083883A3 (en) 2003-04-17

Family

ID=8177109

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/003898 WO2002083883A2 (en) 2001-04-11 2002-04-09 Human phosphodiesterase 9a isoform

Country Status (2)

Country Link
AU (1) AU2002312801A1 (en)
WO (1) WO2002083883A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029873A1 (en) * 1997-12-09 1999-06-17 Incyte Pharmaceuticals, Inc. Cyclic gmp phosphodiesterase
WO1999042596A2 (en) * 1998-02-23 1999-08-26 Icos Corporation Phosphodiesterase 10

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029873A1 (en) * 1997-12-09 1999-06-17 Incyte Pharmaceuticals, Inc. Cyclic gmp phosphodiesterase
WO1999042596A2 (en) * 1998-02-23 1999-08-26 Icos Corporation Phosphodiesterase 10

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DOUSA T P: "Cyclic-3',5'-nucleotide phosphodiesterase isozymes in cell biology and pathophysiology of the kidney.", KIDNEY INTERNATIONAL, (1999 JAN) 55 (1) 29-62. REF: 232, XP002169142 *
FISHER D A ET AL: "Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase", JOURNAL OF BIOLOGICAL CHEMISTRY,US,AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, vol. 273, no. 25, 19 June 1998 (1998-06-19), pages 15559 - 15564, XP002091363, ISSN: 0021-9258 *
GUIPPONI MICHEL ET AL: "Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: Alternative splicing of mRNA transcripts, genomic structure and sequence.", HUMAN GENETICS, vol. 103, no. 4, October 1998 (1998-10-01), pages 386 - 392, XP001000997, ISSN: 0340-6717 *

Also Published As

Publication number Publication date
AU2002312801A1 (en) 2002-10-28
WO2002083883A2 (en) 2002-10-24

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