WO2002083294A3 - Chemical libraries based on coded particles - Google Patents

Chemical libraries based on coded particles Download PDF

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Publication number
WO2002083294A3
WO2002083294A3 PCT/GB2002/001792 GB0201792W WO02083294A3 WO 2002083294 A3 WO2002083294 A3 WO 2002083294A3 GB 0201792 W GB0201792 W GB 0201792W WO 02083294 A3 WO02083294 A3 WO 02083294A3
Authority
WO
WIPO (PCT)
Prior art keywords
chemical libraries
library
libraries based
coded particles
particles
Prior art date
Application number
PCT/GB2002/001792
Other languages
French (fr)
Other versions
WO2002083294A2 (en
Inventor
Susan Louise Watson
Amit Kumar Som
Nigel Guy Skinner
Stephen Henry Chambers
Original Assignee
3 D Molecular Sciences Ltd
Susan Louise Watson
Amit Kumar Som
Nigel Guy Skinner
Stephen Henry Chambers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 D Molecular Sciences Ltd, Susan Louise Watson, Amit Kumar Som, Nigel Guy Skinner, Stephen Henry Chambers filed Critical 3 D Molecular Sciences Ltd
Priority to AU2002249427A priority Critical patent/AU2002249427A1/en
Publication of WO2002083294A2 publication Critical patent/WO2002083294A2/en
Publication of WO2002083294A3 publication Critical patent/WO2002083294A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00502—Particles of irregular geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00542—Alphanumeric characters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/0056—Raised or sunken areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The chemical library, and a method of making said library, comprising particles each having thereon a respective chemical member of said library, each particle having markings serving to identify the particle, and thereby to identify the chemical member of the library on any selected particle, wherein said particles each comprise a fluorescent material which has been selectively bleached at selected locations to define said markings.
PCT/GB2002/001792 2001-04-18 2002-04-18 Chemical libraries based on coded particles WO2002083294A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002249427A AU2002249427A1 (en) 2001-04-18 2002-04-18 Chemical libraries based on coded particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0109544A GB0109544D0 (en) 2001-04-18 2001-04-18 Chemical libraries based on coded particles
GB0109544.7 2001-04-18

Publications (2)

Publication Number Publication Date
WO2002083294A2 WO2002083294A2 (en) 2002-10-24
WO2002083294A3 true WO2002083294A3 (en) 2003-01-16

Family

ID=9913002

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/001792 WO2002083294A2 (en) 2001-04-18 2002-04-18 Chemical libraries based on coded particles

Country Status (3)

Country Link
AU (1) AU2002249427A1 (en)
GB (1) GB0109544D0 (en)
WO (1) WO2002083294A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111470D0 (en) * 2001-05-10 2001-07-04 Scient Generics Ltd Homogenous photoresist functionalisation

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05278319A (en) * 1992-03-31 1993-10-26 Toppan Printing Co Ltd Sign panel and card using the same
GB2334347A (en) * 1998-02-13 1999-08-18 Univ Hertfordshire Method of fabricating coded particles
WO2000063695A1 (en) * 1999-04-16 2000-10-26 Tibotec N.V. Encoding of microcarriers
WO2001006505A1 (en) * 1999-07-15 2001-01-25 Trid Store Ip, L.L.C. Multilayer fluorescent optical disc with photosensitive fluorescent material
WO2001078889A2 (en) * 2000-04-19 2001-10-25 3D Molecular Sciences Limited A method of fabricating coded particles

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05278319A (en) * 1992-03-31 1993-10-26 Toppan Printing Co Ltd Sign panel and card using the same
GB2334347A (en) * 1998-02-13 1999-08-18 Univ Hertfordshire Method of fabricating coded particles
WO2000063695A1 (en) * 1999-04-16 2000-10-26 Tibotec N.V. Encoding of microcarriers
WO2001006505A1 (en) * 1999-07-15 2001-01-25 Trid Store Ip, L.L.C. Multilayer fluorescent optical disc with photosensitive fluorescent material
WO2001078889A2 (en) * 2000-04-19 2001-10-25 3D Molecular Sciences Limited A method of fabricating coded particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199347, Derwent World Patents Index; Class A97, AN 1993-374212, XP002220550 *
PATENT ABSTRACTS OF JAPAN vol. 018, no. 055 (M - 1550) 28 January 1994 (1994-01-28) *

Also Published As

Publication number Publication date
WO2002083294A2 (en) 2002-10-24
AU2002249427A1 (en) 2002-10-28
GB0109544D0 (en) 2001-06-06

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