WO2002081676A3 - Nichtpathogener bakterieller rezipientenstamm eines mycolsäure-haltigen bakteriums, verfahren zu dessen herstellung und dessen verwendung - Google Patents

Nichtpathogener bakterieller rezipientenstamm eines mycolsäure-haltigen bakteriums, verfahren zu dessen herstellung und dessen verwendung Download PDF

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Publication number
WO2002081676A3
WO2002081676A3 PCT/EP2002/003733 EP0203733W WO02081676A3 WO 2002081676 A3 WO2002081676 A3 WO 2002081676A3 EP 0203733 W EP0203733 W EP 0203733W WO 02081676 A3 WO02081676 A3 WO 02081676A3
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WO
WIPO (PCT)
Prior art keywords
mycolic acid
bacterium containing
containing mycolic
recipient strain
production
Prior art date
Application number
PCT/EP2002/003733
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English (en)
French (fr)
Other versions
WO2002081676A2 (de
Inventor
Michael Niederweis
Original Assignee
Michael Niederweis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Niederweis filed Critical Michael Niederweis
Priority to AU2002316837A priority Critical patent/AU2002316837A1/en
Publication of WO2002081676A2 publication Critical patent/WO2002081676A2/de
Publication of WO2002081676A3 publication Critical patent/WO2002081676A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Die vorliegende Erfindung betrifft einen nichtpathogenen und/oder schnell wachsenden bakteriellen Poringen-Rezipientenstamm eines Mycolsäure-haltigen Bakteriums, der für mindestens ein inaktiviertes Porin-Gen durch mindestens ein entsprechendes Porin-Gen aus einem pathogenen und/oder langsam wachsenden Mycolsäure-haltigen Bakterium transgen ist. Weiterhin betrifft die Erfindung ein Verfahren zur Herstellung eines solchen erfindungsgemäßen bakteriellen Rezipientenstammes und seine Verwendung zur Identifizierung von antibakteriell wirkenden Substanzen gegen pathogene Mycolsäure-haltige Bakterien.
PCT/EP2002/003733 2001-04-04 2002-04-04 Nichtpathogener bakterieller rezipientenstamm eines mycolsäure-haltigen bakteriums, verfahren zu dessen herstellung und dessen verwendung WO2002081676A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002316837A AU2002316837A1 (en) 2001-04-04 2002-04-04 Non-pathogenic bacterial recipient strain of a bacterium containing mycolic acid, method for the production thereof and use of the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10116788.1 2001-04-04
DE2001116788 DE10116788A1 (de) 2001-04-04 2001-04-04 Nichtpathogener bakterieller Poringen-Rezipientenstamm eines Mycolsäure-haltigen Bakteriums, Verfahren zu dessen Herstellung und dessen Verwendung

Publications (2)

Publication Number Publication Date
WO2002081676A2 WO2002081676A2 (de) 2002-10-17
WO2002081676A3 true WO2002081676A3 (de) 2004-04-01

Family

ID=7680364

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/003733 WO2002081676A2 (de) 2001-04-04 2002-04-04 Nichtpathogener bakterieller rezipientenstamm eines mycolsäure-haltigen bakteriums, verfahren zu dessen herstellung und dessen verwendung

Country Status (3)

Country Link
AU (1) AU2002316837A1 (de)
DE (1) DE10116788A1 (de)
WO (1) WO2002081676A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3029467B1 (de) * 2008-09-22 2020-01-08 University of Washington Msp-nanoporen und entsprechende verfahren

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
KAPS I ET AL: "Energy transfer between fluorescent proteins using a co-expression system in Mycobacterium smegmatis", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 278, no. 1-2, 31 October 2001 (2001-10-31), pages 115 - 124, XP004322247 *
MCFADDEN J: "RECOMBINATION IN MYCOBACTERIA", MOLECULAR MICROBIOLOGY, BLACKWELL SCIENTIFIC, OXFORD, GB, vol. 21, no. 2, 1996, pages 205 - 211, XP001070919 *
PELICIC V ET AL: "EFFICIENT ALLELIC EXCHANGE AND TRANSPOSON MUTAGENESIS IN MYCOBACTERIUM TUBERCULOSIS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 94, no. 20, 1 September 1997 (1997-09-01), pages 10955 - 10960, XP002054882 *
STAHL CLAUDIA ET AL: "MspA provides the main hydrophilic pathway through the cell wall of Mycobacterium smegmatis.", MOLECULAR MICROBIOLOGY, vol. 40, no. 2, April 2001 (2001-04-01), pages 451 - 464, XP002220575 *

Also Published As

Publication number Publication date
DE10116788A1 (de) 2002-10-17
AU2002316837A1 (en) 2002-10-21
WO2002081676A2 (de) 2002-10-17

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