WO2002076970A3 - Tocopherol succinate derivatives and compositions - Google Patents

Tocopherol succinate derivatives and compositions Download PDF

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Publication number
WO2002076970A3
WO2002076970A3 PCT/US2002/011264 US0211264W WO02076970A3 WO 2002076970 A3 WO2002076970 A3 WO 2002076970A3 US 0211264 W US0211264 W US 0211264W WO 02076970 A3 WO02076970 A3 WO 02076970A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
tocopherol succinate
succinate derivatives
succinic acid
tocopherol
Prior art date
Application number
PCT/US2002/011264
Other languages
French (fr)
Other versions
WO2002076970A2 (en
Inventor
Karel J Lambert
Manjari Lal
Andrew M Nienstedt
Original Assignee
Sonus Pharma Inc
Karel J Lambert
Manjari Lal
Andrew M Nienstedt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonus Pharma Inc, Karel J Lambert, Manjari Lal, Andrew M Nienstedt filed Critical Sonus Pharma Inc
Publication of WO2002076970A2 publication Critical patent/WO2002076970A2/en
Publication of WO2002076970A3 publication Critical patent/WO2002076970A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

Tocopherol succinic acid derivatives including tocopherol succinic acid esters and tocopherol succinic acid amides are described. Compositions that include the tocopherol succinic acid derivatives are also provided.
PCT/US2002/011264 2001-03-23 2002-03-21 Tocopherol succinate derivatives and compositions WO2002076970A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27826401P 2001-03-23 2001-03-23
US60/278,264 2001-03-23

Publications (2)

Publication Number Publication Date
WO2002076970A2 WO2002076970A2 (en) 2002-10-03
WO2002076970A3 true WO2002076970A3 (en) 2002-11-14

Family

ID=23064325

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/011264 WO2002076970A2 (en) 2001-03-23 2002-03-21 Tocopherol succinate derivatives and compositions

Country Status (1)

Country Link
WO (1) WO2002076970A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9320295B2 (en) 2010-03-23 2016-04-26 Virun, Inc. Compositions containing non-polar compounds
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219274A1 (en) * 2003-04-29 2004-11-04 Cook Phillip Michael Beverages containing water-soluble vitamin E
DE602004027936D1 (en) * 2003-10-29 2010-08-12 Sonus Pharmaceutical Inc TOCOPHEROL-MODIFIED THERAPEUTIC DRUG COMPOUND
CA2574767C (en) 2004-07-19 2015-02-17 Celator Pharmaceuticals, Inc. Particulate constructs for release of active agents
EP2268274B1 (en) 2008-03-20 2012-05-16 Virun, Inc. Vitamin e derivatives and their uses
CN107080734B (en) * 2008-03-20 2020-10-30 维尔恩公司 Emulsions comprising PEG derivatives of tocopherols
US8741373B2 (en) 2010-06-21 2014-06-03 Virun, Inc. Compositions containing non-polar compounds
EP2771341A4 (en) * 2011-10-28 2015-09-23 Univ Texas Novel compositions and methods for treating cancer
CN102491981B (en) * 2011-11-11 2014-11-19 南京美西宁医药科技有限责任公司 Amphiphilic anti-cancer drug compound modified by water-soluble vitamin E derivative, preparation, preparation method and application for compound
WO2013120025A1 (en) 2012-02-10 2013-08-15 Virun, Inc. Beverage compositions containing non-polar compounds
US9693574B2 (en) 2013-08-08 2017-07-04 Virun, Inc. Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch
US10016363B2 (en) 2014-09-18 2018-07-10 Virun, Inc. Pre-spray emulsions and powders containing non-polar compounds
US9861611B2 (en) 2014-09-18 2018-01-09 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same
CN106137963B (en) * 2016-07-27 2019-07-30 武汉科福新药有限责任公司 Antiarrhythmic drug fat emulsion injection and preparation method thereof
US11980636B2 (en) 2020-11-18 2024-05-14 Jazz Pharmaceuticals Ireland Limited Treatment of hematological disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234695A (en) * 1990-07-24 1993-08-10 Eastman Kodak Company Water dispersible vitamin E composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234695A (en) * 1990-07-24 1993-08-10 Eastman Kodak Company Water dispersible vitamin E composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9320295B2 (en) 2010-03-23 2016-04-26 Virun, Inc. Compositions containing non-polar compounds
US9351517B2 (en) 2013-03-15 2016-05-31 Virun, Inc. Formulations of water-soluble derivatives of vitamin E and compositions containing same

Also Published As

Publication number Publication date
WO2002076970A2 (en) 2002-10-03

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