WO2002074354B1 - Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials - Google Patents

Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials

Info

Publication number
WO2002074354B1
WO2002074354B1 PCT/FI2002/000209 FI0200209W WO02074354B1 WO 2002074354 B1 WO2002074354 B1 WO 2002074354B1 FI 0200209 W FI0200209 W FI 0200209W WO 02074354 B1 WO02074354 B1 WO 02074354B1
Authority
WO
WIPO (PCT)
Prior art keywords
gels
sols
mixtures
composites
sol
Prior art date
Application number
PCT/FI2002/000209
Other languages
French (fr)
Other versions
WO2002074354A1 (en
WO2002074354A8 (en
Inventor
Niko Moritz
Ilkka Kangasniemi
Antti Yli-Urpo
Timo Peltola
Mika Jokinen
Original Assignee
Bioxid Oy
Niko Moritz
Ilkka Kangasniemi
Antti Yli-Urpo
Timo Peltola
Mika Jokinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20010523A external-priority patent/FI20010523A0/en
Application filed by Bioxid Oy, Niko Moritz, Ilkka Kangasniemi, Antti Yli-Urpo, Timo Peltola, Mika Jokinen filed Critical Bioxid Oy
Priority to AU2002240976A priority Critical patent/AU2002240976A1/en
Priority to EP02706800A priority patent/EP1368071A1/en
Priority to US10/472,113 priority patent/US20040121451A1/en
Publication of WO2002074354A1 publication Critical patent/WO2002074354A1/en
Publication of WO2002074354A8 publication Critical patent/WO2002074354A8/en
Publication of WO2002074354B1 publication Critical patent/WO2002074354B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B19/00—Other methods of shaping glass
    • C03B19/12—Other methods of shaping glass by liquid-phase reaction processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/10—Ceramics or glasses
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B23/00—Re-forming shaped glass
    • C03B23/20—Uniting glass pieces by fusing without substantial reshaping
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B32/00—Thermal after-treatment of glass products not provided for in groups C03B19/00, C03B25/00 - C03B31/00 or C03B37/00, e.g. crystallisation, eliminating gas inclusions or other impurities; Hot-pressing vitrified, non-porous, shaped glass products
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C1/00—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels
    • C03C1/006—Ingredients generally applicable to manufacture of glasses, glazes, or vitreous enamels to produce glass through wet route
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C26/00—Coating not provided for in groups C23C2/00 - C23C24/00
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C26/00—Coating not provided for in groups C23C2/00 - C23C24/00
    • C23C26/02—Coating not provided for in groups C23C2/00 - C23C24/00 applying molten material to the substrate
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23D—ENAMELLING OF, OR APPLYING A VITREOUS LAYER TO, METALS
    • C23D15/00—Joining enamelled articles to other enamelled articles by processes involving an enamelling step
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23D—ENAMELLING OF, OR APPLYING A VITREOUS LAYER TO, METALS
    • C23D5/00—Coating with enamels or vitreous layers
    • C23D5/04—Coating with enamels or vitreous layers by dry methods
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B2201/00—Type of glass produced
    • C03B2201/06—Doped silica-based glasses
    • C03B2201/30—Doped silica-based glasses doped with metals, e.g. Ga, Sn, Sb, Pb or Bi
    • C03B2201/40—Doped silica-based glasses doped with metals, e.g. Ga, Sn, Sb, Pb or Bi doped with transition metals other than rare earth metals, e.g. Zr, Nb, Ta or Zn
    • C03B2201/42—Doped silica-based glasses doped with metals, e.g. Ga, Sn, Sb, Pb or Bi doped with transition metals other than rare earth metals, e.g. Zr, Nb, Ta or Zn doped with titanium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Inorganic Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Ceramic Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

An object of the invention is a method for at least partially treating biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, said sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials comprising OH-groups and being at least partially amorphous, the said treatment being performed with a localised electromagnetic and/or acoustic energy. Other objects of the invention are a method for coating a device with biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials and a method for modifying the biological activity of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials. All these methods use treatment with localised electromagnetic and/or acoustic energy. The invention also relates to the use of said method for the fabrication of different devices and to the attachment of at least two devices.

Claims

27 AMENDED CLAIMS[Received by the International Bureau on 13 September 2002 (13.09.02): original claims 1-23 replaced by amended claims claims 1-23 ( 3 pages)]
1. Method for at least partially treating biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, said sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials comprising OH-groups, being at least partially amorphous and selected from the group consisting of silica, titania, alumina, calcium phosphates, zirconia based and mixtures thereof, the said treatment being performed with a localised electromagnetic and/or acoustic energy.
2. Method according to claim 1, characterised in that said treatment consists of consolidation, densification, polycondensation and/or sintering.
3. Method according to claim 1 or 2, characterised in that the localised electromagnetic and/or acoustic energy is selected from the group consisting of laser irradiation, infrared irradiation, ultraviolet irradiation, visible light, X-ray irradiation, microwave irradiation and ultrasound waves.
4. Method according to any of claims 1-3, characterised in that the layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials comprises or acts as a biologically active agent.
5. A method for coating a device with biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, characterised in that at least one layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, selected from the group consisting of silica, titania, alumina, calcium phosphates, zirconia based and mixtures thereof, is deposited on the surface of the device and that each said layer is treated with a localised electromagnetic and/or acoustic energy prior to the eventual deposition of , another layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials.
6. Method according to claim 5, characterised in that the device is manufactured from a biocompatible material.
7. Method according to claim 5 or 6, characterised in that the thickness of each layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials deposited on the surface of the device is from 10 nm to 1000 nm, preferably from 10 nm to 200 nm, more preferably from 40 nm to 80 nm.
8. Method according to any of claims 5-7, characterised in that each layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials is deposited on the surface of the device by dipping, spinning, spraying or chemical treatment.
9. Method according to any of claims 5-8, characterised in that the layer of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials deposited on the surface of the device comprises or acts as a biologically active agent.
10. Method according to any of claims 5-9, characterised in that the device is a delivery device or a bioactive device.
11. Method according to any of claims 5-10, characterised in that the localised electromagnetic and/or acoustic energy is selected from the group consisting of laser irradiation, infrared irradiation, ultraviolet irradiation, visible light, X-ray irradiation, microwave irradiation and ultrasound waves.
12. A method for modifying the biological activity of biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, characterised in that at least portion of the surface of the biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials, selected from the group consisting of silica, titania, alumina, calcium phosphates, zirconia based and mixtures thereof, is treated with a localised electromagnetic and/or acoustic energy.
13. Use of the method according to claim 1 for the manufacture of devices consisting essentially of biologically active sols, gels, mixtures or composites of sols and gels, mixtures or composites of sols and gels, and/or sol-gel derived materials.
14. A fibre, characterised in that it has been prepared according to the method of claim 1.
15. A monolith, characterised in that it has been prepared according to the method of claim 1.
16. A granulate, characterised in that it has been prepared according to the method of claim 1. 29
17. A woven or nonwoven mat, characterised in that it has been prepared according to the method of claim 1.
18. A tissue-guiding device, characterised in that it has been prepared according to the method of claim 1.
19. A film, characterised in that it has been prepared according to the method of claim 1.
20. A coating, characterised in that it has been prepared according to the method of claim 1.
21. A method for attaching at least two devices, characterised in that the joint between said at least two devices is formed by at least partially treating said biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials present in the location of the joint according to the method of any of claims 1-4.
22. Method according to claim 21, characterised in that at least one of the devices has been coated according to any of claims 5-11.
23. Method according to claim 21 or 22, characterised in that at least one of the devices has been manufactured from biologically active sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials.
PCT/FI2002/000209 2001-03-16 2002-03-15 Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials WO2002074354A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002240976A AU2002240976A1 (en) 2001-03-16 2002-03-15 Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials
EP02706800A EP1368071A1 (en) 2001-03-16 2002-03-15 Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials
US10/472,113 US20040121451A1 (en) 2001-03-16 2002-03-15 Treatment of sols, gels and mixtures thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27621401P 2001-03-16 2001-03-16
FI20010523 2001-03-16
FI20010523A FI20010523A0 (en) 2001-03-16 2001-03-16 Treatment of sols, gels and mixtures thereof
US60/276,214 2001-03-16

Publications (3)

Publication Number Publication Date
WO2002074354A1 WO2002074354A1 (en) 2002-09-26
WO2002074354A8 WO2002074354A8 (en) 2002-10-24
WO2002074354B1 true WO2002074354B1 (en) 2002-11-21

Family

ID=26161145

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2002/000209 WO2002074354A1 (en) 2001-03-16 2002-03-15 Treatment of sols, gels, mixtures or composites of sols and gels, and/or sol-gel derived materials

Country Status (3)

Country Link
EP (1) EP1368071A1 (en)
AU (1) AU2002240976A1 (en)
WO (1) WO2002074354A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1611906A1 (en) * 2004-06-30 2006-01-04 YLI-URPO, Antti A multilayer material

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4897433A (en) * 1986-12-08 1990-01-30 Japan Atomic Energy Research Inst. Process for producing an anti-thrombogenic material by graft polymerization
EP0363504A1 (en) * 1988-10-10 1990-04-18 Dräger Nederland B.V. Method of providing a substrate with a layer comprising a polyvinylbased hydrogel and a biochemically active material
JP2930329B2 (en) * 1989-09-28 1999-08-03 ソニー株式会社 Antithrombotic material
US5171264A (en) * 1990-02-28 1992-12-15 Massachusetts Institute Of Technology Immobilized polyethylene oxide star molecules for bioapplications
US5529914A (en) * 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
JP3093375B2 (en) * 1991-11-01 2000-10-03 株式会社東海メディカルプロダクツ Immobilization method of antithrombotic substance
BR9306038A (en) * 1992-02-28 1998-01-13 Univ Texas Light-curing biodegradable hydrogels as contact materials for controlled release fabrics and conductors

Also Published As

Publication number Publication date
WO2002074354A1 (en) 2002-09-26
WO2002074354A8 (en) 2002-10-24
EP1368071A1 (en) 2003-12-10
AU2002240976A1 (en) 2002-10-03

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