WO2002072794A3 - Proteines de la superfamille des immunoglobulines - Google Patents

Proteines de la superfamille des immunoglobulines Download PDF

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Publication number
WO2002072794A3
WO2002072794A3 PCT/US2002/009052 US0209052W WO02072794A3 WO 2002072794 A3 WO2002072794 A3 WO 2002072794A3 US 0209052 W US0209052 W US 0209052W WO 02072794 A3 WO02072794 A3 WO 02072794A3
Authority
WO
WIPO (PCT)
Prior art keywords
immunoglobulin superfamily
igsfp
superfamily proteins
provides
proteins
Prior art date
Application number
PCT/US2002/009052
Other languages
English (en)
Other versions
WO2002072794A2 (fr
Inventor
Henry Yue
Yuming Xu
Kavitha Thangavelu
Bridget A Warren
Y Tom Tang
Brendan M Duggan
Uyen K Tran
Mariah R Baughn
Cynthia D Honchell
Neil Burford
Ian J Forsythe
Junming Yang
Patricia M Mason
Original Assignee
Incyte Genomics Inc
Henry Yue
Yuming Xu
Kavitha Thangavelu
Bridget A Warren
Y Tom Tang
Brendan M Duggan
Uyen K Tran
Mariah R Baughn
Cynthia D Honchell
Neil Burford
Ian J Forsythe
Junming Yang
Patricia M Mason
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Yuming Xu, Kavitha Thangavelu, Bridget A Warren, Y Tom Tang, Brendan M Duggan, Uyen K Tran, Mariah R Baughn, Cynthia D Honchell, Neil Burford, Ian J Forsythe, Junming Yang, Patricia M Mason filed Critical Incyte Genomics Inc
Priority to US10/471,449 priority Critical patent/US20040097711A1/en
Priority to EP02726671A priority patent/EP1409655A4/fr
Priority to AU2002257088A priority patent/AU2002257088A1/en
Priority to CA002440618A priority patent/CA2440618A1/fr
Priority to JP2002571850A priority patent/JP2004533222A/ja
Publication of WO2002072794A2 publication Critical patent/WO2002072794A2/fr
Publication of WO2002072794A3 publication Critical patent/WO2002072794A3/fr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

L'invention concerne des protéines de la superfamille des immunoglobulines humaines (IGSFP) et des polynucléotides identifiant et codant les IGSFP. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes ainsi que des antagonistes. L'invention concerne également des méthodes de diagnostic, de traitement ou de prévention de troubles associés à l'expression aberrante d'IGSFP.
PCT/US2002/009052 2001-03-12 2002-03-12 Proteines de la superfamille des immunoglobulines WO2002072794A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/471,449 US20040097711A1 (en) 2002-03-12 2002-03-12 Immunoglobulin superfamily proteins
EP02726671A EP1409655A4 (fr) 2001-03-12 2002-03-12 Proteines de la superfamille des immunoglobulines
AU2002257088A AU2002257088A1 (en) 2001-03-12 2002-03-12 Immunoglobulin superfamily proteins
CA002440618A CA2440618A1 (fr) 2001-03-12 2002-03-12 Proteines de la superfamille des immunoglobulines
JP2002571850A JP2004533222A (ja) 2001-03-12 2002-03-12 免疫グロブリンスーパーファミリータンパク質

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US27524901P 2001-03-12 2001-03-12
US60/275,249 2001-03-12
US31681001P 2001-08-31 2001-08-31
US60/316,810 2001-08-31
US32397701P 2001-09-21 2001-09-21
US60/323,977 2001-09-21
US34844701P 2001-10-26 2001-10-26
US60/348,447 2001-10-26
US34388001P 2001-11-02 2001-11-02
US60/343,880 2001-11-02

Publications (2)

Publication Number Publication Date
WO2002072794A2 WO2002072794A2 (fr) 2002-09-19
WO2002072794A3 true WO2002072794A3 (fr) 2004-01-29

Family

ID=27540591

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009052 WO2002072794A2 (fr) 2001-03-12 2002-03-12 Proteines de la superfamille des immunoglobulines

Country Status (5)

Country Link
EP (1) EP1409655A4 (fr)
JP (1) JP2004533222A (fr)
AU (1) AU2002257088A1 (fr)
CA (1) CA2440618A1 (fr)
WO (1) WO2002072794A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074906A2 (fr) * 2001-03-16 2002-09-26 Eli Lilly And Company Proteines de mammiferes lp et reactifs associes
MXPA04001986A (es) * 2001-08-29 2004-06-07 Genentech Inc Composiciones y metodos para el tratamiento de enfermedades relacionadas a la inmunidad.
CA2489803A1 (fr) 2002-06-20 2003-12-31 The Regents Of The University Of California Compositions et procedes de modulation de l'activite lymphocytaire
US8546541B2 (en) 2002-06-20 2013-10-01 Washington University Compositions and methods for modulating lymphocyte activity
CA2503125C (fr) 2002-10-25 2013-04-30 Hilary Clark Nouvelle composition et procedes pour le traitement de maladies auto-immunes
US20040109863A1 (en) * 2002-12-04 2004-06-10 Peter Emtage Methods of therapy and diagnosis using targeting of cells that express Ly-9
US20040248257A1 (en) * 2003-04-30 2004-12-09 The Scripps Research Institute SPEX compositions and methods of use
EP1812465B1 (fr) * 2004-11-12 2016-09-07 Genentech, Inc. Nouvelle composition et methodes permettant de traiter les maladies liees au systeme immunitaire
US8188232B1 (en) 2004-11-15 2012-05-29 Washington University In St. Louis Compositions and methods for modulating lymphocyte activity
US8303952B2 (en) 2009-06-08 2012-11-06 Washington University Methods for inducing in vivo tolerance
CN105188749B (zh) 2012-12-21 2017-12-19 西雅图基因公司 抗ntb‑a抗体及相关组合物和方法
MX2016003525A (es) 2013-09-17 2017-01-06 Univ Health Network (Uhn) Agentes dirigidos contra una interaccion cis de molecula de orientacion repulsiva a (rgma) /neogenina o balsas lipidicas y uso de los mismos en metodos de tratamiento.
EP2905622A1 (fr) * 2014-02-07 2015-08-12 Institut D'Investigaciones Biomédiques August Pi i Sunyer Diagnostic d'une maladie neurologique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000029583A2 (fr) * 1998-11-19 2000-05-25 Incyte Pharmaceuticals, Inc. Proteines de la superfamille des immunoglobulines
JP2002538841A (ja) * 1999-03-18 2002-11-19 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 27個のヒト分泌タンパク質
CA2391455A1 (fr) * 1999-12-01 2001-06-07 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2004501623A (ja) * 2000-06-27 2004-01-22 キュラジェン コーポレイション ポリヌクレオチドおよびそれによってコードされるポリペプチド
JP2005500815A (ja) * 2000-12-29 2005-01-13 キュラジェン コーポレイション タンパク質およびそれをコードする核酸
EP1402058A4 (fr) * 2001-06-05 2006-02-01 Exelixis Inc Dgk en tant que modulateurs du mecanisme d'action de p53 et procedes d'utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] June 2001 (2001-06-01), NAGASE ET AL., XP002970308, accession no. NCBI Database accession no. (BAB47496) *
See also references of EP1409655A4 *

Also Published As

Publication number Publication date
EP1409655A4 (fr) 2005-04-06
EP1409655A2 (fr) 2004-04-21
JP2004533222A (ja) 2004-11-04
CA2440618A1 (fr) 2002-09-19
WO2002072794A2 (fr) 2002-09-19
AU2002257088A1 (en) 2002-09-24

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