WO2002072619A8 - INTEGRIN αIIbβ3 ACTIVATING PEPTIDES AND THEIR USE - Google Patents

INTEGRIN αIIbβ3 ACTIVATING PEPTIDES AND THEIR USE

Info

Publication number
WO2002072619A8
WO2002072619A8 PCT/FI2002/000193 FI0200193W WO02072619A8 WO 2002072619 A8 WO2002072619 A8 WO 2002072619A8 FI 0200193 W FI0200193 W FI 0200193W WO 02072619 A8 WO02072619 A8 WO 02072619A8
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
activating peptides
integrin αiibβ3
novel peptides
pharmaceutical compositions
Prior art date
Application number
PCT/FI2002/000193
Other languages
French (fr)
Other versions
WO2002072619A9 (en
WO2002072619A1 (en
Inventor
Erkki Koivunen
Carl G Gahmberg
Original Assignee
Ctt Cancer Targeting Tech Oy
Erkki Koivunen
Carl G Gahmberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ctt Cancer Targeting Tech Oy, Erkki Koivunen, Carl G Gahmberg filed Critical Ctt Cancer Targeting Tech Oy
Priority to EP02706792A priority Critical patent/EP1373304A1/en
Priority to AU2002240968A priority patent/AU2002240968A1/en
Publication of WO2002072619A1 publication Critical patent/WO2002072619A1/en
Publication of WO2002072619A8 publication Critical patent/WO2002072619A8/en
Publication of WO2002072619A9 publication Critical patent/WO2002072619A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to novel peptides which are useful as αIIbβ3 integrin activators, to pharmaceutical compositions comprising these peptides, to the use of the novel peptides for the manufacture of pharmaceutical compositions for the treatment of thrombotic diseases and bleeding disorders, to a method for therapeutic or prophylactic treatment of thrombotic diseases and bleeding disorders and to the use of the novel peptides in artificial tissue transplants to aid in wound healing and tissue regeneration.
PCT/FI2002/000193 2001-03-12 2002-03-12 INTEGRIN αIIbβ3 ACTIVATING PEPTIDES AND THEIR USE WO2002072619A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02706792A EP1373304A1 (en) 2001-03-12 2002-03-12 INTEGRIN ALPHA IIbBETA 3 ACTIVIVING PEPTIDES AND THEIR USE
AU2002240968A AU2002240968A1 (en) 2001-03-12 2002-03-12 Integrin alphaiibbeta3 activating peptides and their use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20010492A FI20010492A0 (en) 2001-03-12 2001-03-12 Identification of a new functional binding site for the platelet integrin alpha IIbbeta 3 in the von Willebrand factor A3 domain
FI20010492 2001-03-12

Publications (3)

Publication Number Publication Date
WO2002072619A1 WO2002072619A1 (en) 2002-09-19
WO2002072619A8 true WO2002072619A8 (en) 2002-10-17
WO2002072619A9 WO2002072619A9 (en) 2002-12-27

Family

ID=8560722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2002/000193 WO2002072619A1 (en) 2001-03-12 2002-03-12 INTEGRIN αIIbβ3 ACTIVATING PEPTIDES AND THEIR USE

Country Status (4)

Country Link
EP (1) EP1373304A1 (en)
AU (1) AU2002240968A1 (en)
FI (1) FI20010492A0 (en)
WO (1) WO2002072619A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1757592A (en) * 1991-03-27 1992-11-02 Scripps Research Institute, The Therapeutic fragments of von willebrand factor
CA2293693A1 (en) * 1997-06-06 1998-12-10 Asat Ag Applied Science & Technology Anti-gpiib/iiia recombinant antibodies
WO1999021879A1 (en) * 1997-10-27 1999-05-06 Intrabiotics Pharmaceuticals, Inc. Cyclic peptides having broad spectrum antimicrobial activity

Also Published As

Publication number Publication date
WO2002072619A9 (en) 2002-12-27
FI20010492A0 (en) 2001-03-12
EP1373304A1 (en) 2004-01-02
WO2002072619A1 (en) 2002-09-19
AU2002240968A1 (en) 2002-09-24

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