WO2002068647A3 - Proteins, polynucleotides encoding them and methods of using the same - Google Patents

Proteins, polynucleotides encoding them and methods of using the same Download PDF

Info

Publication number
WO2002068647A3
WO2002068647A3 PCT/US2002/001311 US0201311W WO02068647A3 WO 2002068647 A3 WO2002068647 A3 WO 2002068647A3 US 0201311 W US0201311 W US 0201311W WO 02068647 A3 WO02068647 A3 WO 02068647A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
methods
same
polynucleotides encoding
disclosed
Prior art date
Application number
PCT/US2002/001311
Other languages
French (fr)
Other versions
WO2002068647A2 (en
Inventor
Muralidhara Padigaru
John P Ii Alsobrook
Steven D Colman
Kimberly A Spytek
Ferenc Boldog
Corine A M Vernet
Li Li
Suresh Shenoy
Stacie Casman
Xiaojia Guo
Original Assignee
Curagen Corp
Muralidhara Padigaru
John P Ii Alsobrook
Steven D Colman
Kimberly A Spytek
Ferenc Boldog
Corine A M Vernet
Li Li
Suresh Shenoy
Stacie Casman
Xiaojia Guo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Muralidhara Padigaru, John P Ii Alsobrook, Steven D Colman, Kimberly A Spytek, Ferenc Boldog, Corine A M Vernet, Li Li, Suresh Shenoy, Stacie Casman, Xiaojia Guo filed Critical Curagen Corp
Priority to JP2002568741A priority Critical patent/JP2005501516A/en
Priority to CA002434690A priority patent/CA2434690A1/en
Priority to EP02761846A priority patent/EP1370659A2/en
Publication of WO2002068647A2 publication Critical patent/WO2002068647A2/en
Publication of WO2002068647A3 publication Critical patent/WO2002068647A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.
PCT/US2002/001311 2001-01-16 2002-01-16 Proteins, polynucleotides encoding them and methods of using the same WO2002068647A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2002568741A JP2005501516A (en) 2001-01-16 2002-01-16 Protein, polynucleotide encoding the protein, and methods of use thereof
CA002434690A CA2434690A1 (en) 2001-01-16 2002-01-16 Proteins, polynucleotides encoding them and methods of using the same
EP02761846A EP1370659A2 (en) 2001-01-16 2002-01-16 Proteins, polynucleotides encoding them and methods of using the same

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US26137601P 2001-01-16 2001-01-16
US60/261,376 2001-01-16
US26245401P 2001-01-18 2001-01-18
US26258701P 2001-01-18 2001-01-18
US60/262,454 2001-01-18
US60/262,587 2001-01-18
US26553001P 2001-01-31 2001-01-31
US60/265,530 2001-01-31
US26859501P 2001-02-14 2001-02-14
US60/268,595 2001-02-14
US27240901P 2001-02-28 2001-02-28
US60/272,409 2001-02-28
US27677701P 2001-03-16 2001-03-16
US60/276,777 2001-03-16
US29167201P 2001-05-17 2001-05-17
US60/291,672 2001-05-17
US32530601P 2001-09-27 2001-09-27
US32550601P 2001-09-27 2001-09-27
US60/325,306 2001-09-27
US33033601P 2001-10-18 2001-10-18
US60/330,336 2001-10-18
US34520201P 2001-11-09 2001-11-09
US60/345,202 2001-11-09

Publications (2)

Publication Number Publication Date
WO2002068647A2 WO2002068647A2 (en) 2002-09-06
WO2002068647A3 true WO2002068647A3 (en) 2003-09-25

Family

ID=28047102

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/001311 WO2002068647A2 (en) 2001-01-16 2002-01-16 Proteins, polynucleotides encoding them and methods of using the same

Country Status (1)

Country Link
WO (1) WO2002068647A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2275547B1 (en) 2004-12-13 2014-03-05 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
MX349137B (en) 2005-06-08 2017-07-13 Dana-Farber Cancer Inst Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway.
BRPI0921321A2 (en) 2008-11-28 2018-10-16 Emory University methods for the treatment of tumors and tumors
CN108997498A (en) 2008-12-09 2018-12-14 霍夫曼-拉罗奇有限公司 Anti- PD-L1 antibody and they be used to enhance the purposes of T cell function
EP3094736A4 (en) 2014-01-14 2017-10-25 Dana-Farber Cancer Institute, Inc. Compositions and methods for identification, assessment, prevention, and treatment of melanoma using pd-l1 isoforms

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009800A1 (en) * 1991-11-14 1993-05-27 La Jolla Cancer Research Foundation Inhibitors of cell regulatory factors and methods for preventing or reducing scarring
WO2000055350A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human cancer associated gene sequences and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009800A1 (en) * 1991-11-14 1993-05-27 La Jolla Cancer Research Foundation Inhibitors of cell regulatory factors and methods for preventing or reducing scarring
WO2000055350A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human cancer associated gene sequences and polypeptides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ANTONSSON P ET AL: "STRUCTURE AND DEDUCED AMINO ACID SEQUENCE OF THE HUMAN FIBROMODULIN GENE", BIOCHIMICA ET BIOPHYSICA ACTA, AMSTERDAM, NL, vol. 1174, no. 2, 1993, pages 204 - 206, XP001112988, ISSN: 0006-3002 *
See also references of EP1370659A2 *

Also Published As

Publication number Publication date
WO2002068647A2 (en) 2002-09-06

Similar Documents

Publication Publication Date Title
WO2002014368A3 (en) Proteins and nucleic acids encoding the same
WO2002006339A3 (en) Proteins and nucleic acids encoding same
WO2002055705A3 (en) Proteins and nucleic acids encoding same
WO2002064791A3 (en) Proteins and nucleic acids encoding same
WO2002050277A3 (en) Protein and nucleic acids encoding same
WO2002057453A3 (en) Polypetides and nucleic acids encoding same
WO2002068649A3 (en) Proteins and nucleic acids encoding same
WO2002057450A3 (en) Proteins and nucleic acids encoding same
WO2002081518A3 (en) Proteins, polynucleotides encoding them and methods of using the same
WO2002029058A3 (en) Human proteins, polynucleotides encoding them and methods of using the same
WO2001090155A3 (en) Novx proteins and nucleic acids encoding same. diagnostic and therapeutic uses
WO2002098917A3 (en) Human proteins and nucleic acids encoding same
WO2001081578A3 (en) Novel proteins and nucleic acids encoding same
WO2004015060A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2002068652A3 (en) Nov-x proteins and nucleic acids encoding same
WO2002016599A3 (en) Proteins and nucleic acids encoding same
WO2002055704A3 (en) Proteins, polynucleotides encoding them and methods of using the same
WO2002029038A3 (en) Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
WO2002081510A3 (en) Proteins, polynucleotides encoding them and methods of using the same
WO2002055702A3 (en) Human proteins, polynucleotides encoding them and methods of using the same
WO2002010216A3 (en) Proteins and nucleic acids encoding same
WO2002066643A3 (en) Proteins, polynucleotides encoding them and methods of using the same
WO2002046229A3 (en) Novel proteins and nucleic acids encoding same
WO2001066747A8 (en) Proteins named fctrx and nucleic acids encoding same
WO2002099116A8 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use

Legal Events

Date Code Title Description
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2434690

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002568741

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002306414

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2002761846

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 2002761846

Country of ref document: EP

WWR Wipo information: refused in national office

Ref document number: 2002761846

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2002761846

Country of ref document: EP