WO2002068056A3 - Combination comprising a 1,4-dioxonaphathalene compound and ribenoside - Google Patents

Combination comprising a 1,4-dioxonaphathalene compound and ribenoside Download PDF

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Publication number
WO2002068056A3
WO2002068056A3 PCT/GB2002/000791 GB0200791W WO02068056A3 WO 2002068056 A3 WO2002068056 A3 WO 2002068056A3 GB 0200791 W GB0200791 W GB 0200791W WO 02068056 A3 WO02068056 A3 WO 02068056A3
Authority
WO
WIPO (PCT)
Prior art keywords
compound
combination
ribenoside
dioxonaphathalene
tribenoside
Prior art date
Application number
PCT/GB2002/000791
Other languages
French (fr)
Other versions
WO2002068056A2 (en
Inventor
Kim Sze Tan
Joseph Di Chayen
Original Assignee
Ks Biomedix Holdings Plc
Kim Sze Tan
Avron Ann Hf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ks Biomedix Holdings Plc, Kim Sze Tan, Avron Ann Hf filed Critical Ks Biomedix Holdings Plc
Priority to AU2002233539A priority Critical patent/AU2002233539A1/en
Publication of WO2002068056A2 publication Critical patent/WO2002068056A2/en
Publication of WO2002068056A3 publication Critical patent/WO2002068056A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to composition for use in the treatment of inflammatory conditions, such as Rheumatoid Arthritis, and Osteoarthritis (OA), as well as in the treatment of pain. The composition comprise a 1,4-dioxonapthalene compound or pharmaceutically acceptable salt thereof, in combination tribenoside or a tribenoside analogue. In particular the invention relates to a composition, and its uses, comprising tribenoside and menadione bisulphite.
PCT/GB2002/000791 2001-02-23 2002-02-22 Combination comprising a 1,4-dioxonaphathalene compound and ribenoside WO2002068056A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002233539A AU2002233539A1 (en) 2001-02-23 2002-02-22 Combination comprising a 1,4-dioxonaphathalene compound and ribenoside

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0104571.5A GB0104571D0 (en) 2001-02-23 2001-02-23 Composition
GB0104571.5 2001-02-23

Publications (2)

Publication Number Publication Date
WO2002068056A2 WO2002068056A2 (en) 2002-09-06
WO2002068056A3 true WO2002068056A3 (en) 2003-05-15

Family

ID=9909401

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/000791 WO2002068056A2 (en) 2001-02-23 2002-02-22 Combination comprising a 1,4-dioxonaphathalene compound and ribenoside

Country Status (3)

Country Link
AU (1) AU2002233539A1 (en)
GB (1) GB0104571D0 (en)
WO (1) WO2002068056A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03161448A (en) * 1989-11-20 1991-07-11 Asahi Chem Ind Co Ltd Composition containing oil and fat
WO1992013532A2 (en) * 1991-02-04 1992-08-20 Joseph Chayen Naphthoquinone derivatives for the treatment of chronic inflammation
WO1996018403A1 (en) * 1994-12-16 1996-06-20 Ks Biomedix Ltd. Combined use of diclofenac and tribenoside to treat osteoarthritis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03161448A (en) * 1989-11-20 1991-07-11 Asahi Chem Ind Co Ltd Composition containing oil and fat
WO1992013532A2 (en) * 1991-02-04 1992-08-20 Joseph Chayen Naphthoquinone derivatives for the treatment of chronic inflammation
WO1996018403A1 (en) * 1994-12-16 1996-06-20 Ks Biomedix Ltd. Combined use of diclofenac and tribenoside to treat osteoarthritis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 1992, SAIKAWA SATOSHI E.A.: "Pharmaceutical formulations of fat-soluble drugs", XP002226746, Database accession no. 116:28149 *

Also Published As

Publication number Publication date
AU2002233539A1 (en) 2002-09-12
WO2002068056A2 (en) 2002-09-06
GB0104571D0 (en) 2001-04-11

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