WO2002066501A3 - PROTEIN-PROTEIN INTERACTIONS IN $i(HELICOBACTER PYLORI) - Google Patents

PROTEIN-PROTEIN INTERACTIONS IN $i(HELICOBACTER PYLORI) Download PDF

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Publication number
WO2002066501A3
WO2002066501A3 PCT/EP2001/015428 EP0115428W WO02066501A3 WO 2002066501 A3 WO2002066501 A3 WO 2002066501A3 EP 0115428 W EP0115428 W EP 0115428W WO 02066501 A3 WO02066501 A3 WO 02066501A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
helicobacter pylori
interactions
polypeptides
protein interactions
Prior art date
Application number
PCT/EP2001/015428
Other languages
French (fr)
Other versions
WO2002066501A2 (en
Inventor
Pierre Legrain
Jean-Christophe Rain
Frederic Colland
Reuse Hilde De
Agnes Labigne
Original Assignee
Hybrigenics Sa
Pasteur Institut
Pierre Legrain
Jean-Christophe Rain
Frederic Colland
Reuse Hilde De
Agnes Labigne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybrigenics Sa, Pasteur Institut, Pierre Legrain, Jean-Christophe Rain, Frederic Colland, Reuse Hilde De, Agnes Labigne filed Critical Hybrigenics Sa
Publication of WO2002066501A2 publication Critical patent/WO2002066501A2/en
Publication of WO2002066501A3 publication Critical patent/WO2002066501A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to protein-protein interactions of Helicobacter pylori. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening drugs for agents which modulate the interaction of proteins and pharmaceutical compositions that are capable of modulating the protein-protein interactions.
PCT/EP2001/015428 2001-01-02 2001-12-28 PROTEIN-PROTEIN INTERACTIONS IN $i(HELICOBACTER PYLORI) WO2002066501A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25930201P 2001-01-02 2001-01-02
US60/259,302 2001-01-02

Publications (2)

Publication Number Publication Date
WO2002066501A2 WO2002066501A2 (en) 2002-08-29
WO2002066501A3 true WO2002066501A3 (en) 2003-11-20

Family

ID=22984381

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/015428 WO2002066501A2 (en) 2001-01-02 2001-12-28 PROTEIN-PROTEIN INTERACTIONS IN $i(HELICOBACTER PYLORI)

Country Status (1)

Country Link
WO (1) WO2002066501A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1622933A2 (en) * 2003-04-22 2006-02-08 Intercell AG H. pylori antigens
US8106172B2 (en) 2003-06-10 2012-01-31 Biomerieux, B.V. Nucleic acid sequences that can be used as primers and probes in the amplification and detection of SARS coronavirus
CN108495650A (en) 2015-12-14 2018-09-04 慕尼黑工业大学 Helicobacter pylori vaccine
CN109071605A (en) * 2016-04-06 2018-12-21 伊玛提克斯生物技术有限公司 New type of peptides and peptide combinations for AML and other cancer immunotherapies
EP3272354A1 (en) 2016-07-20 2018-01-24 Technische Universität München Agents and methods for the prevention or treatment of h. pylori infections

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042612A1 (en) * 1998-02-18 1999-08-26 Institut Pasteur A fast and exhaustive method for selecting a prey polypeptide interacting with a bait polypeptide of interest: application to the construction of maps of interactors polypeptides
WO2000066722A1 (en) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection of prokaryotic dna for two hybrid systems helicobacter pylori protein-protein interactions and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042612A1 (en) * 1998-02-18 1999-08-26 Institut Pasteur A fast and exhaustive method for selecting a prey polypeptide interacting with a bait polypeptide of interest: application to the construction of maps of interactors polypeptides
WO2000066722A1 (en) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection of prokaryotic dna for two hybrid systems helicobacter pylori protein-protein interactions and application thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHALKER ALISON F ET AL: "Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis.", JOURNAL OF BACTERIOLOGY, vol. 183, no. 4, 2001, pages 1259 - 1268, XP002245013, ISSN: 0021-9193 *
LEGRAIN P ET AL: "Genome-wide protein interaction maps using two-hybrid systems", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 480, no. 1, 25 August 2000 (2000-08-25), pages 32 - 36, XP004337490, ISSN: 0014-5793 *
TOMB J-F ET AL: "THE COMPLETE GENOME SEQUENCE OF THE GASTRIC PATHOGEN HELICOBACTER PYLORI", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 388, no. 6642, 7 August 1997 (1997-08-07), pages 539 - 547,TABEL, XP002062106, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
WO2002066501A2 (en) 2002-08-29

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