WO2002062482A3 - Fluid separation devices, systems and methods - Google Patents

Fluid separation devices, systems and methods Download PDF

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Publication number
WO2002062482A3
WO2002062482A3 PCT/US2001/046940 US0146940W WO02062482A3 WO 2002062482 A3 WO2002062482 A3 WO 2002062482A3 US 0146940 W US0146940 W US 0146940W WO 02062482 A3 WO02062482 A3 WO 02062482A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
separated
centrifugal
composite
components
Prior art date
Application number
PCT/US2001/046940
Other languages
French (fr)
Other versions
WO2002062482A9 (en
WO2002062482A2 (en
Inventor
Dennis J Hlavinka
Thomas J Felt
Original Assignee
Gambro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Inc filed Critical Gambro Inc
Priority to EP01270123A priority Critical patent/EP1363739B1/en
Priority to AT01270123T priority patent/ATE537906T1/en
Priority to AU2002253801A priority patent/AU2002253801A1/en
Publication of WO2002062482A2 publication Critical patent/WO2002062482A2/en
Publication of WO2002062482A9 publication Critical patent/WO2002062482A9/en
Publication of WO2002062482A3 publication Critical patent/WO2002062482A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0231—Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • B04B7/08—Rotary bowls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/08—Arrangement or disposition of transmission gearing ; Couplings; Brakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/14—Balancing rotary bowls ; Schrappers
    • B04B2009/143—Balancing rotary bowls ; Schrappers by weight compensation with liquids

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Centrifugal Separators (AREA)
  • External Artificial Organs (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

A centrifugal fluid separation system is disclosed for centrifugally separating a composite fluid into components thereof. This centrifugal separation system includes at least a centrifugal rotor (40) which has a composite fluid containment area (42), several fluid flow channels and at least two separated component collection areas defined therein. A composite fluid to be separated is delivered to the fluid containment area from which it travels through an inlet channel (46) to a substantially circumferential fluid separation channel (50) where under centrifugal forces the composite fluid is separated into components which each then travel to distinct first and second separated fluid outlet channels (53, 54), and thence on to exit therefrom into the respective collection areas. The first and second fluid outlet channels also have respective first and second heights which are related to each other so as to provide a balanced fluid pressure relationship for the respective separated component fluids flowing therethrough. Such a pressure balance controls the interface of the separated fluid components within the circumferential separation channel.
PCT/US2001/046940 2000-11-02 2001-11-02 Fluid separation devices, systems and methods WO2002062482A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01270123A EP1363739B1 (en) 2000-11-02 2001-11-02 Fluid separation devices, systems and methods
AT01270123T ATE537906T1 (en) 2000-11-02 2001-11-02 DEVICES, SYSTEMS AND METHODS FOR FLUID SEPARATION
AU2002253801A AU2002253801A1 (en) 2000-11-02 2001-11-02 Fluid separation devices, systems and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24528200P 2000-11-02 2000-11-02
US60/245,282 2000-11-02

Publications (3)

Publication Number Publication Date
WO2002062482A2 WO2002062482A2 (en) 2002-08-15
WO2002062482A9 WO2002062482A9 (en) 2003-02-20
WO2002062482A3 true WO2002062482A3 (en) 2003-08-28

Family

ID=22926042

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2001/046953 WO2002036266A2 (en) 2000-11-02 2001-11-02 Fluid separation devices, systems and methods
PCT/US2001/046940 WO2002062482A2 (en) 2000-11-02 2001-11-02 Fluid separation devices, systems and methods

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046953 WO2002036266A2 (en) 2000-11-02 2001-11-02 Fluid separation devices, systems and methods

Country Status (5)

Country Link
US (4) US6773389B2 (en)
EP (2) EP1363739B1 (en)
AT (2) ATE537906T1 (en)
AU (2) AU2002253801A1 (en)
WO (2) WO2002036266A2 (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
EP1363739B1 (en) * 2000-11-02 2011-12-21 CaridianBCT, Inc. Fluid separation devices, systems and methods
US6807493B2 (en) * 2001-05-24 2004-10-19 International Business Machines Corporation Estimating flow rates in open-channel geometries having capillary pumping vanes
US6878105B2 (en) * 2001-08-16 2005-04-12 Baxter International Inc. Red blood cell processing systems and methods with deliberate under spill of red blood cells
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7211037B2 (en) 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
US7297272B2 (en) * 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
FR2850581B1 (en) * 2003-02-03 2005-09-09 Maco Pharma Sa PRECAUTIONED LOOP PICKUP SYSTEM
US7083323B2 (en) * 2003-05-19 2006-08-01 Advanced Technology Materials, Inc. Flexible mixing bag for mixing solids, liquids and gases
FR2878145B1 (en) * 2004-11-24 2007-01-05 Maco Pharma Sa POCKET SYSTEM FOR AUTOMATIC SAMPLING OF A BIOLOGICAL FLUID
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
WO2007001754A1 (en) * 2005-06-22 2007-01-04 Gambro Bct, Inc. Apparatus and method for separating discrete volumes of a composite liquid
WO2007024518A2 (en) * 2005-08-22 2007-03-01 Gambro Inc. Apparatus and method for separating a composite liquid into at least two components
EP1795894A1 (en) * 2005-12-06 2007-06-13 Roche Diagnostics GmbH Plasma separation on a disk like device
EP1981564B1 (en) * 2006-01-30 2009-11-25 CaridianBCT, Inc. Adjusting ph in a method of separating whole blood
KR100767448B1 (en) * 2006-06-30 2007-10-17 메디칸(주) Centrifuge and centrifuging method
US7555933B2 (en) * 2006-08-01 2009-07-07 Thermo Fisher Scientific Inc. Method and software for detecting vacuum concentrator ends-of-runs
AU2007292504A1 (en) * 2006-09-06 2008-03-13 Caridianbct, Inc. Apparatus and method for separating a composite liquid into at least two components
US20080147240A1 (en) * 2006-12-19 2008-06-19 Gambro Bct Inc. Apparatus for separating a composite liquid with process control on a centrifuge rotor
DE102007011332A1 (en) * 2007-03-08 2008-09-11 Fresenius Hemocare Deutschland Gmbh Device and method for separating a cell suspension, in particular for separating at least one blood component from whole blood
WO2009061488A1 (en) * 2007-11-09 2009-05-14 Wms Gaming Inc. Nvram management in a wagering game machine
US8685258B2 (en) 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
US8075468B2 (en) 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8523539B2 (en) * 2008-06-19 2013-09-03 The Board Of Regents Of The University Of Texas Systems Centrifugal pump
EP2334353A4 (en) * 2008-10-01 2013-03-27 H R D Corp Applying shear stress for disease treatment
US20110003675A1 (en) * 2009-07-06 2011-01-06 Caridianbct, Inc. Apparatus and Method for Automatically Loading Washing Solution In A Multi-Unit Blood Processor
KR20120126059A (en) * 2009-07-14 2012-11-20 엔보테크 네트워크 에스디엔 비에치디(657306-더블유) Security seal
US8456302B2 (en) 2009-07-14 2013-06-04 Savi Technology, Inc. Wireless tracking and monitoring electronic seal
EP2467812A4 (en) 2009-08-17 2014-10-22 Deal Magic Inc Contextually aware monitoring of assets
US8334773B2 (en) 2009-08-28 2012-12-18 Deal Magic, Inc. Asset monitoring and tracking system
US20110136650A1 (en) * 2009-12-08 2011-06-09 Caridianbct, Inc. Multi-Unit Blood Processor With Progressively Centered Chambers
JP5388929B2 (en) * 2010-03-31 2014-01-15 旭化成メディカル株式会社 Body fluid separation system and body fluid separation method
CN103191479B (en) * 2012-01-09 2015-04-01 金卫医疗科技(上海)有限公司 Optimization method for continuous centrifugal blood separation in curved-surface container
CN103191475B (en) * 2012-01-09 2015-04-08 金卫医疗科技(上海)有限公司 Method for continuous centrifugal blood separation in curved-surface container
WO2013109327A1 (en) 2012-01-16 2013-07-25 Fenwal, Inc. Blood bag systems for separation of whole blood and methods of use thereof
WO2013116800A2 (en) 2012-02-02 2013-08-08 Atmi Packaging, Inc. Centrifugation system and related method
USD734488S1 (en) 2014-01-24 2015-07-14 Terumo Bct, Inc. Combined centrifuge balance bag and connector
USD734487S1 (en) 2014-01-24 2015-07-14 Terumo Bct, Inc. Connector for a centrifuge balance bag
USD740958S1 (en) 2014-10-10 2015-10-13 Terumo Bct, Inc. Centrifuge counter balance bag
EP3519005B1 (en) 2016-10-03 2023-09-13 Terumo BCT, Inc. Centrifugal fluid separation device
US11013850B2 (en) * 2016-12-02 2021-05-25 Terumo Bct, Inc. Composite fluid separation
CN111801412A (en) * 2018-03-02 2020-10-20 赛默电子Led有限公司 Disposable centrifugation containers for separating biological suspensions and methods of use
CN109876495B (en) * 2019-03-27 2024-03-19 刘忠英 Component separating device
US20230285654A1 (en) * 2022-03-10 2023-09-14 Terumo Bct, Inc. Blood component collection bladder

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
JPS5586552A (en) * 1978-12-23 1980-06-30 Tomy Seikou:Kk Centrifugal separator
US4330080A (en) * 1979-11-30 1982-05-18 Dr. Eduard Fresenius, Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg Separator for an ultracentrifuge
EP1043072A1 (en) * 1999-04-09 2000-10-11 Jean-Denis Rochat Centrifuging device and use of the device

Family Cites Families (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US426275A (en) * 1890-04-22 And oscar walfrid hult
US585936A (en) * 1897-07-06 linders
US247804A (en) * 1881-10-04 Centeifugal oeeamer
US487943A (en) * 1892-12-13 Henry f
US748038A (en) * 1902-07-28 1903-12-29 John H Ayers Centrifugal liquid-separator.
US856361A (en) * 1906-05-25 1907-06-11 Gustave L Neiburg Apparatus for electrochemically and mechanically purifying liquids.
US2616619A (en) * 1948-08-30 1952-11-04 Norman A Macleod Method and apparatus for centrifugal elutriation
US2986442A (en) * 1956-07-19 1961-05-30 Century Geophysical Corp Electrophotographic oscillograph for observing slow recurrent signals
BE561760A (en) * 1956-10-19
US3190546A (en) * 1959-03-27 1965-06-22 Raccuglia Giovanni Method and apparatus for separating liquid mixtures
US3211368A (en) * 1962-11-05 1965-10-12 Giovanni Raccuglia Method and apparatus for treating liquid mixtures
US3145713A (en) 1963-09-12 1964-08-25 Protein Foundation Inc Method and apparatus for processing blood
US3311296A (en) * 1963-11-12 1967-03-28 Exxon Research Engineering Co Separation apparatus
US3304990A (en) * 1965-02-15 1967-02-21 Univ Tennessee Res Corp Explosion proof centrifugal evaporator with magnetic drive
US3655123A (en) 1966-08-08 1972-04-11 Us Health Education & Welfare Continuous flow blood separator
US3489145A (en) * 1966-08-08 1970-01-13 Surgeon General Of The Public Method and apparatus for continuous separation of blood in vivo
US3432104A (en) * 1967-03-23 1969-03-11 Theodore L Kaltenbach Seal spray gun siphon cup
US3519201A (en) 1968-05-07 1970-07-07 Us Health Education & Welfare Seal means for blood separator and the like
JPS4915339Y1 (en) * 1968-10-03 1974-04-17
US3703984A (en) * 1970-04-21 1972-11-28 Harold T Pruessner Method and apparatus of centrifugal separation
US3843046A (en) * 1971-03-29 1974-10-22 J Joyce Rotors and rotor cores for continuous flow centrifuges
US3747843A (en) * 1971-04-09 1973-07-24 Damon Corp Continuous flow zonal rotor
US3940052A (en) * 1971-11-03 1976-02-24 Mchugh Vincent Kenneth Unitary container liner
US3737096A (en) 1971-12-23 1973-06-05 Ibm Blood processing control apparatus
BE794220A (en) 1972-01-28 1973-05-16 Ibm RESERVOIR INTENDED IN PARTICULAR FOR THE TREATMENT OF BLOOD
US4934995A (en) 1977-08-12 1990-06-19 Baxter International Inc. Blood component centrifuge having collapsible inner liner
US3825175A (en) 1973-06-06 1974-07-23 Atomic Energy Commission Centrifugal particle elutriator and method of use
US3880592A (en) 1973-07-05 1975-04-29 Instrumentation Labor Inc Blood analysis system including a plasma separator
US3864089A (en) * 1973-12-10 1975-02-04 Atomic Energy Commission Multiple-sample rotor assembly for blood fraction preparation
US4059108A (en) 1974-08-15 1977-11-22 Haemonetics Corporation Process for pheresis procedure and disposable pheresis bowl therefor
US4113173A (en) 1975-03-27 1978-09-12 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing apparatus
US3957197A (en) * 1975-04-25 1976-05-18 The United States Of America As Represented By The United States Energy Research And Development Administration Centrifuge apparatus
US3955755A (en) 1975-04-25 1976-05-11 The United States Of America As Represented By The United States Energy Research And Development Administration Closed continuous-flow centrifuge rotor
US4018304A (en) 1975-10-08 1977-04-19 Baxter Travenol Laboratories, Inc. Lubrication system for a centrifugal liquid processing system
US3986442A (en) 1975-10-09 1976-10-19 Baxter Laboratories, Inc. Drive system for a centrifugal liquid processing system
US4010894A (en) 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4425112A (en) 1976-02-25 1984-01-10 The United States Of America As Represented By The Department Of Health And Human Services Flow-through centrifuge
US4734089A (en) 1976-05-14 1988-03-29 Baxter Travenol Laboratories, Inc. Centrifugal blood processing system
US4636193A (en) 1976-05-14 1987-01-13 Baxter Travenol Laboratories, Inc. Disposable centrifugal blood processing system
US4151929A (en) * 1976-07-09 1979-05-01 Sapien Sisto V Plastic liner with collar for a paint receptacle
US4086924A (en) 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus
DE2658926A1 (en) 1976-12-24 1978-06-29 Heraeus Christ Gmbh Centrifuge rotor for washing blood cells - has two formed components between which films are mounted
US4091989A (en) * 1977-01-04 1978-05-30 Schlutz Charles A Continuous flow fractionation and separation device and method
US4430072A (en) 1977-06-03 1984-02-07 International Business Machines Corporation Centrifuge assembly
US4120448A (en) 1977-06-08 1978-10-17 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing apparatus with automatically positioned collection port
US4109854A (en) 1977-06-13 1978-08-29 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with outer enclosure
US4194684A (en) 1977-06-13 1980-03-25 Baxter Travenol Laboratories, Inc. Centifugal apparatus using polyester elastomer tubing
US4120449A (en) 1977-06-13 1978-10-17 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus using tube drive
US4094461A (en) 1977-06-27 1978-06-13 International Business Machines Corporation Centrifuge collecting chamber
US4111356A (en) 1977-07-13 1978-09-05 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with flexible sheath
US4159081A (en) * 1977-07-18 1979-06-26 Scientific Energy Systems Corporation Plural valve, hand-held spray apparatus
US5006103A (en) 1977-08-12 1991-04-09 Baxter International Inc. Disposable container for a centrifuge
US5571068A (en) 1977-08-12 1996-11-05 Baxter International Inc. Centrifuge assembly
US5217426A (en) 1977-08-12 1993-06-08 Baxter International Inc. Combination disposable plastic blood receiving container and blood component centrifuge
US5217427A (en) 1977-08-12 1993-06-08 Baxter International Inc. Centrifuge assembly
US4114802A (en) 1977-08-29 1978-09-19 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with biaxial connector
US4108353A (en) 1977-08-31 1978-08-22 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with oppositely positioned rotational support means
US4191182A (en) 1977-09-23 1980-03-04 Hemotherapy Inc. Method and apparatus for continuous plasmaphersis
US4387848A (en) 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4164318A (en) 1977-10-12 1979-08-14 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus with reduced-load tubing
US4146172A (en) 1977-10-18 1979-03-27 Baxter Travenol Laboratories, Inc. Centrifugal liquid processing system
US4379452A (en) 1977-10-18 1983-04-12 Baxter Travenol Laboratories, Inc. Prepackaged, self-contained fluid circuit module
US4185629A (en) 1977-10-18 1980-01-29 Baxter Travenol Laboratories, Inc. Method and apparatus for processing blood
US4109852A (en) 1977-10-21 1978-08-29 Baxter Travenol Laboratories, Inc. Centrifugal strain relief sheath for processing apparatus
US4109855A (en) 1977-10-25 1978-08-29 Baxter Travenol Laboratories, Inc. Drive system for centrifugal processing apparatus
US4386730A (en) 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
US4187979A (en) 1978-09-21 1980-02-12 Baxter Travenol Laboratories, Inc. Method and system for fractionating a quantity of blood into the components thereof
US4245383A (en) 1978-11-08 1981-01-20 Baxter Travenol Laboratories, Inc. Centrifugal processing apparatus with reduced-load tubing
US4303193A (en) 1979-01-22 1981-12-01 Haemonetics Corporation Apparatus for separating blood into components thereof
US4216770A (en) 1979-02-09 1980-08-12 Baxter Travenol Laboratories, Inc. Sickle cell therapeutic treatment
US4226669A (en) * 1979-05-09 1980-10-07 Savant Instruments, Inc. Vacuum centrifuge with magnetic drive
SE7908036L (en) * 1979-09-28 1981-03-29 Gambro Dialysatoren Separation unit for separating liquids, SPECIAL HELD BLOOD
US4260598A (en) * 1979-10-22 1981-04-07 Pfizer Inc. Method for increasing antibacterial effectiveness of a β-lactam antibiotic
US4637813A (en) 1979-12-06 1987-01-20 Baxter Travenol Laboratories, Inc. Blood processing assembly including a prepackaged fluid circuit module
US4526515A (en) 1979-12-06 1985-07-02 Baxter Travenol Laboratories, Inc. Fluid pumping assembly including a prepackaged fluid circuit module
US4304357A (en) 1980-06-16 1981-12-08 Haemonetics Corporation Blood processing centrifuge
US4332351A (en) 1980-09-22 1982-06-01 International Business Machines Corporation Blood fraction extracting centrifuge
US4433812A (en) * 1980-11-12 1984-02-28 Champion Spark Plug Company Paint spray attachment
US4417884A (en) 1981-07-09 1983-11-29 Haemonetics Corporation Centrifuge timer clamp
US4421503A (en) 1981-07-09 1983-12-20 Haemonetics Corporation Fluid processing centrifuge and apparatus thereof
US4402680A (en) 1981-07-09 1983-09-06 Haemonetics Corporation Apparatus and method for separating fluid into components thereof
US4436631A (en) 1981-08-05 1984-03-13 Ortho Diagnostic Systems Inc. Multiple particle washing system and method of use
US4435293A (en) 1981-08-05 1984-03-06 Ortho Diagnostic Systems Inc. Particle washing system and method of use
US4416654A (en) 1981-09-03 1983-11-22 Haemonetics Corporation Pheresis apparatus
US4464167A (en) 1981-09-03 1984-08-07 Haemonetics Corporation Pheresis apparatus
US4416778A (en) 1981-10-20 1983-11-22 Neocyte, Inc. Means for preparing neocyte enriched blood
US4531932A (en) 1981-11-27 1985-07-30 Dideco S.P.A. Centrifugal plasmapheresis device
US4447221A (en) 1982-06-15 1984-05-08 International Business Machines Corporation Continuous flow centrifuge assembly
US4482342A (en) 1982-06-17 1984-11-13 Haemonetics Corporation Blood processing system for cell washing
US5034135A (en) 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US4439178A (en) 1982-12-30 1984-03-27 International Business Machines Corporation Sealless centrifuge processing channel and tube system
DE3301113C2 (en) 1983-01-14 1985-01-10 Fresenius AG, 6380 Bad Homburg Method and device for separating media
US4610846A (en) 1983-08-18 1986-09-09 Hans Martin Compartmentalized centrifugation chamber
DE3346165C2 (en) * 1983-12-21 1987-04-30 Hartmut 2905 Edewecht Ihmels Spray agent insert for spray guns
AU4152085A (en) 1984-03-21 1985-10-11 Mclaughlin, W.F. Method and apparatus for separation of matter from suspension
DE3410286C2 (en) 1984-03-21 1986-01-23 Fresenius AG, 6380 Bad Homburg Method for separating blood and device for carrying out the method
US4776964A (en) 1984-08-24 1988-10-11 William F. McLaughlin Closed hemapheresis system and method
FR2572533B1 (en) * 1984-10-26 1986-12-26 Guigan Jean METHOD FOR CARRYING OUT THE MEDICAL ANALYSIS OF A LIQUID SAMPLE USING AT LEAST ONE LIQUID REAGENT AND DEVICE FOR CARRYING OUT THE METHOD
US4879040A (en) 1984-11-15 1989-11-07 Baxter International Inc. Adaptive filter concentrate flow control system and method
US4675106A (en) 1985-04-12 1987-06-23 Hemascience Laboratories, Inc. Pivot pin bearing for biomedical systems
US4806247A (en) 1985-04-12 1989-02-21 Baxter International Inc. Plasmapheresis system and method
US4713176A (en) 1985-04-12 1987-12-15 Hemascience Laboratories, Inc. Plasmapheresis system and method
US4753729A (en) 1985-04-26 1988-06-28 Baxter Travenol Laboratories, Inc. Rotor drive for medical disposables
US4816151A (en) 1985-04-26 1989-03-28 Baxter International Inc. Rotor drive for medical disposables
US4670147A (en) 1985-08-12 1987-06-02 Schoendorfer Donald W Disposable diagnostic plasma filter dispenser
US4869812A (en) 1985-08-12 1989-09-26 Baxter International Inc. Disposable diagnostic plasma filter dispenser
GB8521867D0 (en) 1985-09-03 1985-10-09 Fisons Plc Centrifuge
US4647279A (en) 1985-10-18 1987-03-03 Cobe Laboratories, Inc. Centrifugal separator
US4755300A (en) 1985-12-23 1988-07-05 Haemonetics Corporation Couette membrane filtration apparatus for separating suspended components in a fluid medium using high shear
US4708712A (en) 1986-03-28 1987-11-24 Cobe Laboratories, Inc. Continuous-loop centrifugal separator
SE8601891D0 (en) 1986-04-24 1986-04-24 Svante Jonsson PLASMA SWITCH TREATMENT AND TROMBOCYTING MACHINE
US4990132A (en) 1986-05-16 1991-02-05 Omega Medicinteknik Ab Method and apparatus for plasmapheresis
US4804363A (en) 1986-07-16 1989-02-14 Autologous Blood Corporation Apparatus and method for storing and processing blood
USRE33924E (en) 1986-07-16 1992-05-12 Autologous Blood Corp. Apparatus and method for storing and processing blood
US4696666A (en) 1986-07-18 1987-09-29 Rice Jr Richard D Centrifuge machine and rotor
US4943273A (en) 1986-07-22 1990-07-24 Haemonetics Corporation Disposable centrifuge bowl for blood processing
US4983158A (en) 1986-07-22 1991-01-08 Haemonetics Corporation Plasmapheresis centrifuge bowl
JP2881305B2 (en) 1986-08-11 1999-04-12 バクスター、インターナショナル、インコーポレイテッド Blood cell cleaning system and method
DE3632176A1 (en) 1986-09-22 1988-04-07 Fresenius Ag CONTROL OF A SYSTEM FOR SEPARATING THE COMPONENTS OF BLOOD TAKEN FROM A DONOR "IN VIVO"
DE3632500A1 (en) 1986-09-24 1988-04-07 Fresenius Ag CENTRIFUGAL ARRANGEMENT
US4944883A (en) 1987-01-13 1990-07-31 Schoendorfer Donald W Continuous centrifugation system and method for directly deriving intermediate density material from a suspension
US4824431A (en) * 1987-01-13 1989-04-25 Mcalister Steven A Centrifugal concentrator
US5053127A (en) 1987-01-13 1991-10-01 William F. McLaughlin Continuous centrifugation system and method for directly deriving intermediate density material from a suspension
US5370802A (en) 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US5104526A (en) 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US4834890A (en) 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US4940543A (en) 1987-01-30 1990-07-10 Baxter International Inc. Plasma collection set
US4738655A (en) 1987-06-17 1988-04-19 Utah Bioresearch, Inc. Apparatus and method for obtaining a rapid hematocrit
US4850995A (en) 1987-08-19 1989-07-25 Cobe Laboratories, Inc. Centrifugal separation of blood
US4889524A (en) * 1987-09-04 1989-12-26 Haemonetics Corporation Portable centrifuge apparatus
SE462015B (en) 1987-09-15 1990-04-30 Omega Medicinteknik Ab SETTING AND DEVICE CLEANING BLOOD CELLS
US4850998A (en) 1987-10-07 1989-07-25 Baxter International Inc. Method for wetting a plasmapheresis filter with anticoagulant
US4851126A (en) 1987-11-25 1989-07-25 Baxter International Inc. Apparatus and methods for generating platelet concentrate
DE3817664A1 (en) * 1988-05-25 1989-11-30 Josef Dr Theissen Method and device for lavage of blood cells
US4935002A (en) 1988-06-29 1990-06-19 Biodynamics, Inc. Apparatus and method for the autotransfusion of blood
US4986158A (en) * 1989-02-23 1991-01-22 Johnson Stefan J Modular multiple musical instrument stand
US5045048A (en) * 1990-03-29 1991-09-03 Haemonetics Corporation Rotary centrifuge bowl and seal for blood processing
US5061381A (en) 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5186844A (en) * 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5135667A (en) 1990-06-14 1992-08-04 Baxter International Inc. Method and apparatus for administration of anticoagulant to red cell suspension output of a blood separator
US5171456A (en) 1990-06-14 1992-12-15 Baxter International Inc. Automated blood component separation procedure and apparatus promoting different functional characteristics in multiple blood components
SE9002255D0 (en) * 1990-06-26 1990-06-26 Eric Westberg METHOD AND APPARATUS FOR THE PREPARATION OF BLOOD
FR2665378B1 (en) 1990-08-03 1992-10-09 Guigan Jean DEVICE FOR SEPARATING BY CENTRIFUGATION TWO PHASES FROM A SAMPLE OF A HETEROGENEOUS LIQUID, USABLE IN PARTICULAR FOR THE SEPARATION OF TOTAL BLOOD PLASMA.
US5641622A (en) 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5211808A (en) * 1990-11-13 1993-05-18 Savant Instruments Microwave heating in a vacuum centrifugal concentrator
US5275731A (en) 1991-06-28 1994-01-04 Jahn Karl H Apparatus for rapidly separating blood into filtered fractions
DE4126341C1 (en) 1991-08-09 1993-01-28 Fresenius Ag, 6380 Bad Homburg, De
DE4129516C2 (en) 1991-09-06 2000-03-09 Fresenius Ag Method and device for separating blood into its components
DE4132965A1 (en) 1991-10-04 1993-04-08 Fresenius Ag DEVICE FOR SEPARATING MEDIA IN ITS COMPONENTS
US6319471B1 (en) 1992-07-10 2001-11-20 Gambro, Inc. Apparatus for producing blood component products
US5421812A (en) 1992-03-04 1995-06-06 Cobe Laboratories, Inc. Method and apparatus for controlling concentrations in tubing system
US5295953A (en) 1992-05-26 1994-03-22 Hemagen/Pfc Method and apparatus for extracorporeal separation of fluorochemicals from whole blood of a patient
DE4226974C2 (en) 1992-08-14 1994-08-11 Fresenius Ag Method and device for the continuous preparation of a cell suspension
US5209365A (en) * 1992-09-01 1993-05-11 Devilbiss Air Power Company Paint cup lid assembly
WO1994008721A1 (en) 1992-10-13 1994-04-28 Haemonetics Corporation Disposable centrifuge rotor and core
US5614106A (en) 1993-03-12 1997-03-25 Baxter International Inc. Method and apparatus for collection of platelets
DE69425966T2 (en) 1993-04-27 2001-03-29 Haemonetics Corp., Braintree Apheresis device
SE9302369D0 (en) 1993-07-08 1993-07-08 Omega Medicinteknik Ab PASS SYSTEM PROVIDED FOR CENTRIFUGAL SEPARATION WITH USE OF THIS PASS SYSTEM
US5524795A (en) * 1994-04-14 1996-06-11 Lee; Gary K. Dispensing unit for a threaded neck bottle
US5733253A (en) 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US5651766A (en) 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US5569410A (en) * 1994-11-17 1996-10-29 Elf Atochem North America, Inc. Ammonium bicarbonate/ammonium carbamate activated benzyl alcohol paint stripper
US5704889A (en) 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
US5704888A (en) 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
EP0824380B1 (en) 1995-04-18 2002-01-09 Gambro, Inc., Particle separation method
US5674173A (en) 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
US6053856A (en) 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
US5951877A (en) 1995-04-18 1999-09-14 Cobe Laboratories, Inc. Particle filter method
DE19515891C2 (en) * 1995-04-29 1999-10-28 Roche Diagnostics Gmbh Genus and species-specific identification of Legionella
US5653887A (en) 1995-06-07 1997-08-05 Cobe Laboratories, Inc. Apheresis blood processing method using pictorial displays
US5702357A (en) 1995-06-07 1997-12-30 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5738644A (en) 1995-06-07 1998-04-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
JP3313572B2 (en) 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション Blood processing centrifuge bowl
US5792038A (en) 1996-05-15 1998-08-11 Cobe Laboratories, Inc. Centrifugal separation device for providing a substantially coriolis-free pathway
EP0907420B1 (en) 1996-05-15 2000-08-30 Gambro, Inc., Method and apparatus for reducing turbulence in fluid flow
DE19701551C1 (en) 1997-01-17 1998-08-06 Fresenius Ag Centrifuge rotor imbalance detector
SE9701423D0 (en) 1997-04-16 1997-04-16 Omega Medicinteknik Ab Container set and device for blood separation
US6200287B1 (en) 1997-09-05 2001-03-13 Gambro, Inc. Extracorporeal blood processing methods and apparatus
DE19801767C1 (en) 1998-01-19 1999-10-07 Fresenius Ag centrifuge
DE19803534C2 (en) 1998-01-30 1999-11-11 Fresenius Ag Centrifuge and line for supplying and / or discharging at least one fluid from the separation unit of a centrifuge to a fixed connection point
US6012651A (en) * 1998-04-10 2000-01-11 Spitznagel; Max W. A. Gravity-fed spray gun assembly
DE19841835C2 (en) 1998-09-12 2003-05-28 Fresenius Ag Centrifuge chamber for a cell separator
SE513440C2 (en) * 1999-01-27 2000-09-11 Alfa Laval Ab Outlet at centrifugal separator with reaction driven rotor
US6334842B1 (en) 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6296602B1 (en) 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
DE29909950U1 (en) * 1999-06-08 1999-09-23 Chang, Jen-Chih, Taichung Spray gun container
US6536687B1 (en) * 1999-08-16 2003-03-25 3M Innovative Properties Company Mixing cup adapting assembly
US6325775B1 (en) 1999-09-03 2001-12-04 Baxter International Inc. Self-contained, transportable blood processsing device
US6322488B1 (en) 1999-09-03 2001-11-27 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US6315707B1 (en) 1999-09-03 2001-11-13 Baxter International Inc. Systems and methods for seperating blood in a rotating field
US6189809B1 (en) * 1999-09-23 2001-02-20 Illinois Tool Works Inc. Multi-feed spray gun
EP1363739B1 (en) * 2000-11-02 2011-12-21 CaridianBCT, Inc. Fluid separation devices, systems and methods
US6588681B2 (en) * 2001-07-09 2003-07-08 3M Innovative Properties Company Liquid supply assembly

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
JPS5586552A (en) * 1978-12-23 1980-06-30 Tomy Seikou:Kk Centrifugal separator
US4330080A (en) * 1979-11-30 1982-05-18 Dr. Eduard Fresenius, Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg Separator for an ultracentrifuge
EP1043072A1 (en) * 1999-04-09 2000-10-11 Jean-Denis Rochat Centrifuging device and use of the device

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 004, no. 135 (C - 025) 20 September 1980 (1980-09-20) *

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