WO2002060396A3 - Hair follicle neogenesis by injection of follicle progenitor cells - Google Patents

Hair follicle neogenesis by injection of follicle progenitor cells Download PDF

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Publication number
WO2002060396A3
WO2002060396A3 PCT/US2002/002643 US0202643W WO02060396A3 WO 2002060396 A3 WO2002060396 A3 WO 2002060396A3 US 0202643 W US0202643 W US 0202643W WO 02060396 A3 WO02060396 A3 WO 02060396A3
Authority
WO
WIPO (PCT)
Prior art keywords
follicle
progenitor cells
injection
neogenesis
hair
Prior art date
Application number
PCT/US2002/002643
Other languages
French (fr)
Other versions
WO2002060396A2 (en
Inventor
Thomas H Barrows
Original Assignee
Bioamide Inc
Thomas H Barrows
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioamide Inc, Thomas H Barrows filed Critical Bioamide Inc
Priority to MXPA03006714A priority Critical patent/MXPA03006714A/en
Priority to BR0206796-0A priority patent/BR0206796A/en
Priority to KR10-2003-7009943A priority patent/KR20030082576A/en
Priority to CA002435709A priority patent/CA2435709A1/en
Priority to JP2002560590A priority patent/JP2004517934A/en
Priority to US10/470,389 priority patent/US20040068284A1/en
Priority to EP02703283A priority patent/EP1367982A2/en
Publication of WO2002060396A2 publication Critical patent/WO2002060396A2/en
Publication of WO2002060396A3 publication Critical patent/WO2002060396A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/10—Hair or skin implants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0627—Hair cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Methods and devices are disclosed for use in the treatment of male pattern baldness and other conditions involving hair loss by facilitating the growth of new hair in the dermis of a living subject. The method involves the steps of atraumatically injecting follicle progenitor cells into the interface between the dermis and the epidermis and allowing the cells to grow into new hair follicles.
PCT/US2002/002643 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells WO2002060396A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
MXPA03006714A MXPA03006714A (en) 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells.
BR0206796-0A BR0206796A (en) 2001-01-29 2002-01-29 Hair follicle neogenesis through injection of follicle generating cells
KR10-2003-7009943A KR20030082576A (en) 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells
CA002435709A CA2435709A1 (en) 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells
JP2002560590A JP2004517934A (en) 2001-01-29 2002-01-29 Hair follicle formation by injection of hair follicle precursor cells
US10/470,389 US20040068284A1 (en) 2002-01-29 2002-01-29 Method for stimulating hair growth and kit for carrying out said method
EP02703283A EP1367982A2 (en) 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26480601P 2001-01-29 2001-01-29
US60/264,806 2001-01-29

Publications (2)

Publication Number Publication Date
WO2002060396A2 WO2002060396A2 (en) 2002-08-08
WO2002060396A3 true WO2002060396A3 (en) 2003-03-13

Family

ID=23007681

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/002643 WO2002060396A2 (en) 2001-01-29 2002-01-29 Hair follicle neogenesis by injection of follicle progenitor cells

Country Status (8)

Country Link
EP (1) EP1367982A2 (en)
JP (1) JP2004517934A (en)
KR (1) KR20030082576A (en)
CN (1) CN1553793A (en)
BR (1) BR0206796A (en)
CA (1) CA2435709A1 (en)
MX (1) MXPA03006714A (en)
WO (1) WO2002060396A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9023380B2 (en) 2005-11-22 2015-05-05 Aderans Research Institute, Inc. Hair follicle graft from tissue engineered skin

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030161815A1 (en) 2002-02-12 2003-08-28 Intercytex Limited Cell delivery system
US20030198646A1 (en) * 2002-04-17 2003-10-23 Stenn Kurt Stricker Compositions and methods for inducing new hair follicle formation and hair growth in a desired orientation
WO2004044188A1 (en) 2002-11-14 2004-05-27 Intercytex Limited Cultivation of hair inductive cells
CN1842355A (en) * 2003-08-26 2006-10-04 阿尔扎公司 Device and method for intradermal cell implantation
US7597885B2 (en) * 2004-03-26 2009-10-06 Aderans Research Institute, Inc. Tissue engineered biomimetic hair follicle graft
AU2012204059B2 (en) * 2005-03-29 2015-01-15 The Trustees Of The University Of Pennsylvania Methods for generating new hair follicles, treating baldness and hair removal
JP2008537940A (en) * 2005-03-29 2008-10-02 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア Methods for forming new hair follicles, treating baldness, and removing hair
JP5263756B2 (en) 2005-09-30 2013-08-14 国立大学法人 岡山大学 Cell culture method and cell culture
EP1945757B1 (en) * 2005-10-17 2017-12-06 Aderans Research Institute, Inc. Method of delivering hair follicle progenitor cells to the skin
US7780635B2 (en) 2006-02-09 2010-08-24 Aderans Research Institute, Inc. Apparatus and methods for delivering fluid and material to a subject
GB0605450D0 (en) 2006-03-17 2006-04-26 Intercytex Ltd Cell co-culture
CA2664697A1 (en) 2006-09-28 2008-04-10 Follica, Inc. Methods, kits, and compositions for generating new hair follicles and growing hair
BR112013014021A8 (en) 2010-12-06 2017-10-03 Follica Inc METHODS FOR TREATMENT OF BALDNESS AND PROMOTION OF HAIR GROWTH
EP2937098A1 (en) * 2014-04-24 2015-10-28 Clinica Dermatologica Ercilla A pharmaceutical composition comprising a suspension of total cells obtained from hair follicle and plasma derived growth factors for promoting hair follicle regeneration
CN112153957B (en) * 2018-04-13 2023-12-26 北卡罗来纳州立大学 Use of microneedle patch for promoting hair growth
JP2020130771A (en) * 2019-02-22 2020-08-31 キヤノン株式会社 Processing device, processing method and program
CN109908179A (en) * 2019-03-08 2019-06-21 广西医科大学第一附属医院 A kind of injection medicament of hair follicle progenitor cells
CN111840330B (en) * 2020-08-03 2022-04-22 诺赛联合(北京)生物医学科技有限公司 Anti-hair loss repairing composition and application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0236014A1 (en) * 1986-02-21 1987-09-09 University of Dundee Stimulation of hair growth
WO1999001034A1 (en) * 1997-07-01 1999-01-14 Cooley Jerry E Method for producing new hair growth
WO2001058413A1 (en) * 2000-02-08 2001-08-16 Klaus Rennebeck Method for stimulating hair growth and kit for carrying out said method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0236014A1 (en) * 1986-02-21 1987-09-09 University of Dundee Stimulation of hair growth
WO1999001034A1 (en) * 1997-07-01 1999-01-14 Cooley Jerry E Method for producing new hair growth
WO2001058413A1 (en) * 2000-02-08 2001-08-16 Klaus Rennebeck Method for stimulating hair growth and kit for carrying out said method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JAHODA C A B ET AL: "DERMAL-EPIDERMAL INTERACTIONS. ADULT FOLLICLE-DERIVED CELL POPULATIONS AND HAIR GROWTH", DERMATOLOGIC CLINICS, W.B. SAUNDERS CO., LONDON, GB, vol. 14, no. 4, October 1996 (1996-10-01), pages 573 - 583, XP002913549, ISSN: 0733-8635 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9023380B2 (en) 2005-11-22 2015-05-05 Aderans Research Institute, Inc. Hair follicle graft from tissue engineered skin

Also Published As

Publication number Publication date
EP1367982A2 (en) 2003-12-10
MXPA03006714A (en) 2005-04-08
KR20030082576A (en) 2003-10-22
BR0206796A (en) 2004-02-03
JP2004517934A (en) 2004-06-17
WO2002060396A2 (en) 2002-08-08
CA2435709A1 (en) 2002-08-08
CN1553793A (en) 2004-12-08

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