WO2002055189A3 - Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics - Google Patents

Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics Download PDF

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Publication number
WO2002055189A3
WO2002055189A3 PCT/US2002/000993 US0200993W WO02055189A3 WO 2002055189 A3 WO2002055189 A3 WO 2002055189A3 US 0200993 W US0200993 W US 0200993W WO 02055189 A3 WO02055189 A3 WO 02055189A3
Authority
WO
WIPO (PCT)
Prior art keywords
reactions
miniaturized
subject matter
nanoporous membrane
methods
Prior art date
Application number
PCT/US2002/000993
Other languages
French (fr)
Other versions
WO2002055189A2 (en
Inventor
Andras Guttman
Zsolt Ronai
Csaba Barta
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Priority to AU2002239908A priority Critical patent/AU2002239908A1/en
Priority claimed from US10/047,461 external-priority patent/US20030132117A1/en
Publication of WO2002055189A2 publication Critical patent/WO2002055189A2/en
Publication of WO2002055189A3 publication Critical patent/WO2002055189A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Electrochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous membrane environment. The subject matter contemplates methods for modifying the kinetics of reactions and devices for conducting reactions having modified kinetics. The subject matter also provides systems for rapid miniaturized reactions. Further the subject matter includes methods and kits for conducting a reaction with enhanced throughput and methods of conducting miniaturized, high throughput analyses of reaction products, and the like. Reactions performed on or within a nanoporous membrane exhibits improved kinetic characteristics.
PCT/US2002/000993 2001-01-12 2002-01-14 Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics WO2002055189A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002239908A AU2002239908A1 (en) 2001-01-12 2002-01-14 Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75998901A 2001-01-12 2001-01-12
US09/759,989 2001-01-12
US10/047,461 US20030132117A1 (en) 2002-01-14 2002-01-14 Thin film electrophoresis apparatus and method
US10/047,461 2002-01-14

Publications (2)

Publication Number Publication Date
WO2002055189A2 WO2002055189A2 (en) 2002-07-18
WO2002055189A3 true WO2002055189A3 (en) 2004-10-28

Family

ID=26725040

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2002/000985 WO2002056004A2 (en) 2001-01-12 2002-01-14 Thin film electrophoresis apparatus and method
PCT/US2002/000993 WO2002055189A2 (en) 2001-01-12 2002-01-14 Nanoporous membrane reactor for miniaturized reactions and enhanced reaction kinetics

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000985 WO2002056004A2 (en) 2001-01-12 2002-01-14 Thin film electrophoresis apparatus and method

Country Status (3)

Country Link
AU (1) AU2002239908A1 (en)
CA (1) CA2434469A1 (en)
WO (2) WO2002056004A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005029062A2 (en) * 2003-09-22 2005-03-31 Shimadzu Corporation Electrophoretic member electrophoretic device electrophoretic method and sample dispensing probe
GB2439233B (en) * 2003-09-22 2008-04-23 Shimadzu Corp An electrophoretic separation method
CN100447567C (en) * 2004-09-22 2008-12-31 杭州生源医疗保健技术开发有限公司 Composite ionic membrane micro electric chromatography
US8206974B2 (en) 2005-05-19 2012-06-26 Netbio, Inc. Ruggedized apparatus for analysis of nucleic acid and proteins
CA2984820C (en) 2007-04-04 2021-12-07 Ande Corporation Plastic microfluidic separation and detection platforms
US8901487B2 (en) 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
US8067730B2 (en) 2007-07-20 2011-11-29 The George Washington University Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry
US7964843B2 (en) 2008-07-18 2011-06-21 The George Washington University Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry
JP2012529908A (en) 2009-06-15 2012-11-29 ネットバイオ・インコーポレーテッド Improved method for quantification of forensic DNA
JP2014524121A (en) 2011-07-14 2014-09-18 ザ・ジョージ・ワシントン・ユニバーシティ Plume collimation for laser ablation and electrospray ionization mass spectrometry
GB2502953B (en) 2012-05-24 2017-02-08 Imp Innovations Ltd Catalytic converter substrate
NL2009191C2 (en) * 2012-07-16 2014-01-20 Univ Delft Tech Single molecule protein sequencing.
GB2517951A (en) 2013-09-05 2015-03-11 Imp Innovations Ltd A substrate and a method of manufacturing a substrate
US10115577B1 (en) * 2017-09-07 2018-10-30 California Institute Of Technology Isotope ratio mass spectrometry

Citations (3)

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US5990373A (en) * 1996-08-20 1999-11-23 Kansas State University Research Foundation Nanometer sized metal oxide particles for ambient temperature adsorption of toxic chemicals
US6015714A (en) * 1995-03-17 2000-01-18 The United States Of America As Represented By The Secretary Of Commerce Characterization of individual polymer molecules based on monomer-interface interactions
US6057488A (en) * 1998-09-15 2000-05-02 Nantek, Inc. Nanoparticles for the destructive sorption of biological and chemical contaminants

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US4588491A (en) * 1984-02-27 1986-05-13 International Biotechnologies, Inc. Horizontal gel electrophoresis device
US5137613A (en) * 1990-12-20 1992-08-11 Wisconsin Alumni Research Foundation Horizontal gel electrophoresis apparatus
FR2671290B1 (en) * 1991-01-04 1993-04-16 Sebia Sa DEVICE FOR APPLYING BIOLOGICAL SAMPLES TO AN ELECTROPHORESIS PLATE.
US5338426A (en) * 1992-08-28 1994-08-16 Applied Biosystems, Inc. Horizontal polyacrylamide gel electrophoresis
WO2000065336A1 (en) * 1999-04-26 2000-11-02 Mj Research, Inc. Electrophoresis assembly and method of casting electrophoresis gels
GB2353866B (en) * 1999-05-06 2003-12-03 Univ Southampton Gel electrophoresis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015714A (en) * 1995-03-17 2000-01-18 The United States Of America As Represented By The Secretary Of Commerce Characterization of individual polymer molecules based on monomer-interface interactions
US5990373A (en) * 1996-08-20 1999-11-23 Kansas State University Research Foundation Nanometer sized metal oxide particles for ambient temperature adsorption of toxic chemicals
US6057488A (en) * 1998-09-15 2000-05-02 Nantek, Inc. Nanoparticles for the destructive sorption of biological and chemical contaminants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEAMER D W ET AL: "Nanopores and nucleic acids: prospects for ultrarapid sequencing", TRENDS IN BIOTECHNOLOGY, ELSEVIER, AMSTERDAM, NL, vol. 18, no. 4, April 2000 (2000-04-01), pages 147 - 151, XP004194002, ISSN: 0167-7799 *
KASIANOWICZ JOHN J ET AL: "Characterization of individual polynucleotide molecules using a membrane channel", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, November 1996 (1996-11-01), pages 13770 - 13773, XP002139846, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2002055189A2 (en) 2002-07-18
WO2002056004A2 (en) 2002-07-18
WO2002056004A3 (en) 2004-02-19
AU2002239908A1 (en) 2002-07-24
CA2434469A1 (en) 2002-07-18
WO2002056004A8 (en) 2003-01-16

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