WO2002051335A1 - Stent intravasculaire implantable - Google Patents

Stent intravasculaire implantable Download PDF

Info

Publication number
WO2002051335A1
WO2002051335A1 PCT/CA2000/001577 CA0001577W WO02051335A1 WO 2002051335 A1 WO2002051335 A1 WO 2002051335A1 CA 0001577 W CA0001577 W CA 0001577W WO 02051335 A1 WO02051335 A1 WO 02051335A1
Authority
WO
WIPO (PCT)
Prior art keywords
stent
connectors
modules
annular
filaments
Prior art date
Application number
PCT/CA2000/001577
Other languages
English (en)
Inventor
Kito Tosetti
Robert Gordon Ian Brown
Gary Bernhard Jenne
Mao-Jung Maurice Lien
Original Assignee
Mivi Technologies Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mivi Technologies Inc. filed Critical Mivi Technologies Inc.
Priority to PCT/CA2000/001577 priority Critical patent/WO2002051335A1/fr
Publication of WO2002051335A1 publication Critical patent/WO2002051335A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91508—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a difference in amplitude along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91583—Adjacent bands being connected to each other by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/0054—V-shaped

Definitions

  • This application relates to an improved intravascular stent for deployment in a body lumen, such as a blood vessel.
  • the stent is useful in the treatment of atherosclerotic stenosis.
  • Cardiovascular disease is the leading cause of death in the United States and Canada.
  • the disease state is commonly caused by the gradual deposition of fatty plague within the coronary arteries , resulting in a narrowing of the coronary arteries and a corresponding decrease in blood flow to heart muscles .
  • Narrowing of the coronary arteries is termed "atherosclerosis" and may trigger serious clinical complications, such as angina or myocardial infarction.
  • Stents are small tubular devices, typically constructed from biocompatible metal, which are inserted in blood vessels and the like to maintain the patency of the vessel lumen. Once deployed, stents radially support a segment of the vessel wall and help prevent atherosclerotic plague from occluding the lumen.
  • Stents are commonly deployed by means of a coronary balloon dilation catheter. This procedure involves mounting a compressed stent around an expandable balloon positioned at the distal end of a thin- walled intravascular catheter. The catheter is carefully guided by the physician to the desired location while monitoring the procedure on a video screen. For example, the catheter may be inserted into the femoral artery of the patient and progressively advanced into the iliac artery, ascending aorta and finally into the coronary artery. Once the catheter is advanced to the desired location, the physician dilates the balloon to flatten plague deposits and expand the stent from the compressed configuration to a fully expanded configuration supporting the vessel wall. The balloon is then deflated and the catheter is withdrawn from the patient.
  • stents In order to be effective, stents must exhibit both longitudinal flexibility and radial rigidity. Flexibility is necessary to permit the physician to readily guide the catheter through the twists and turns of blood vessel passageways when deploying the splint. Radial rigidity is desired to ensure that, once deployed, the splint will have the mechanical rigidity to maintain the patency of the vessel lumen, h other words, the splint must be capable of effectively resisting stenosis which is the chronic or acute occlusion of the coronary arteries following balloon angioplasty.
  • the '306 application describes a modular stent which is fabricated from wire strands.
  • Each module includes first and second wire segments which are annular in shape and are formed in a sinusoidal pattern.
  • the wire segments of each module are fastened together at two opposed locations by metal clips.
  • the modules are connected together by connecting elements which extend between the clips of adjacent modules.
  • the '306 stent is a significant improvement over conventional stent designs, it suffers from several shortcomings. Since the stent modules are joined by only one or two connecting elements, small gaps are present between the modules. These gaps in the stent scaffold permit prolapse of plaque deposits in some patients, which may lead to restenosis. The gaps are particularly problematic at locations where the stented blood vessel curves (and hence the length between adjacent modules is increased).
  • the use of metal clips to secure the two annular segments of each stent module together can also be problematic. Since the clips project outwardly a short distance from the remainder of the stent outer surface, there is a risk that the clips will tear vascular tissue during deployment of the stent within a vessel lumen. Also, during expansion of the stent at the target site, the edges of the clips may puncture the balloon used in the balloon dilation catheter procedure. Moreover, since the clips increase the effective diameter of the stent, they also impede its "trackability", namely the capacity of a physician to safely guide the stent through tortuous blood vessels to the target site. Many clinically significant lesions occur in blood vessels having a very small effective diameter and hence it is desirable to minimize the cross-sectional profile of the stent wherever possible.
  • the size and position of the clip connectors also prevents the stent from expanding symmetrically, resulting in a deployed stent which is not perfectly cylindrical. This can adversely affect the hemodynamics of the rehaped blood vessel in question and cause the gradual formation of fibrines.
  • the clip connectors define a very small cavity surrounding the coupled wire filaments, they may trap bacteria or chemicals during the manufacturing process, potentially resulting in adverse complications in vivo. Further, the crimped clip connectors are sensitive to metal fatigue over time which may compromise the functional longevity of the stent scaffold.
  • a stent comprising a plurality of expandable stent modules.
  • Each of the modules preferably comprises first and second annular elements each comprising thin filaments formed in an undulating pattern comprising alternating peaks and troughs.
  • a plurality of first connectors secure the first and annular second elements together in radial alignment to define a cylindrical opening.
  • a plurality of second connectors are also provided for joining adjacent pairs of stent modules together at radially spaced locations.
  • the second connectors are extensible between contracted and extended configurations to allow the stent to conform to curves in the vessel wall during deployment of the stent and prevent foreshortening.
  • the second connectors are serpentine-shaped in the contracted configuration.
  • Each second connector has a first end and a second end which are joined to the module filaments mid-way between one of the peaks and one of the troughs.
  • each stent module may include a pair of first connectors located on opposite sides of the module.
  • the first connectors do not deform when the stent is expanded and they may be used as substrate for delivery of drugs to the target lesion.
  • the first connectors have a relatively large surface area for drug delivery and enhanced radiopacity . Both the first and second connectors are flush with the cylindrical profile of the remainder of the stent for improved trackability and deployment.
  • Figure 1 is first perspective view of the applicant's stent comprising four separate stent modules
  • Figure 2 is a second perspective view thereof showing the stent rotated approximately 45 degrees relative to the view of Figure 1;
  • Figure 3 is a third perspective view thereof showing the stent rotated approximately 90 degrees relative to the view of Figure 1;
  • Figure 4 is an enlarged perspective end view of the stent of Figure 3;
  • Figure 5 is a plan view of the applicant's stent showing the stent cut lengthwise and laid in a flat configuration for the purpose of clarity;
  • Figures 6A - 6D are side elevational views, in three dimensions, of semi-cylindrical portions of the applicant's stent wrapped around a cylinder for the purposes of clarity.
  • stent 100 of the present appUcation is preferably formed from smaU diameter biocompatible steel tubing by a laser cutting manufacturing process rather than by wire forming.
  • stent 100 has smooth, cylindrical inner and outer surfaces which define an opening 102 having a consistent diameter.
  • stent 100 comprises a pluraUty of interconnected modules 110 defining opening 102.
  • Each module 110 consists of a pair of generaUy annular elements 112 comprising thin metal filaments 114.
  • Filaments 114 are preferably formed in an undulating 5 pattern, such as a sinusoidal wave pattern comprising alternating peaks 116 and troughs 118.
  • Elements 112 are disposed such that the peaks 116 of one element 112 are located adjacent the troughs 118 of the other element 112 (and vice versa).
  • each module 110 elements 112 are joined by a pair of opposed first connectors 120.
  • each first connector 120 is generaUy disk-shaped.
  • connectors 120 are the same thickness as filaments 114 and hence they do not protrude from the inner or outer
  • each stent module has a consistent cross-sectional profile which is important for ease of deployment.
  • first connectors 120 are not critical, it 20 preferable that they have a relatively large, non-deformable surface area to serve as a substrate for deUvery of drugs to the site of the target lesion.
  • connectors 120 could be coated with anti-restenosis drugs.
  • connectors 120 are not stretchable, such coatings wiU not splinter or peel when stent 100 is expanded at the site of the target lesion unlike some 25 prior art drug deUvery systems.
  • additional first connectors 120 could be distributed at different locations in stent 100 for targeted drug deUvery or homogenous diffusion of drugs along the vessel wall.
  • First connectors 120 may also function as improved radio- opaque markers enabling physicians to better visualize the position of stent 100 during deployment within vascular or other body lumens.
  • connectors 120 may be plated with a dense material easily visible using fluroscopy.
  • Modules 110 are interconnected by a pluraUty of extensible second connectors 126.
  • Each second connector 126 is serpentine in shape in its contracted configuration comprising generally linear end portions 122 and a generaUy S-shaped central portion 124.
  • each end portion 122 is connected to a filament 114 mid-way between a peak 116 and trough 118 and central portion 124 is disposed in the space between adjacent modules 110.
  • second connectors 126 are moveable to an extended configuration. For example, if stent 100 is deployed at a curve in the vessel lumen, some of the second connectors 126 wiU extend in length to enable stent 100 to conform to the contour of the vessel.
  • Each module 112 is independently expandable to conform to the particular anatomy of the target site. Since second connectors 126 are extensible, they prevent foreshortening of stent 100 (i.e. a reduction in the overall length of stent 100 as individual modules 112 are radially expanded).
  • second connectors 126 extend between stent modules 110 at spaced locations.
  • Connectors 126 strengthen the overall stent scaffold and help prevent prolapse of atherosclerotic plaque or vascular tissue at locations between the modules 110.

Abstract

L'invention concerne un stent intravasculaire implantable amélioré comprenant une pluralité de modules de stent extensibles. Chacun des modules comprend, de préférence, un premier et un second éléments annulaires extensibles, chaque élément étant constitué d'éléments fins formés selon un motif ondulé présentant une alternance de bosses et de creux. Une pluralité de premiers connecteurs attachent les premier et second éléments annulaires ensemble selon un alignement radial afin de définir une ouverture cylindrique. Une pluralité de seconds connecteurs permettent d'assembler des paires adjacentes de modules de stent selon un alignement radial, au niveau d'emplacements radialement espacés. Les seconds connecteurs sont extensibles entre des configurations rétractée et déployée afin de permettre audit stent d'épouser les courbes d'une paroi de vaisseau pendant le déploiement dudit stent et de prévenir un effet de raccourci. Ces seconds connecteurs permettent également d'inhiber le prolapsus d'une plaque athérosclérotique ou d'un tissu vasculaire au niveau d'emplacements situés entre les modules.
PCT/CA2000/001577 2000-12-27 2000-12-27 Stent intravasculaire implantable WO2002051335A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CA2000/001577 WO2002051335A1 (fr) 2000-12-27 2000-12-27 Stent intravasculaire implantable

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CA2000/001577 WO2002051335A1 (fr) 2000-12-27 2000-12-27 Stent intravasculaire implantable

Publications (1)

Publication Number Publication Date
WO2002051335A1 true WO2002051335A1 (fr) 2002-07-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2000/001577 WO2002051335A1 (fr) 2000-12-27 2000-12-27 Stent intravasculaire implantable

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012035550A3 (fr) * 2010-09-13 2012-12-06 Meril Life Sciences Pvt Ltd. Stents présentant une faible épaisseur d'entretoise et une géométrie d'entretoise variable
US8915954B2 (en) 2003-05-06 2014-12-23 Abbott Laboratories Endoprosthesis having foot extensions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0888757A1 (fr) * 1997-06-30 1999-01-07 Corotec Medizintechnik GmbH Implant intraluminaire
WO1999017680A1 (fr) * 1997-10-03 1999-04-15 Localmed, Inc. Support vasculaire extensible de maniere radiale avec poutres et joints de dilatation
WO2000027306A1 (fr) 1998-11-09 2000-05-18 Mivi Technologies Inc. Stent extensible et son procede de fabrication
US6083259A (en) * 1998-11-16 2000-07-04 Frantzen; John J. Axially non-contracting flexible radially expandable stent
WO2000045744A1 (fr) * 1999-02-03 2000-08-10 Boston Scientific Limited Procede de protection de surface pour extenseurs et catheters a ballonnet d'administration medicamenteuse

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0888757A1 (fr) * 1997-06-30 1999-01-07 Corotec Medizintechnik GmbH Implant intraluminaire
WO1999017680A1 (fr) * 1997-10-03 1999-04-15 Localmed, Inc. Support vasculaire extensible de maniere radiale avec poutres et joints de dilatation
WO2000027306A1 (fr) 1998-11-09 2000-05-18 Mivi Technologies Inc. Stent extensible et son procede de fabrication
US6083259A (en) * 1998-11-16 2000-07-04 Frantzen; John J. Axially non-contracting flexible radially expandable stent
WO2000045744A1 (fr) * 1999-02-03 2000-08-10 Boston Scientific Limited Procede de protection de surface pour extenseurs et catheters a ballonnet d'administration medicamenteuse

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8915954B2 (en) 2003-05-06 2014-12-23 Abbott Laboratories Endoprosthesis having foot extensions
WO2012035550A3 (fr) * 2010-09-13 2012-12-06 Meril Life Sciences Pvt Ltd. Stents présentant une faible épaisseur d'entretoise et une géométrie d'entretoise variable
CN103249380A (zh) * 2010-09-13 2013-08-14 美利奴生命科学有限公司 具有低支柱厚度及可变支柱几何的支架
JP2013539661A (ja) * 2010-09-13 2013-10-28 メリル ライフ サイエンシズ ピーブィティ．エルティディ 薄ストラット厚および可変ストラット形状を有するステント
CN103249380B (zh) * 2010-09-13 2015-10-21 美利奴生命科学有限公司 具有低支柱厚度及可变支柱几何的支架

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