WO2002050098A2 - Haplotypes du gene du recepteur de la prolactine (prlr) - Google Patents

Haplotypes du gene du recepteur de la prolactine (prlr) Download PDF

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Publication number
WO2002050098A2
WO2002050098A2 PCT/US2001/049049 US0149049W WO0250098A2 WO 2002050098 A2 WO2002050098 A2 WO 2002050098A2 US 0149049 W US0149049 W US 0149049W WO 0250098 A2 WO0250098 A2 WO 0250098A2
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WO
WIPO (PCT)
Prior art keywords
prlr
haplotype
seq
gene
individual
Prior art date
Application number
PCT/US2001/049049
Other languages
English (en)
Other versions
WO2002050098A3 (fr
Inventor
Karyn M. Bieglecki
Amy Duda
Beena Koshy
Original Assignee
Genaissance Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Inc. filed Critical Genaissance Pharmaceuticals, Inc.
Priority to AU2002229099A priority Critical patent/AU2002229099A1/en
Publication of WO2002050098A2 publication Critical patent/WO2002050098A2/fr
Publication of WO2002050098A3 publication Critical patent/WO2002050098A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne de nouveaux variants génétiques du gène du récepteur de la prolactine (PRLR). La présente invention concerne plusieurs génotypes, haplotypes et paires d'haplotypes existant dans la population des Etats-Unis pour le gène du récepteur de la prolactine. La présente invention concerne également des compositions et des méthodes d'haplotypage et/ou de génotypage du gène du récepteur de la prolactine chez un individu. L'invention concerne également des polynucléotides définis par les haplotypes décrits ci-dessus.
PCT/US2001/049049 2000-12-18 2001-12-18 Haplotypes du gene du recepteur de la prolactine (prlr) WO2002050098A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002229099A AU2002229099A1 (en) 2000-12-18 2001-12-18 Haplotypes of the prlr gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25652300P 2000-12-18 2000-12-18
US60/256,523 2000-12-18

Publications (2)

Publication Number Publication Date
WO2002050098A2 true WO2002050098A2 (fr) 2002-06-27
WO2002050098A3 WO2002050098A3 (fr) 2003-03-20

Family

ID=22972544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/049049 WO2002050098A2 (fr) 2000-12-18 2001-12-18 Haplotypes du gene du recepteur de la prolactine (prlr)

Country Status (2)

Country Link
AU (1) AU2002229099A1 (fr)
WO (1) WO2002050098A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110585A2 (fr) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Genes lies au cancer (prlr)
US8263340B2 (en) * 2007-03-20 2012-09-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Constitutively active mutants of the prolactin receptor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GLASOW ET AL.: 'Mutational analysis of the PRL receptor gene in human breast tumors with differential PRL receptor protein expression' JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM vol. 86, no. 8, August 2001, pages 3826 - 3832, XP002958195 *
HU ET AL.: 'The human prolactin receptor gene structure and alternative promoter utilization: the generic promoter hPIII and a novel human promoter hPN' JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM vol. 84, no. 3, March 1999, pages 1153 - 1156, XP002958196 *
NICKERSON ET AL.: 'Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene' GENOME RESEARCH vol. 10, no. 10, October 2000, pages 1532 - 1545, XP002947337 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110585A2 (fr) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Genes lies au cancer (prlr)
WO2006110581A2 (fr) * 2005-04-07 2006-10-19 Novartis Vaccines And Diagnostics Inc. Genes associes au cancer
WO2006110585A3 (fr) * 2005-04-07 2006-12-21 Chiron Corp Genes lies au cancer (prlr)
WO2006110581A3 (fr) * 2005-04-07 2007-07-12 Novartis Vaccines & Diagnostic Genes associes au cancer
EP2083088A3 (fr) * 2005-04-07 2009-10-14 Novartis Vaccines and Diagnostics, Inc. Gènes associés au cancer
US8263340B2 (en) * 2007-03-20 2012-09-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Constitutively active mutants of the prolactin receptor

Also Published As

Publication number Publication date
AU2002229099A1 (en) 2002-07-01
WO2002050098A3 (fr) 2003-03-20

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