WO2002048713A3 - Identification of lead structures - Google Patents

Identification of lead structures Download PDF

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Publication number
WO2002048713A3
WO2002048713A3 PCT/EP2001/014808 EP0114808W WO0248713A3 WO 2002048713 A3 WO2002048713 A3 WO 2002048713A3 EP 0114808 W EP0114808 W EP 0114808W WO 0248713 A3 WO0248713 A3 WO 0248713A3
Authority
WO
WIPO (PCT)
Prior art keywords
identification
lead structures
structures
lead
relates
Prior art date
Application number
PCT/EP2001/014808
Other languages
French (fr)
Other versions
WO2002048713A2 (en
Inventor
Matthias Filter
Ulrich Rester
Li-Hsing Wang
Paul Wrede
Original Assignee
Callistogen Ag
Matthias Filter
Ulrich Rester
Li-Hsing Wang
Paul Wrede
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Callistogen Ag, Matthias Filter, Ulrich Rester, Li-Hsing Wang, Paul Wrede filed Critical Callistogen Ag
Priority to AU2002240837A priority Critical patent/AU2002240837A1/en
Publication of WO2002048713A2 publication Critical patent/WO2002048713A2/en
Publication of WO2002048713A3 publication Critical patent/WO2002048713A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • G16C20/64—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Library & Information Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Computing Systems (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Lead Frames For Integrated Circuits (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a method for identifying lead structures.
PCT/EP2001/014808 2000-12-15 2001-12-14 Identification of lead structures WO2002048713A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002240837A AU2002240837A1 (en) 2000-12-15 2001-12-14 Identification of lead structures

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25544600P 2000-12-15 2000-12-15
US60/255,446 2000-12-15

Publications (2)

Publication Number Publication Date
WO2002048713A2 WO2002048713A2 (en) 2002-06-20
WO2002048713A3 true WO2002048713A3 (en) 2004-02-19

Family

ID=22968368

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/014808 WO2002048713A2 (en) 2000-12-15 2001-12-14 Identification of lead structures

Country Status (2)

Country Link
AU (1) AU2002240837A1 (en)
WO (1) WO2002048713A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060200315A1 (en) * 2005-03-02 2006-09-07 Yingyao Zhou High-throughput screening hit selection system and method

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NISHIYAMA Y ET AL: "Low-molecular-weight anti-HIV-1 peptides from the amino-terminal sequence of rantes: possible lead compounds for coreceptor-directed anti-HIV-1 agents", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 9, no. 10, 17 May 1999 (1999-05-17), pages 1357 - 1360, XP004164891, ISSN: 0960-894X *
SCHWAB C H ET AL: "A SYSTEMATIC APPROACH TO FINDING NEW LEAD STRUCTURES HAVING BIOLOGICAL ACTIVITY", BIOINFORMATICS. GERMAN CONFERENCE ON BIOINFORMATICS, XX, XX, 30 September 1996 (1996-09-30), pages 166 - 177, XP000764931 *
WASZKOWYCZ, B. ET AL: "Large-scale virtual screening for discovering leads in the postgenomic era", IBM SYSTEMS JOURNAL, vol. 40, no. 2, - 2001, pages 360 - 376, XP002259024 *

Also Published As

Publication number Publication date
WO2002048713A2 (en) 2002-06-20
AU2002240837A1 (en) 2002-06-24

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