WO2002048173A3 - Expression of a cadherin-like protein in benign prostatic hyperplasia - Google Patents

Expression of a cadherin-like protein in benign prostatic hyperplasia Download PDF

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Publication number
WO2002048173A3
WO2002048173A3 PCT/US2001/047949 US0147949W WO0248173A3 WO 2002048173 A3 WO2002048173 A3 WO 2002048173A3 US 0147949 W US0147949 W US 0147949W WO 0248173 A3 WO0248173 A3 WO 0248173A3
Authority
WO
WIPO (PCT)
Prior art keywords
benign prostatic
prostatic hyperplasia
expression
cadherin
protein
Prior art date
Application number
PCT/US2001/047949
Other languages
French (fr)
Other versions
WO2002048173A2 (en
Inventor
William E Munger
Prakash Kulkarni
Robert H Getzenberg
Original Assignee
Gene Logic Inc
Japan Tobacco Inc
William E Munger
Prakash Kulkarni
Robert H Getzenberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gene Logic Inc, Japan Tobacco Inc, William E Munger, Prakash Kulkarni, Robert H Getzenberg filed Critical Gene Logic Inc
Priority to AU2002229004A priority Critical patent/AU2002229004A1/en
Publication of WO2002048173A2 publication Critical patent/WO2002048173A2/en
Publication of WO2002048173A3 publication Critical patent/WO2002048173A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates generally to the changes in gene expression in Benign Prostatic Hyperplasia (BPH). The invention relates specifically to a human gene family which is differentially expressed in BPH compared to normal prostate tissue.
PCT/US2001/047949 2000-12-13 2001-12-13 Expression of a cadherin-like protein in benign prostatic hyperplasia WO2002048173A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002229004A AU2002229004A1 (en) 2000-12-13 2001-12-13 Expression of a cadherin-like protein in benign prostatic hyperplasia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25492800P 2000-12-13 2000-12-13
US60/254,928 2000-12-13

Publications (2)

Publication Number Publication Date
WO2002048173A2 WO2002048173A2 (en) 2002-06-20
WO2002048173A3 true WO2002048173A3 (en) 2003-10-23

Family

ID=22966135

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047949 WO2002048173A2 (en) 2000-12-13 2001-12-13 Expression of a cadherin-like protein in benign prostatic hyperplasia

Country Status (2)

Country Link
AU (1) AU2002229004A1 (en)
WO (1) WO2002048173A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051514A1 (en) * 2000-01-07 2001-07-19 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001051514A1 (en) * 2000-01-07 2001-07-19 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
1995, WILEY & SONS INC., article AUSUBEL F.M. ET AL.: "Short protocols in molecular biology", pages: 15.3-5 - 16.58-62, XP002967111 *
DATABASE GENBANK [online] 12 September 2001 (2001-09-12), XP002967106, Database accession no. (AAD09283) *
DATABASE GENBANK [online] 12 September 2001 (2001-09-12), XP002967107, Database accession no. (AAE05293) *
DATABASE GENBANK [online] 22 February 2001 (2001-02-22), NAGASE T. ET AL.: "Homo sapians mRNA for KIAA1562 protein", XP002967108, Database accession no. (AB046782) *
DATABASE GENBANK [online] 24 February 2000 (2000-02-24), XP002967109, Database accession no. (AAA16643) *
DATABASE GENBANK [online] 24 February 2000 (2000-02-24), XP002967110, Database accession no. (AAY94923) *

Also Published As

Publication number Publication date
AU2002229004A1 (en) 2002-06-24
WO2002048173A2 (en) 2002-06-20

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