WO2002044718A3 - S.aureus protein staau r2, gene encoding it and uses thereof - Google Patents

S.aureus protein staau r2, gene encoding it and uses thereof Download PDF

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Publication number
WO2002044718A3
WO2002044718A3 PCT/CA2001/001754 CA0101754W WO0244718A3 WO 2002044718 A3 WO2002044718 A3 WO 2002044718A3 CA 0101754 W CA0101754 W CA 0101754W WO 0244718 A3 WO0244718 A3 WO 0244718A3
Authority
WO
WIPO (PCT)
Prior art keywords
relates
gene encoding
aureus protein
staau
aureus
Prior art date
Application number
PCT/CA2001/001754
Other languages
French (fr)
Other versions
WO2002044718A2 (en
Inventor
Jerry Pelletier
Philippe Gros
Michael Dubow
Original Assignee
Phagetech Inc
Jerry Pelletier
Philippe Gros
Michael Dubow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/727,892 external-priority patent/US20040091856A1/en
Application filed by Phagetech Inc, Jerry Pelletier, Philippe Gros, Michael Dubow filed Critical Phagetech Inc
Priority to CA002428595A priority Critical patent/CA2428595A1/en
Priority to AU2042202A priority patent/AU2042202A/en
Priority to JP2002546211A priority patent/JP2004522945A/en
Priority to AU2002220422A priority patent/AU2002220422B2/en
Priority to EP01998823A priority patent/EP1340079A2/en
Publication of WO2002044718A2 publication Critical patent/WO2002044718A2/en
Publication of WO2002044718A3 publication Critical patent/WO2002044718A3/en
Priority to US10/449,830 priority patent/US20040137516A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This invention relates to newly identified polynucleotides and polypeptides, and their production and uses, as well as their variants, agonists and antagonists, and their uses. In particular, the invention relates to specific interaction between the S. aureus STAAU_R2 related protein or specific regions thereof, and growth-inhibitory proteins encoded by the S. aureus bacteriophage genome. The invention relates to the use of these interaction target sites as the basis of drug screening assays.
PCT/CA2001/001754 1999-12-01 2001-11-30 S.aureus protein staau r2, gene encoding it and uses thereof WO2002044718A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002428595A CA2428595A1 (en) 2000-11-30 2001-11-30 Staphylococcus aureus protein staau_r2, gene encoding it and uses thereof
AU2042202A AU2042202A (en) 2000-12-01 2001-11-30 Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein staau r2
JP2002546211A JP2004522945A (en) 2000-12-01 2001-11-30 Compositions and methods related to the Staphylococcus aureus essential gene and its encoded protein STAAU_R2
AU2002220422A AU2002220422B2 (en) 2000-12-01 2001-11-30 S.aureus protein STAAU R2, gene encoding it and uses thereof
EP01998823A EP1340079A2 (en) 2000-11-30 2001-11-30 S. aureus protein staau-r2, gene encoding it and uses thereof
US10/449,830 US20040137516A1 (en) 1999-12-01 2003-05-31 DNA sequences from staphylococcus aureus bacteriophage 44AHJD that encode anti-microbial polypeptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/727,892 2000-11-30
US09/727,892 US20040091856A1 (en) 1999-12-01 2000-12-01 DNA sequences from staphylococcus aureus bacteriophage 44AHJD that encode anti-microbial polypeptides
US88556101A 2001-06-20 2001-06-20
US09/885,561 2001-06-20

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/449,830 Continuation US20040137516A1 (en) 1999-12-01 2003-05-31 DNA sequences from staphylococcus aureus bacteriophage 44AHJD that encode anti-microbial polypeptides

Publications (2)

Publication Number Publication Date
WO2002044718A2 WO2002044718A2 (en) 2002-06-06
WO2002044718A3 true WO2002044718A3 (en) 2002-12-12

Family

ID=27111604

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/001754 WO2002044718A2 (en) 1999-12-01 2001-11-30 S.aureus protein staau r2, gene encoding it and uses thereof

Country Status (5)

Country Link
EP (1) EP1340079A2 (en)
JP (1) JP2004522945A (en)
AU (2) AU2042202A (en)
CA (1) CA2428595A1 (en)
WO (1) WO2002044718A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116908265B (en) * 2023-09-11 2023-12-12 常州先趋医疗科技有限公司 Preparation method of electrochemical biosensor for detecting LAMP amplification products of nucleic acids

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032825A2 (en) * 1998-12-03 2000-06-08 Phagetech, Inc. Development of anti-microbial agents based on bacteriophage genomics
WO2001046383A2 (en) * 1999-12-22 2001-06-28 Phagetech, Inc. Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032825A2 (en) * 1998-12-03 2000-06-08 Phagetech, Inc. Development of anti-microbial agents based on bacteriophage genomics
WO2001046383A2 (en) * 1999-12-22 2001-06-28 Phagetech, Inc. Compositions and methods involving an essential staphylococcus aureus gene and its encoded protein

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALONSO J C ET AL: "NUCLEOTIDE SEQUENCE OF THE RECF GENE CLUSTER FROM STAPHYLOCOCCUS AUREUS AND COMPLEMENTATION ANALYSIS IN BACILLUS SUBTILIS RECF MUTANTS", MOLECULAR AND GENERAL GENETICS, SPRINGER VERLAG, BERLIN, DE, vol. 246, 1995, pages 680 - 686, XP002924864, ISSN: 0026-8925 *

Also Published As

Publication number Publication date
AU2002220422B9 (en) 2002-06-11
AU2002220422B2 (en) 2007-06-28
CA2428595A1 (en) 2002-06-06
JP2004522945A (en) 2004-07-29
AU2042202A (en) 2002-06-11
WO2002044718A2 (en) 2002-06-06
EP1340079A2 (en) 2003-09-03

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