WO2002044713A3 - Dispositif a flux traversant pour incubation et /ou hybridation bidimensionnelle sur supports solides - Google Patents

Dispositif a flux traversant pour incubation et /ou hybridation bidimensionnelle sur supports solides Download PDF

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Publication number
WO2002044713A3
WO2002044713A3 PCT/EP2001/014222 EP0114222W WO0244713A3 WO 2002044713 A3 WO2002044713 A3 WO 2002044713A3 EP 0114222 W EP0114222 W EP 0114222W WO 0244713 A3 WO0244713 A3 WO 0244713A3
Authority
WO
WIPO (PCT)
Prior art keywords
incubation
solid support
test fluid
disc
reservoir
Prior art date
Application number
PCT/EP2001/014222
Other languages
English (en)
Other versions
WO2002044713A2 (fr
Inventor
Fredericus Bernardu Thunnissen
F Nijpels
Original Assignee
Dot Diagnostics B V
Fredericus Bernardu Thunnissen
F Nijpels
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dot Diagnostics B V, Fredericus Bernardu Thunnissen, F Nijpels filed Critical Dot Diagnostics B V
Priority to AU2002220747A priority Critical patent/AU2002220747A1/en
Publication of WO2002044713A2 publication Critical patent/WO2002044713A2/fr
Publication of WO2002044713A3 publication Critical patent/WO2002044713A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/29—Mixing by periodically deforming flexible tubular members through which the material is flowing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/65—Mixers with shaking, oscillating, or vibrating mechanisms the materials to be mixed being directly submitted to a pulsating movement, e.g. by means of an oscillating piston or air column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des dispositifs à flux traversant pour incubation et/ou hybridation sur des supports solides. Un premier dispositif selon l'invention se compose comme suit: (a) support solide avec cible pour liaison ; (b) porte-support sur lequel (i) le support solide constitue l'une des parois matérialisant un espace d'incubation et qui comporte (ii) deux réservoirs situés de part et d'autre de l'espace d'incubation dont la fonction est, pour l'un, de permettre au liquide d'essai de pénétrer dans l'espace d'incubation, et pour l'autre de recueillir le liquide d'essai ; (c) dispositif générateur de pression pour le transfert du liquide d'essai d'un réservoir à l'autre ; (d) système de commande permettant d'acheminer le liquide d'un réservoir via la chambre d'incubation à l'autre réservoir et inversement, ce qui garantit une exposition répétée des composants du liquide d'essai aux composants présents sur le support solide. Un second dispositif selon l'invention se compose comme suit : (a) support solide renfermant une cible pour liaison ; (b) paroi du porte-support faisant face au support solide, dont une partie se compose d'un ou de plusieurs disques rotatifs ; (c) système mécanique réglant la rotation des disques ; (d) dispositif commandant le débit d'entrée du liquide d'essai et la rotation des disques. L'invention concerne également des ensembles dans lesquels sont combinés deux ou plus des dispositifs ci-dessus.
PCT/EP2001/014222 2000-11-30 2001-11-30 Dispositif a flux traversant pour incubation et /ou hybridation bidimensionnelle sur supports solides WO2002044713A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002220747A AU2002220747A1 (en) 2000-11-30 2001-11-30 Flow through device for two dimensional incubation and/or hybridization on solid supports

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00204277 2000-11-30
NL00204277.8 2000-11-30

Publications (2)

Publication Number Publication Date
WO2002044713A2 WO2002044713A2 (fr) 2002-06-06
WO2002044713A3 true WO2002044713A3 (fr) 2002-09-19

Family

ID=8172365

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/014222 WO2002044713A2 (fr) 2000-11-30 2001-11-30 Dispositif a flux traversant pour incubation et /ou hybridation bidimensionnelle sur supports solides

Country Status (2)

Country Link
AU (1) AU2002220747A1 (fr)
WO (1) WO2002044713A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6913931B2 (en) 2002-10-03 2005-07-05 3M Innovative Properties Company Devices, methods and systems for low volume microarray processing

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4726889A (en) * 1986-02-04 1988-02-23 Oncor, Inc. Process and apparatus for conducting electrophoresis and transfer
US5188963A (en) * 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
US5382511A (en) * 1988-08-02 1995-01-17 Gene Tec Corporation Method for studying nucleic acids within immobilized specimens
WO2001054814A2 (fr) * 2000-01-26 2001-08-02 Motorola, Inc. Compositions et procedes de realisation de reactions biologiques

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4726889A (en) * 1986-02-04 1988-02-23 Oncor, Inc. Process and apparatus for conducting electrophoresis and transfer
US5382511A (en) * 1988-08-02 1995-01-17 Gene Tec Corporation Method for studying nucleic acids within immobilized specimens
US5188963A (en) * 1989-11-17 1993-02-23 Gene Tec Corporation Device for processing biological specimens for analysis of nucleic acids
WO2001054814A2 (fr) * 2000-01-26 2001-08-02 Motorola, Inc. Compositions et procedes de realisation de reactions biologiques

Also Published As

Publication number Publication date
WO2002044713A2 (fr) 2002-06-06
AU2002220747A1 (en) 2002-06-11

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