WO2002044689A8 - Storing microparticles in optical switch which is transported by micro-fluidic device - Google Patents

Storing microparticles in optical switch which is transported by micro-fluidic device

Info

Publication number
WO2002044689A8
WO2002044689A8 PCT/US2001/045058 US0145058W WO0244689A8 WO 2002044689 A8 WO2002044689 A8 WO 2002044689A8 US 0145058 W US0145058 W US 0145058W WO 0244689 A8 WO0244689 A8 WO 0244689A8
Authority
WO
WIPO (PCT)
Prior art keywords
storing
microfluidic channels
microparticles
transported
micro
Prior art date
Application number
PCT/US2001/045058
Other languages
French (fr)
Other versions
WO2002044689A2 (en
WO2002044689A3 (en
Inventor
Mark Wang
Erhan Ata
Sadik Esener
Original Assignee
Univ California
Mark Wang
Erhan Ata
Sadik Esener
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Mark Wang, Erhan Ata, Sadik Esener filed Critical Univ California
Priority to EP01990768A priority Critical patent/EP1352093A4/en
Priority to AU3053002A priority patent/AU3053002A/en
Priority to AU2002230530A priority patent/AU2002230530B2/en
Priority to JP2002546188A priority patent/JP2004528156A/en
Publication of WO2002044689A2 publication Critical patent/WO2002044689A2/en
Publication of WO2002044689A8 publication Critical patent/WO2002044689A8/en
Publication of WO2002044689A3 publication Critical patent/WO2002044689A3/en

Links

Classifications

    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/04—Acceleration by electromagnetic wave pressure

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The invention contemplates the use of optical beams, as generate photonic pressure, or radiation pressure, to perform switching of small particles that are flowing in microfluidic channels. Small particles (1), for example 5 um diameter water microspheres or cells, within and moving with, a fluid (2), normally water, that is flowing within microfluidic channels (3) within a radiation transparent substrate (4) being pushed with optical pressure forces with a laser light switching beam (5), preferably as arises from VCSELs operating in Laguerre-Gaussian mode, at branching junctions such as an 'X' in the microfluidic channels (3) so as to enter into selected downstream branches OUTPUT 1 & 2, thereby realizing switching and storing of particles (1) including parallel.
PCT/US2001/045058 2000-11-28 2001-11-28 Storing microparticles in optical switch which is transported by micro-fluidic device WO2002044689A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01990768A EP1352093A4 (en) 2000-11-28 2001-11-28 Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
AU3053002A AU3053002A (en) 2000-11-28 2001-11-28 Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
AU2002230530A AU2002230530B2 (en) 2000-11-28 2001-11-28 Storing microparticles in optical switch which is transported by micro-fluidic device
JP2002546188A JP2004528156A (en) 2000-11-28 2001-11-28 Optical switching and photoselection of biological samples and microparticles transported in microfluidic devices, including integrated biochip devices

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99801200A 2000-11-28 2000-11-28
US25364400P 2000-11-28 2000-11-28
US60/253,644 2000-11-28
US09/998,012 2001-11-28

Publications (3)

Publication Number Publication Date
WO2002044689A2 WO2002044689A2 (en) 2002-06-06
WO2002044689A8 true WO2002044689A8 (en) 2002-11-14
WO2002044689A3 WO2002044689A3 (en) 2003-04-24

Family

ID=26943442

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045058 WO2002044689A2 (en) 2000-11-28 2001-11-28 Storing microparticles in optical switch which is transported by micro-fluidic device

Country Status (1)

Country Link
WO (1) WO2002044689A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8986966B2 (en) 2002-09-27 2015-03-24 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US9174222B2 (en) 2005-04-05 2015-11-03 The General Hospital Corporation Devices and method for enrichment and alteration of cells and other particles
US9487812B2 (en) 2012-02-17 2016-11-08 Colorado School Of Mines Optical alignment deformation spectroscopy

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030007894A1 (en) * 2001-04-27 2003-01-09 Genoptix Methods and apparatus for use of optical forces for identification, characterization and/or sorting of particles
DE60236159D1 (en) * 2001-07-13 2010-06-10 Caliper Life Sciences Inc METHOD FOR SEPARATING COMPONENTS OF A MIXTURE
US20050164181A1 (en) * 2001-11-27 2005-07-28 Thomas Bricson Nanostructure, in particular for analysing individual molecules
AU2003216175A1 (en) 2002-02-04 2003-09-02 Colorado School Of Mines Laminar flow-based separations of colloidal and cellular particles
EP1499453B1 (en) * 2002-04-17 2016-01-06 Cytonome/ST, LLC Apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
CA2536360C (en) * 2003-08-28 2013-08-06 Celula, Inc. Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network
KR100519672B1 (en) 2003-12-22 2005-10-11 주식회사 디지탈바이오테크놀러지 Channel Apparatus for Focusing a Fluid Flow
JP2007529203A (en) * 2004-03-12 2007-10-25 ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア Integrated cell manipulation and measurement method and apparatus
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US9885644B2 (en) 2006-01-10 2018-02-06 Colorado School Of Mines Dynamic viscoelasticity as a rapid single-cell biomarker
US9878326B2 (en) 2007-09-26 2018-01-30 Colorado School Of Mines Fiber-focused diode-bar optical trapping for microfluidic manipulation
US10722250B2 (en) 2007-09-04 2020-07-28 Colorado School Of Mines Magnetic-field driven colloidal microbots, methods for forming and using the same
FR2931141B1 (en) 2008-05-13 2011-07-01 Commissariat Energie Atomique MICROFLUIDIC SYSTEM AND METHOD FOR THE SORTING OF AMAS FROM CELLS AND PREFERENCE FOR CONTINUOUS ENCAPSULATION THROUGH THEIR SORTING
DE102008060332B4 (en) * 2008-12-03 2013-01-10 Albert-Ludwigs-Universität Freiburg Method for sorting at least one particle with a microfluidic sorting device with optical tweezers
CN101726483B (en) * 2009-12-28 2012-02-29 茅涵斌 Molecular imprinting, laser tweezers and microfluidic detection method and detector for chemical substances
DE102010036082B4 (en) 2010-08-26 2015-07-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Microfluidic measurement setup and optical analysis method for optical analysis of cells
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
CN111474106B (en) * 2019-01-23 2025-02-11 香港科技大学 Method and system for determining mechanical properties of biological cells or biological cell-like particles
US11318471B2 (en) * 2019-01-23 2022-05-03 The Hong Kong University Of Science And Technology Method and system for optofluidic stretching of biological cells and soft particles
CN112461830B (en) * 2020-11-05 2022-09-06 山东建筑大学 A small optical tweezers device and application of combined transparent medium microspheres

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055702A1 (en) * 2000-01-31 2001-08-02 Board Of Regents, The University Of Texas System Portable sensor array system
CA2425476C (en) * 2000-10-10 2011-02-01 Biotrove, Inc. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8986966B2 (en) 2002-09-27 2015-03-24 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
US9174222B2 (en) 2005-04-05 2015-11-03 The General Hospital Corporation Devices and method for enrichment and alteration of cells and other particles
US9487812B2 (en) 2012-02-17 2016-11-08 Colorado School Of Mines Optical alignment deformation spectroscopy

Also Published As

Publication number Publication date
WO2002044689A2 (en) 2002-06-06
WO2002044689A3 (en) 2003-04-24

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