WO2002042460A3 - Compositions et procedes associes a des genes et a des proteines specifiques du colon - Google Patents

Compositions et procedes associes a des genes et a des proteines specifiques du colon Download PDF

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Publication number
WO2002042460A3
WO2002042460A3 PCT/US2001/043611 US0143611W WO0242460A3 WO 2002042460 A3 WO2002042460 A3 WO 2002042460A3 US 0143611 W US0143611 W US 0143611W WO 0242460 A3 WO0242460 A3 WO 0242460A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
compositions
antagonists
colon
nucleic acids
Prior art date
Application number
PCT/US2001/043611
Other languages
English (en)
Other versions
WO2002042460A2 (fr
Inventor
Roberto A Macina
Herve Recipon
Jason Pluta
Malavika G Ghosh
Yongming Sun
Chenghua Liu
Original Assignee
Diadexus Inc
Roberto A Macina
Herve Recipon
Jason Pluta
Malavika G Ghosh
Yongming Sun
Chenghua Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diadexus Inc, Roberto A Macina, Herve Recipon, Jason Pluta, Malavika G Ghosh, Yongming Sun, Chenghua Liu filed Critical Diadexus Inc
Priority to AU2002219819A priority Critical patent/AU2002219819A1/en
Publication of WO2002042460A2 publication Critical patent/WO2002042460A2/fr
Publication of WO2002042460A3 publication Critical patent/WO2002042460A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des acides nucléiques et des polypeptides récemment identifiés, présents dans des cellules de côlon normal et néoplasique, y compris des fragments, des variantes génétiques et des dérivés de ces acides nucléiques et polypeptides. L'invention a également trait à des anticorps dirigés contre les polypeptides de l'invention, et à des agonistes et antagonistes de ces polypeptides ; à des compositions contenant les acides nucléiques, polypeptides, anticorps, variantes génétiques, dérivés, agonistes et antagonistes de l'invention et à des procédés d'utilisation de ces compositions. Par utilisation, on entend l'identification, le diagnostic, la surveillance, la stadification, l'imagerie et le traitement du cancer du côlon et d'états pathologiques non cancéreux de tissu du côlon, l'identification de tissu du côlon, la surveillance et l'identification et/ou la conception d'agonistes et d'antagonistes desdits polypeptides. Les utilisations incluent également la thérapie génique, la production d'animaux et de cellules transgéniques ainsi que la production de tissu de côlon mis au point génétiquement à des fins de traitement et de recherche.
PCT/US2001/043611 2000-11-22 2001-11-21 Compositions et procedes associes a des genes et a des proteines specifiques du colon WO2002042460A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002219819A AU2002219819A1 (en) 2000-11-22 2001-11-21 Compositions and methods relating to colon specific genes and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25250500P 2000-11-22 2000-11-22
US60/252,505 2000-11-22

Publications (2)

Publication Number Publication Date
WO2002042460A2 WO2002042460A2 (fr) 2002-05-30
WO2002042460A3 true WO2002042460A3 (fr) 2003-05-01

Family

ID=22956289

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/043611 WO2002042460A2 (fr) 2000-11-22 2001-11-21 Compositions et procedes associes a des genes et a des proteines specifiques du colon

Country Status (3)

Country Link
US (1) US20020164344A1 (fr)
AU (1) AU2002219819A1 (fr)
WO (1) WO2002042460A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007224012A (ja) * 2006-01-30 2007-09-06 Fujifilm Corp 酵素架橋したタンパク質ナノ粒子
WO2019208659A1 (fr) * 2018-04-26 2019-10-31 栄研化学株式会社 Dispositif d'examen d'échantillon de selles, et procédé d'examen d'échantillon de selles

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039419A1 (fr) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Genes et proteines specifiques du colon
WO2000007632A1 (fr) * 1998-08-04 2000-02-17 Diadexus Llc Nouveau procede de diagnostic, de surveillance, de classification par stades, d'imagerie et de traitement du cancer du colon

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039419A1 (fr) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Genes et proteines specifiques du colon
WO2000007632A1 (fr) * 1998-08-04 2000-02-17 Diadexus Llc Nouveau procede de diagnostic, de surveillance, de classification par stades, d'imagerie et de traitement du cancer du colon

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 September 1999 (1999-09-01), B. BIRREN ET AL: "Homo sapiens chromosome 3 clone RP11-107G13 map 3, working DRAFT SEQUENCE, 48 unordered pieces", XP002219973, retrieved from EBI, HINXTON, UK Database accession no. AC009760 *
DATABASE EMBL [online] 23 March 2000 (2000-03-23), D.M. MUZNY ET AL: "Homo sapiens 3 BAC RP11-362A9 (Roswell park cancer institute human BAC library complete sequence", XP002219972, retrieved from EBI, HINXTON,UK Database accession no. AC026347 *
DATABASE EMBL [online] B. LOFTUS ET AL: "ENTDD85TF Entamoeba histolytica sheared DNA Entamoeba histolytica genomic, DNA sequence", XP002219974, retrieved from EBI, HINXTON, UK Database accession no. AZ548245 *
DATABASE EMBL [online] M.D. ADAMS ET AL: "CIT-HSP-2324H7.TR CIT-HSP Homo sapiens genomic clone 2324H7, genomic survey sequence", XP002219971, retrieved from EBI, HINXTON, UK Database accession no. AQ035542 *
UNPUBLISHED *

Also Published As

Publication number Publication date
US20020164344A1 (en) 2002-11-07
AU2002219819A1 (en) 2002-06-03
WO2002042460A2 (fr) 2002-05-30

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