WO2002040668A3 - Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen - Google Patents

Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen Download PDF

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Publication number
WO2002040668A3
WO2002040668A3 PCT/EP2001/012545 EP0112545W WO0240668A3 WO 2002040668 A3 WO2002040668 A3 WO 2002040668A3 EP 0112545 W EP0112545 W EP 0112545W WO 0240668 A3 WO0240668 A3 WO 0240668A3
Authority
WO
WIPO (PCT)
Prior art keywords
dna sequences
proteins
gene products
treating inflammations
sequences underlying
Prior art date
Application number
PCT/EP2001/012545
Other languages
English (en)
French (fr)
Other versions
WO2002040668A2 (de
Inventor
Juerg Tschopp
Fabio Martinon
Original Assignee
Apoxis Sa
Juerg Tschopp
Fabio Martinon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10059595A external-priority patent/DE10059595A1/de
Application filed by Apoxis Sa, Juerg Tschopp, Fabio Martinon filed Critical Apoxis Sa
Priority to AU2002218269A priority Critical patent/AU2002218269A1/en
Priority to US10/416,935 priority patent/US20040053292A1/en
Priority to EP01996605A priority patent/EP1349933A2/de
Publication of WO2002040668A2 publication Critical patent/WO2002040668A2/de
Publication of WO2002040668A3 publication Critical patent/WO2002040668A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Die vorliegende Erfindung betrifft DNA-Sequenzen, die für mindestens eine PYD-Domäne codieren, Expressionsvektoren, die derartige DNA-Sequenzen enthalten, Wirtszellen, die mit derartigen Expressionsvektoren transformiert sind, aufgereinigte Genprodukte der vorgenannten DNA-Sequenzen, Antikörper gegen für vorgenannten Genprodukte, sowie Verfahren zur Isolierung und/oder zur Expression der vorgenannten Genprodukte. Darüber hinaus betrifft die vorliegende Erfindung die Verwendung der vorgenannten DNA-Sequenzen oder von deren Genprodukten zur Behandlung von Entzündungsereignissen.
PCT/EP2001/012545 2000-11-15 2001-10-30 Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen WO2002040668A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002218269A AU2002218269A1 (en) 2000-11-15 2001-10-30 Proteins and dna sequences underlying these proteins used for treating inflammations
US10/416,935 US20040053292A1 (en) 2000-11-15 2001-10-30 Proteins and dna sequences underlying these proteins used for treating inflammations
EP01996605A EP1349933A2 (de) 2000-11-15 2001-10-30 Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10056687 2000-11-15
DE10056687.1 2000-11-15
DE10059595.2 2000-11-30
DE10059595A DE10059595A1 (de) 2000-11-15 2000-11-30 Proteine und den Proteinen zugrundeliegende DNA-Sequenzen mit Funktion bei Entzündungsereignissen

Publications (2)

Publication Number Publication Date
WO2002040668A2 WO2002040668A2 (de) 2002-05-23
WO2002040668A3 true WO2002040668A3 (de) 2003-07-03

Family

ID=26007674

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012545 WO2002040668A2 (de) 2000-11-15 2001-10-30 Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen

Country Status (4)

Country Link
US (1) US20040053292A1 (de)
EP (1) EP1349933A2 (de)
AU (1) AU2002218269A1 (de)
WO (1) WO2002040668A2 (de)

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WO2002040668A2 (de) * 2000-11-15 2002-05-23 Apoxis Sa Proteine und den proteinen zugrundeliegende dna-sequenzen mit funktion bei entzündungsereignissen
AU2002243234A1 (en) * 2000-11-15 2002-06-24 Incyte Genomics, Inc. Embryogenesis associated proteins
US6949363B2 (en) 2000-12-22 2005-09-27 Brilstol-Myers Squibb Polynucleotides encoding novel human leucine-rich repeat containing protein expressed predominately in bone marrow, HLRRBM1
EP1409673B1 (de) 2000-12-22 2006-06-07 Brystol-Myers Squibb Company Menschliches leucinereiche wiederholungen enthaltendes protein, vorwiegend im dünndarm exprimiert, hlrrsi1
US7160695B2 (en) 2001-01-31 2007-01-09 Wyeth Molecules of the PYRIN/NBS/LRR protein family and uses thereof
US7041643B2 (en) 2001-01-31 2006-05-09 Millennium Pharmaceuticals, Inc. Molecules of the PYRIN/NBS/LRR protein family and uses thereof
DE10139874A1 (de) * 2001-08-10 2003-04-30 Schering Ag Humane Mater-Proteine
US20040002593A1 (en) * 2002-04-04 2004-01-01 Reed John C. PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use
US20030224438A1 (en) * 2002-05-24 2003-12-04 Millennium Pharmaceuticals, Inc. Novel molecules of the PYRIN/NBS/LRR protein family and uses thereof
WO2006110591A2 (en) * 2005-04-07 2006-10-19 University Of South Florida POP2 NFkB-INHIBITING POLYPEPTIDES, NUCLEIC ACIDS AND METHODS OF USE
WO2008066483A1 (en) * 2006-11-27 2008-06-05 Mohammad Alimohammadi Use of nalp5 in methods for diagnosis and therapy of parathyroid related disorders
US8685400B2 (en) * 2007-07-30 2014-04-01 University Of Miami Modulating inflammasome activity and inflammation in the central nervous system
GB0724735D0 (en) * 2007-12-19 2008-01-30 Psynova Neurotech Ltd Methods and biomarkers for diagnosing and monitoring psychotic disorders
GB0818660D0 (en) * 2008-10-10 2008-11-19 Cambridge Entpr Ltd Biomarkers
CN106011233A (zh) * 2010-08-13 2016-10-12 莫尔豪斯医学院 中风的生物标记
GB201021502D0 (en) 2010-12-20 2011-02-02 Cambridge Entpr Ltd Biomarkers
CA2821651A1 (en) 2010-12-20 2012-06-28 Cambridge Enterprise Limited Biomarkers
GB201404189D0 (en) 2014-03-10 2014-04-23 Cambridge Entpr Ltd Novel biomarkers
GB201411037D0 (en) * 2014-06-20 2014-08-06 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL)

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WO2000070047A2 (en) * 1999-05-14 2000-11-23 Incyte Genomics, Inc. Full-length molecules expressed in human tissues

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WO1999047669A2 (de) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Menschliche nukleinsäuresequenzen aus brusttumorgewebe
WO2000070047A2 (en) * 1999-05-14 2000-11-23 Incyte Genomics, Inc. Full-length molecules expressed in human tissues

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Title
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Also Published As

Publication number Publication date
WO2002040668A2 (de) 2002-05-23
EP1349933A2 (de) 2003-10-08
AU2002218269A1 (en) 2002-05-27
US20040053292A1 (en) 2004-03-18

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