WO2002039990A3 - Method for screening anti-proliferative compounds and inhibiting tumor growth - Google Patents
Method for screening anti-proliferative compounds and inhibiting tumor growth Download PDFInfo
- Publication number
- WO2002039990A3 WO2002039990A3 PCT/EP2001/013076 EP0113076W WO0239990A3 WO 2002039990 A3 WO2002039990 A3 WO 2002039990A3 EP 0113076 W EP0113076 W EP 0113076W WO 0239990 A3 WO0239990 A3 WO 0239990A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tumor growth
- inhibiting tumor
- screening anti
- proliferative compounds
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
- G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002542365A JP2004514122A (en) | 2000-11-14 | 2001-11-12 | Methods for screening antiproliferative compounds and inhibiting tumor growth |
EP01996369A EP1337854A2 (en) | 2000-11-14 | 2001-11-12 | Method for screening anti-proliferative compounds and inhibiting tumor growth |
AU2002217020A AU2002217020A1 (en) | 2000-11-14 | 2001-11-12 | Method for screening anti-proliferative compounds and inhibiting tumor growth |
US10/416,669 US20040048318A1 (en) | 2000-11-14 | 2001-12-11 | Method for screening anti-proliferative compounds and method for inhibiting tumor growth |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24848900P | 2000-11-14 | 2000-11-14 | |
US60/248,489 | 2000-11-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002039990A2 WO2002039990A2 (en) | 2002-05-23 |
WO2002039990A3 true WO2002039990A3 (en) | 2003-03-13 |
Family
ID=22939368
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2001/013076 WO2002039990A2 (en) | 2000-11-14 | 2001-11-12 | Method for screening anti-proliferative compounds and inhibiting tumor growth |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1337854A2 (en) |
JP (1) | JP2004514122A (en) |
AU (1) | AU2002217020A1 (en) |
WO (1) | WO2002039990A2 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006528611A (en) * | 2003-07-25 | 2006-12-21 | ノバルティス アクチエンゲゼルシャフト | Substituted lactams and their use as anticancer agents |
US7153846B2 (en) | 2003-10-24 | 2006-12-26 | Sanofi-Aventis Deutschland Gmbh | Bengamide derivatives, process for preparing them, and their use |
FR2878528B1 (en) * | 2004-11-29 | 2008-05-16 | Aventis Pharma Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2878525B1 (en) | 2004-11-29 | 2007-02-23 | Aventis Pharma Sa | BENGAMIDES HAVING SUBSTITUTED CAPROLACTAM CYCLE, PREPARATION METHOD, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901555A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZOTHIAZEPINE, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901556A1 (en) | 2006-05-24 | 2007-11-30 | Sanofi Aventis Sa | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE DERIVATIVES, THEIR PREPARATION, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2901554B1 (en) | 2006-05-24 | 2011-04-01 | Sanofi Aventis | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINE, PREPARATION THEREOF, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
FR2926463B1 (en) * | 2008-01-22 | 2010-08-13 | Centre Nat Rech Scient | USE OF AMINOPEPTIDASE INHIBITORS OR AZAINDOLE COMPOUNDS FOR PREVENTING OR TREATING CANCER METASTASES OF EPITHELIAL ORIGIN |
AU2009313167C1 (en) * | 2008-11-06 | 2014-06-12 | Merck Patent Gmbh | Use of EEF1A as biomarker for screening of MetAP2 inhibitors |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998056372A1 (en) * | 1997-06-09 | 1998-12-17 | Massachusetts Institute Of Technology | TYPE 2 METHIONINE AMINOPEPTIDASE (MetAP2) INHIBITORS AND USES THEROF |
-
2001
- 2001-11-12 WO PCT/EP2001/013076 patent/WO2002039990A2/en not_active Application Discontinuation
- 2001-11-12 JP JP2002542365A patent/JP2004514122A/en active Pending
- 2001-11-12 AU AU2002217020A patent/AU2002217020A1/en not_active Abandoned
- 2001-11-12 EP EP01996369A patent/EP1337854A2/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998056372A1 (en) * | 1997-06-09 | 1998-12-17 | Massachusetts Institute Of Technology | TYPE 2 METHIONINE AMINOPEPTIDASE (MetAP2) INHIBITORS AND USES THEROF |
Non-Patent Citations (3)
Title |
---|
MARTIN H ET AL: "ANTIBODIES AGAINST THE MAJOR BRAIN ISOFORMS OF 14-3-3 PROTEIN AN ANTIBODY SPECIFIC FOR THE N-ACETYLATED AMINO-TERMINUS OF A PROTEIN", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 331, no. 3, 1 October 1993 (1993-10-01), pages 296 - 303, XP002063495, ISSN: 0014-5793 * |
PIETROMONACO S F ET AL: "Association of 14-3-3 proteins with centrosomes.", BLOOD CELLS, MOLECULES & DISEASES. UNITED STATES 1996, vol. 22, no. 3, 1996, pages 225 - 237, XP002222680, ISSN: 1079-9796 * |
YAFFE M B ET AL: "The structural basis for 14-3-3: phosphopeptide binding specificity", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 91, no. 7, 26 December 1997 (1997-12-26), pages 961 - 971, XP002090547, ISSN: 0092-8674 * |
Also Published As
Publication number | Publication date |
---|---|
AU2002217020A1 (en) | 2002-05-27 |
JP2004514122A (en) | 2004-05-13 |
WO2002039990A2 (en) | 2002-05-23 |
EP1337854A2 (en) | 2003-08-27 |
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