WO2002039873A3 - System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same - Google Patents

System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same Download PDF

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Publication number
WO2002039873A3
WO2002039873A3 PCT/IL2001/001044 IL0101044W WO0239873A3 WO 2002039873 A3 WO2002039873 A3 WO 2002039873A3 IL 0101044 W IL0101044 W IL 0101044W WO 0239873 A3 WO0239873 A3 WO 0239873A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxygen saturation
difference map
functional brain
map algorithm
saturation difference
Prior art date
Application number
PCT/IL2001/001044
Other languages
French (fr)
Other versions
WO2002039873A2 (en
Inventor
Amir Gil
Tamir Gil
Eli Horn
Yuval Garini
Original Assignee
Applied Spectral Imaging Ltd
Amir Gil
Tamir Gil
Eli Horn
Yuval Garini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2000/000781 external-priority patent/WO2001037717A2/en
Application filed by Applied Spectral Imaging Ltd, Amir Gil, Tamir Gil, Eli Horn, Yuval Garini filed Critical Applied Spectral Imaging Ltd
Priority to AU2002223989A priority Critical patent/AU2002223989A1/en
Publication of WO2002039873A2 publication Critical patent/WO2002039873A2/en
Publication of WO2002039873A3 publication Critical patent/WO2002039873A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14553—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain

Abstract

A method of functional brain mapping of a subject is disclosed. The method is effected by (a) illuminating an exposed cortex of a brain or portion thereof of the subject with incident light (Fig. 6); (b) acquiring a reflectance spectrum of each picture element of at least a portion of the exposed cortex of the subject (Fig. 5).
PCT/IL2001/001044 2000-11-14 2001-11-11 System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same WO2002039873A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002223989A AU2002223989A1 (en) 2000-11-14 2001-11-11 System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US71152100A 2000-11-14 2000-11-14
US09/711,521 2000-11-14
PCT/IL2000/000781 WO2001037717A2 (en) 1999-11-26 2000-11-23 System and method for functional brain mapping
ILPCT/IL00/00781 2000-11-23
US09/776,871 2001-02-06
US09/776,871 US20020099295A1 (en) 1999-11-26 2001-02-06 System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same

Publications (2)

Publication Number Publication Date
WO2002039873A2 WO2002039873A2 (en) 2002-05-23
WO2002039873A3 true WO2002039873A3 (en) 2002-08-29

Family

ID=27270620

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/001044 WO2002039873A2 (en) 2000-11-14 2001-11-11 System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same

Country Status (2)

Country Link
AU (1) AU2002223989A1 (en)
WO (1) WO2002039873A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007063626A1 (en) * 2007-04-19 2009-09-10 Carl Zeiss Surgical Gmbh Method and apparatus for displaying a field of a brain of a patient and navigation system for brain operations
US9125606B2 (en) * 2013-03-13 2015-09-08 Koninklijke Philips N.V. Device and method for determining the blood oxygen saturation of a subject
RU2697752C2 (en) * 2018-04-24 2019-08-19 Олег Юрьевич Титов Electrode for functional mapping of hidden cortical formations (versions)
WO2019226664A1 (en) * 2018-05-21 2019-11-28 Rowan University Noninvasive three-dimensional fluorescence microscopy for skin disease detection

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015969A (en) * 1996-09-16 2000-01-18 The Regents Of The University Of California Multiple-wavelength spectroscopic quantitation of light-absorbing species in scattering media
US6088099A (en) * 1996-10-30 2000-07-11 Applied Spectral Imaging Ltd. Method for interferometer based spectral imaging of moving objects

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015969A (en) * 1996-09-16 2000-01-18 The Regents Of The University Of California Multiple-wavelength spectroscopic quantitation of light-absorbing species in scattering media
US6088099A (en) * 1996-10-30 2000-07-11 Applied Spectral Imaging Ltd. Method for interferometer based spectral imaging of moving objects

Also Published As

Publication number Publication date
WO2002039873A2 (en) 2002-05-23
AU2002223989A1 (en) 2002-05-27

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