WO2002036552A8 - Aminoalcohol derivatives and their use as beta 3 adrenergic agonists - Google Patents

Aminoalcohol derivatives and their use as beta 3 adrenergic agonists

Info

Publication number
WO2002036552A8
WO2002036552A8 PCT/JP2001/009461 JP0109461W WO0236552A8 WO 2002036552 A8 WO2002036552 A8 WO 2002036552A8 JP 0109461 W JP0109461 W JP 0109461W WO 0236552 A8 WO0236552 A8 WO 0236552A8
Authority
WO
WIPO (PCT)
Prior art keywords
beta
adrenergic agonists
aminoalcohol derivatives
hydrogen
compound
Prior art date
Application number
PCT/JP2001/009461
Other languages
French (fr)
Other versions
WO2002036552A1 (en
Inventor
Naoaki Fujii
Kiyoshi Taniguchi
Hiroshi Kayakiri
Kazuyoshi Nozaki
Naoko Tanimura
Nobuhiro Yamamoto
Hirofumi Ishikawa
Kaori Hamada
Original Assignee
Fujisawa Pharmaceutical Co
Naoaki Fujii
Kiyoshi Taniguchi
Hiroshi Kayakiri
Kazuyoshi Nozaki
Naoko Tanimura
Nobuhiro Yamamoto
Hirofumi Ishikawa
Kaori Hamada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co, Naoaki Fujii, Kiyoshi Taniguchi, Hiroshi Kayakiri, Kazuyoshi Nozaki, Naoko Tanimura, Nobuhiro Yamamoto, Hirofumi Ishikawa, Kaori Hamada filed Critical Fujisawa Pharmaceutical Co
Publication of WO2002036552A1 publication Critical patent/WO2002036552A1/en
Publication of WO2002036552A8 publication Critical patent/WO2002036552A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

The present invention relates to a compound of formula (I) wherein R1 is hydrogen or a hydroxy protective group, R2 is hydrogen or an amino protective group, R3 is lower alkoxycarbonylamino, and R4 is lower alkoxycarbonylamino, or a salt thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.
PCT/JP2001/009461 2000-11-02 2001-10-26 Aminoalcohol derivatives and their use as beta 3 adrenergic agonists WO2002036552A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPR1204A AUPR120400A0 (en) 2000-11-02 2000-11-02 New compound
AUPR1204 2000-11-02

Publications (2)

Publication Number Publication Date
WO2002036552A1 WO2002036552A1 (en) 2002-05-10
WO2002036552A8 true WO2002036552A8 (en) 2002-07-18

Family

ID=3825247

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2001/009461 WO2002036552A1 (en) 2000-11-02 2001-10-26 Aminoalcohol derivatives and their use as beta 3 adrenergic agonists

Country Status (2)

Country Link
AU (1) AUPR120400A0 (en)
WO (1) WO2002036552A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5070797B2 (en) * 2005-12-08 2012-11-14 Ｊｎｃ株式会社 Lateral oxirane compound and polymer thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2179286A5 (en) * 1972-04-05 1973-11-16 Honeywell Bull
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
AUPP549998A0 (en) * 1998-08-26 1998-09-17 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPQ575300A0 (en) * 2000-02-21 2000-03-16 Fujisawa Pharmaceutical Co., Ltd. New compound

Also Published As

Publication number Publication date
AUPR120400A0 (en) 2000-11-23
WO2002036552A1 (en) 2002-05-10

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