WO2002024743A3 - 55063, a human nmda family member and uses thereof - Google Patents

55063, a human nmda family member and uses thereof Download PDF

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Publication number
WO2002024743A3
WO2002024743A3 PCT/US2001/029870 US0129870W WO0224743A3 WO 2002024743 A3 WO2002024743 A3 WO 2002024743A3 US 0129870 W US0129870 W US 0129870W WO 0224743 A3 WO0224743 A3 WO 0224743A3
Authority
WO
WIPO (PCT)
Prior art keywords
hnmda
nucleic acid
acid molecules
molecules
expression vectors
Prior art date
Application number
PCT/US2001/029870
Other languages
French (fr)
Other versions
WO2002024743A2 (en
Inventor
Rory A J Curtis
Original Assignee
Millennium Pharm Inc
Rory A J Curtis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rory A J Curtis filed Critical Millennium Pharm Inc
Priority to EP01971324A priority Critical patent/EP1332213A2/en
Priority to AU2001291221A priority patent/AU2001291221A1/en
Publication of WO2002024743A2 publication Critical patent/WO2002024743A2/en
Publication of WO2002024743A3 publication Critical patent/WO2002024743A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated HNMDA-1 nucleic acid molecules, which encode novel glutamate-gated ion channel family molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing HNMDA-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an HNMDA-1 gene has been introduced or disrupted. The invention still further provides isolated HNMDA-1 polypeptides, fusion polypeptides, antigenic peptides and anti-HNMDA-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/029870 2000-09-19 2001-09-19 55063, a human nmda family member and uses thereof WO2002024743A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01971324A EP1332213A2 (en) 2000-09-19 2001-09-19 55063, a human nmda family member and uses thereof
AU2001291221A AU2001291221A1 (en) 2000-09-19 2001-09-19 55063, a human nmda family member and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23353700P 2000-09-19 2000-09-19
US60/233,537 2000-09-19

Publications (2)

Publication Number Publication Date
WO2002024743A2 WO2002024743A2 (en) 2002-03-28
WO2002024743A3 true WO2002024743A3 (en) 2003-05-22

Family

ID=22877644

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/029870 WO2002024743A2 (en) 2000-09-19 2001-09-19 55063, a human nmda family member and uses thereof

Country Status (4)

Country Link
US (1) US20020123098A1 (en)
EP (1) EP1332213A2 (en)
AU (1) AU2001291221A1 (en)
WO (1) WO2002024743A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002064628A2 (en) * 2001-02-13 2002-08-22 Pe Corporation (Ny) Isolated human transporter proteins nucleic acids and use thereof
JPWO2003037930A1 (en) * 2001-10-29 2005-02-17 財団法人かずさディー・エヌ・エー研究所 Novel human N-methyl-D-aspartate (NMDA) glutamate receptor polypeptide and gene encoding the same
WO2011035045A1 (en) * 2009-09-17 2011-03-24 The Regents Of The University Of California Ion channel compositions and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081413A2 (en) * 2000-04-27 2001-11-01 Pe Corporation (Ny) Isolated human transporter proteins, nucleic acids and uses thereof
WO2002012340A2 (en) * 2000-08-03 2002-02-14 Incyte Genomics, Inc. Transporters and ion channels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001081413A2 (en) * 2000-04-27 2001-11-01 Pe Corporation (Ny) Isolated human transporter proteins, nucleic acids and uses thereof
WO2002012340A2 (en) * 2000-08-03 2002-02-14 Incyte Genomics, Inc. Transporters and ion channels

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CIABARRA A.M. ET AL.: "Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic Glutamate receptor family", JOURNAL OF NEUROSCIENCE, vol. 15, no. 10, October 1995 (1995-10-01), pages 6498 - 6508, XP001061257, ISSN: 0270-6474 *
DATABASE EMBL [online] 16 December 1999 (1999-12-16), "Homo sapiens cDNA clone IMAGE:2190570 3' similar to TR:Q62800 IONOTROPIC GLUTAMATE RECEPTOR", XP002204849, Database accession no. AI613310 *
DATABASE EMBL [online] 21 June 2000 (2000-06-21), "Homo sapiens clone EUROIMAGE 2190570", XP002204848, Database accession no. AL359651 *
DATABASE EMBL [online] 7 June 2000 (2000-06-07), "EST368285 MAGE resequences, MAGD Homo sapiens cDNA, mRNA sequence.", XP002204847, Database accession no. AW956215 *
See also references of EP1332213A2 *
SUCHER N.J. ET AL.: "Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain", JOURNAL OF NEUROSCIENCE, vol. 15, no. 10, October 1995 (1995-10-01), pages 6509 - 6520, XP001061256, ISSN: 0270-6474 *

Also Published As

Publication number Publication date
US20020123098A1 (en) 2002-09-05
WO2002024743A2 (en) 2002-03-28
AU2001291221A1 (en) 2002-04-02
EP1332213A2 (en) 2003-08-06

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