WO2002022195A2 - Container for inhalation anesthetic - Google Patents
Container for inhalation anesthetic Download PDFInfo
- Publication number
- WO2002022195A2 WO2002022195A2 PCT/US2001/028550 US0128550W WO0222195A2 WO 2002022195 A2 WO2002022195 A2 WO 2002022195A2 US 0128550 W US0128550 W US 0128550W WO 0222195 A2 WO0222195 A2 WO 0222195A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- container
- anesthetic
- inhalation anesthetic
- pharmaceutical product
- containers
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/18—Vaporising devices for anaesthetic preparations
- A61M16/183—Filling systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Definitions
- the present invention relates to containers for liquid inhalation anesthetics, more particularly, to aluminum containers that are suitable for storing halogenated inhalation anesthetics.
- Containers such as those of the present invention, are used to store the liquid anesthetic agent, and to dispense it to a device for administering the agent to a patient.
- vaporizers' which mate with the container, receive the liquid anesthetic through an orifice in the container, vaporize the anesthetic, mix it with oxygen and optionally other gases, and mete out the gaseous mixture to the patient.
- Inhalation anesthetics have traditionally been stored in glass containers. These containers, however, possess certain drawbacks. Glass requires careful handling to avoid breakage, and when breakage does occur, product is lost and injury may occur. In addition, it has been theorized that the inhalation anesthetic may react with components of the glass, leading to certain degradation products. C.f. US Patent No. 5,990,176.
- plastic containers for inhalation anesthetics made of certain plastics have been proposed. C.f. WO 99/34762, US Patent Nos. 6,074,668 and 6,162,443 and US Patent Application Publication No. US 2001/0000729 Al . While plastic containers are less likely to break than glass containers, they are still susceptible to breakage under common use conditions. Moreover, many plastics tend to be vapor permeable, allowing the inhalation anesthetic to escape the container and ambient vapors to enter the container over time, leading to possible contamination. Also, plastic containers are subject to deformation when exposed to elevated temperatures, which may be required during processing and treatment of the inhalation anesthetic-containing containers. Moreover, inhalation anesthetics have strong organic solvent properties, which typically will dissolve and/or react with the plastic material, leading to measurable impurities in the inhalation anesthetic.
- Containers for sevoflurane have also been made of stainless steel.
- US Patent No. 5,990,176 describes a container made of glass, plastic or stainless steel for holding sevoflurane.
- Metal containers have been used for various types of pharmaceutical products, as well as food and beverages.
- US Patent No. 6,008,273 describes an epoxy resin for coating the inside of a metal container for use as a food or beverage container.
- the present invention overcomes the drawbacks of the prior art by providing a pharmaceutical product comprising a halogenated inhalation anesthetic stored within an aluminum container. It has been found that aluminum containers provide structural integrity, inertness and vapor-barrier properties that are well-suited for storage and handling of such inhalation anesthetics. In addition, aluminum is light in weight, resistant to heat-deformation, easily recycled and protects the inhalation anesthetic from light-induced degradation.
- the container is provided with an orifice for filling or removing the halogenated inhalation anesthetic, and a closure for the orifice.
- the closure preferably has a lining that helps the closure retain the desirable characteristics of the aluminum container.
- the closure may be provided with a valve assembly for regulating the flow of anesthetic.
- the closure may also be provided with indexing elements specially configured and unique to the particular inhalation anesthetic housed in the container to help ensure the anesthetic is administered only by the vaporizer for which it is designed.
- the aluminum container may also be provided with a lining for added inertness.
- the container will be bottle-shaped.
- Halogenated inhalation anesthetics are well known and commercially available. These include sevoflurane (fluoromethyl-2,2,2-trifluoro/l/(tri- fluoromethyl)ethyl ether), desflurane (2-difluromethyl 1,2,2,2-tetrafluoroethyl ether), isoflurane (l-chloro-2,2,2-trifluoroethyl difluoromethyl ether), enflurane (2-chloro-l,l,2-trifluoroethyl difluoromethyl ether), methoxyflurane (2,2-dichloro-l,l-difluoroethyl methyl ether) and halothane (2-bromo-2- chloro-l,l,l-trifluoroethane), all of which are liquids at ambient conditions.
- Aluminum containers suitable for use in the present invention are commercially available. Typically, they will be manufactured in the size and shape of the glass containers in which inhalation anesthetics are currently commercially sold. Commercially sold containers are bottle-shaped, i.e. they are outfitted with a neck whose mouth (orifice) can be sealed shut with a closure.
- the aluminum containers of the present invention may be lined or unlined. Although the prior art hypothesizes that aluminum oxide present in glass containers may lead to degradation of the inhalation anesthetic, it has been found that no such degradation problem arises in the present invention. However, in some cases it may be desirable to provide the aluminum container with an inert lining to prevent the formation or release of flakes or small particles of aluminum during the manufacture of the container and formation of threads on the neck of the container. These flakes, while not a problem from a safety standpoint, may appear in the liquid anesthetic and be unpleasing from a cosmetic or visual standpoint. Therefore, it is desirable to prevent formation of particles or flakes during the bottle manufacturing process.
- Suitable lining materials are those which demonstrate no significant solubility in the inhalation anesthetic, i.e. do not render the inhalation anesthetic unusable. These lining materials include lacquers and enamels, and preferably contain an epoxyphenolic resin. Examples of lining materials that are commercially available include Type Nos. 7407P and 7940 HL/F from HOBA
- 7407P is a highly flexible liner suitable for aluminum containers having a thickness of 8-14 microns, and is based upon epoxyphenolic resin having a solid content of about 30 parts by weight, a delivered viscosity of about 90 sec. DIN 4 mm 20 °C, a density of about 0.99 g/ml.
- the thickness of the liner may be less for certain applications.
- the containers of the present invention will have an orifice for filling or removing the halogenated inhalation anesthetic, as well as a closure for the orifice.
- the closure should be chosen so as not to compromise the characteristics of the container, namely, it should provide structural integrity, inertness and vapor barrier properties.
- the closure will typically be a cap, such as those used on commercially available glass containers.
- the cap may be screw-on, snap-on or of a more elaborate design for fitting with commercially available vaporizers which are used to dispense the inhalation anesthetics.
- the closure may be made of aluminum or other metal, or of a polymer material.
- closures that are lined with the aforementioned lacquers, or with a polytetrafluoroethylene (PTFE).
- PTFE polytetrafluoroethylene
- One such lining is commercially available under the name "Plytrax 100" and has a PTFE facing with a polyethylene foam backing, available from Norton Performance
- valve assembly means a closure provided with at least one valve for regulating flow of the anesthetic.
- valve assemblies serve to, alternately, close the orifice of the container to minimize loss of anesthetic from the container, and open the orifice by way of interaction with the vaporizer to deliver anesthetic to the vaporizer.
- valve assemblies may be screwed or snapped onto the container.
- closures may be provided with indexing elements that allow the container to mate only with a vaporizer having corresponding indexing elements. This helps to ensure that an anesthetic is administered only through the vaporizer for which it was designed.
- the container is bottle-shaped, whose neck
- valve is sealed closed with a cap or valve assembly.
- the neck may be threaded, to allow screw-on of the cap or valve assembly.
- the valve assembly may be provided with indexing elements having a configuration that is unique and specific to the particular inhalation anesthetic stored in the container. The indexing elements helps assure that the container storing a particular inhalation anesthetic will only mate to a vaporizer designed for that inhalation anesthetic.
- the container size and shape may be varied to indicate a particular type of inhalation anesthetic as well as to avoid mistaken mixing of different types of anesthetics in a vaporizer.
- Various alloys of aluminum may be used for the container, and still fall within the scope of the present invention.
- the container may be a bottle sized container for holding the final drug product, or may be in a larger tank or drum size for use during shipping, mixing or holding of the inhalation anesthetic in the bulk drug fo ⁇ n or in a crude manufactured form awaiting final distillation.
- the aluminum may be in the form of a liner or inner layer of another type of container, such as a plastic or steel container.
Landscapes
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
Abstract
Description
Claims
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2420035A CA2420035C (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
BRPI0113917-7A BR0113917B1 (en) | 2000-09-15 | 2001-09-13 | A pharmaceutical product comprising a halogenated inhalation anesthetic contained in an aluminum container. |
JP2002526441A JP5801024B2 (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
EP01970882A EP1317301B1 (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
KR1020037003733A KR100881241B1 (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
AT01970882T ATE297779T1 (en) | 2000-09-15 | 2001-09-13 | CONTAINER FOR INHALATION ANESTHETIC PRODUCTS |
MXPA03002340A MXPA03002340A (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic. |
AU9083301A AU9083301A (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
DE60111546T DE60111546T2 (en) | 2000-09-15 | 2001-09-13 | CONTAINER FOR INHALATION CLEANER |
AU2001290833A AU2001290833B2 (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23330200P | 2000-09-15 | 2000-09-15 | |
US60/233,302 | 2000-09-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002022195A2 true WO2002022195A2 (en) | 2002-03-21 |
WO2002022195A3 WO2002022195A3 (en) | 2002-08-08 |
Family
ID=22876707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/028550 WO2002022195A2 (en) | 2000-09-15 | 2001-09-13 | Container for inhalation anesthetic |
Country Status (17)
Country | Link |
---|---|
US (3) | US8001961B2 (en) |
EP (1) | EP1317301B1 (en) |
JP (2) | JP5801024B2 (en) |
KR (2) | KR100881241B1 (en) |
CN (1) | CN1228103C (en) |
AR (2) | AR031873A1 (en) |
AT (1) | ATE297779T1 (en) |
AU (2) | AU2001290833B2 (en) |
BR (1) | BR0113917B1 (en) |
CA (1) | CA2420035C (en) |
DE (1) | DE60111546T2 (en) |
ES (1) | ES2244656T3 (en) |
MX (1) | MXPA03002340A (en) |
PT (1) | PT1317301E (en) |
TW (1) | TW523409B (en) |
WO (1) | WO2002022195A2 (en) |
ZA (1) | ZA200301153B (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008048947A2 (en) * | 2006-10-16 | 2008-04-24 | Abbott Laboratories | Apparatus for and related method of inhibiting lewis acid degradation in a vaporizer |
NL2018046A (en) * | 2016-11-02 | 2017-01-19 | Central Glass Co Ltd | Method for washing sevoflurane storage container and method for storing sevoflurane |
WO2017011867A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
WO2017011866A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
WO2017011865A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
RU2685412C2 (en) * | 2016-11-02 | 2019-04-18 | Сентрал Гласс Компани, Лимитед | Method for washing sevoflurane container and method for storing sevoflurane |
CN111053760A (en) * | 2019-12-27 | 2020-04-24 | 江苏恒丰强生物技术有限公司 | Inhalation sevoflurane for pets |
US11571526B2 (en) | 2016-09-06 | 2023-02-07 | Medical Developments International Limited | Inhaler device for inhalable liquids |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW523409B (en) * | 2000-09-15 | 2003-03-11 | Baxter Int | Container for inhalation anesthetic |
US9278048B2 (en) * | 2009-05-06 | 2016-03-08 | Baxter International, Inc. | Pharmaceutical product and method of use |
CA2921743A1 (en) * | 2013-08-19 | 2015-02-26 | Klaus Michael SCHMIDT | Non-anesthetic protective gases in combination with liquid anesthetic agents for organ protection |
UY37974A (en) | 2017-11-20 | 2019-06-28 | Lanxess Deutschland Gmbh | ALUMINUM GLASSES CONTAINING DICARBONIC DIESTERS |
KR102200764B1 (en) | 2020-02-18 | 2021-01-08 | 가톨릭대학교 산학협력단 | Anesthesia container pressing device attached on anesthesia vaporizer |
AU2023232562A1 (en) | 2022-03-08 | 2024-09-05 | Equashield Medical Ltd | Fluid transfer station in a robotic pharmaceutical preparation system |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4250334A (en) | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
US5505236A (en) | 1994-04-04 | 1996-04-09 | Abbott Laboratories | Anesthetic vaporizer filling system |
US5679576A (en) | 1994-04-08 | 1997-10-21 | Central Glass Co., Ltd. | Gas chromatographic analysis of fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether |
WO1999034762A1 (en) | 1998-01-09 | 1999-07-15 | Abbott Laboratories | Container for an inhalation anesthetic |
US5990176A (en) | 1997-01-27 | 1999-11-23 | Abbott Laboratories | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid |
US6074668A (en) | 1998-01-09 | 2000-06-13 | Abbott Laboratories | Container for an inhalation anesthetic |
US6083514A (en) | 1998-01-09 | 2000-07-04 | Abbott Laboratories | Polymethylpentene container for an inhalation anesthetic |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE515475A (en) * | 1951-11-13 | |||
JPH01283225A (en) * | 1988-05-10 | 1989-11-14 | Toyo Jozo Co Ltd | Aerosol preparation for treating infectious disease of bovine respiratory organ and treating method using the same |
JPH0267374A (en) * | 1988-08-31 | 1990-03-07 | Takeuchi Press Ind Co Ltd | Aerosol container |
US5617906A (en) | 1991-01-24 | 1997-04-08 | The Boc Group Plc | Container for anaesthetic agent |
US6596260B1 (en) * | 1993-08-27 | 2003-07-22 | Novartis Corporation | Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol |
JP2780616B2 (en) * | 1993-11-22 | 1998-07-30 | 東洋製罐株式会社 | Epoxy paint |
GB9504265D0 (en) * | 1995-03-03 | 1995-04-19 | Medeva Plc | Corticosteroid-containing pharmaceutical composition |
ES2276736T3 (en) * | 1995-04-14 | 2007-07-01 | Smithkline Beecham Corporation | DOSE METER INHALER FOR FLUCTICASONE PROPIONATE. |
GB9517998D0 (en) * | 1995-09-04 | 1995-11-08 | Bioglan Lab Ltd | Compositions and device for their administration |
DE19709704C2 (en) * | 1997-03-10 | 1999-11-04 | Michael Georgieff | Use of a liquid preparation of xenon for intravenous administration when inducing and / or maintaining anesthesia |
US6008273A (en) | 1997-05-09 | 1999-12-28 | The Dexter Corporation | Waterborne coating compositions for metal containers |
JP4498480B2 (en) * | 1997-12-10 | 2010-07-07 | 千寿製薬株式会社 | Nasal formulation |
US6045784A (en) * | 1998-05-07 | 2000-04-04 | The Procter & Gamble Company | Aerosol package compositions containing fluorinated hydrocarbon propellants |
US6315985B1 (en) * | 1999-06-18 | 2001-11-13 | 3M Innovative Properties Company | C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability |
TW523409B (en) * | 2000-09-15 | 2003-03-11 | Baxter Int | Container for inhalation anesthetic |
-
2001
- 2001-09-10 TW TW090122371A patent/TW523409B/en not_active IP Right Cessation
- 2001-09-13 BR BRPI0113917-7A patent/BR0113917B1/en not_active IP Right Cessation
- 2001-09-13 DE DE60111546T patent/DE60111546T2/en not_active Expired - Lifetime
- 2001-09-13 WO PCT/US2001/028550 patent/WO2002022195A2/en active IP Right Grant
- 2001-09-13 ES ES01970882T patent/ES2244656T3/en not_active Expired - Lifetime
- 2001-09-13 AU AU2001290833A patent/AU2001290833B2/en not_active Expired
- 2001-09-13 CN CNB018151116A patent/CN1228103C/en not_active Expired - Lifetime
- 2001-09-13 US US09/952,039 patent/US8001961B2/en active Active
- 2001-09-13 AT AT01970882T patent/ATE297779T1/en active
- 2001-09-13 CA CA2420035A patent/CA2420035C/en not_active Expired - Fee Related
- 2001-09-13 MX MXPA03002340A patent/MXPA03002340A/en active IP Right Grant
- 2001-09-13 JP JP2002526441A patent/JP5801024B2/en not_active Expired - Lifetime
- 2001-09-13 PT PT01970882T patent/PT1317301E/en unknown
- 2001-09-13 KR KR1020037003733A patent/KR100881241B1/en active IP Right Grant
- 2001-09-13 AU AU9083301A patent/AU9083301A/en active Pending
- 2001-09-13 KR KR1020087015131A patent/KR100901049B1/en active IP Right Grant
- 2001-09-13 EP EP01970882A patent/EP1317301B1/en not_active Expired - Lifetime
- 2001-09-14 AR ARP010104375A patent/AR031873A1/en not_active Application Discontinuation
-
2003
- 2003-02-12 ZA ZA200301153A patent/ZA200301153B/en unknown
-
2011
- 2011-08-02 US US13/196,884 patent/US20110284418A1/en not_active Abandoned
- 2011-11-14 JP JP2011249097A patent/JP5746002B2/en not_active Expired - Lifetime
-
2014
- 2014-11-25 AR ARP140104408A patent/AR100298A2/en unknown
-
2019
- 2019-01-18 US US16/252,341 patent/US20190151600A1/en not_active Abandoned
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4250334A (en) | 1979-12-26 | 1981-02-10 | Baxter Travenol Laboratories, Inc. | Method of synthesizing fluoromethylhexafluoroisopropyl ether |
US5505236A (en) | 1994-04-04 | 1996-04-09 | Abbott Laboratories | Anesthetic vaporizer filling system |
US5679576A (en) | 1994-04-08 | 1997-10-21 | Central Glass Co., Ltd. | Gas chromatographic analysis of fluoromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether |
US5990176A (en) | 1997-01-27 | 1999-11-23 | Abbott Laboratories | Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid |
WO1999034762A1 (en) | 1998-01-09 | 1999-07-15 | Abbott Laboratories | Container for an inhalation anesthetic |
US6074668A (en) | 1998-01-09 | 2000-06-13 | Abbott Laboratories | Container for an inhalation anesthetic |
US6083514A (en) | 1998-01-09 | 2000-07-04 | Abbott Laboratories | Polymethylpentene container for an inhalation anesthetic |
US6162443A (en) | 1998-01-09 | 2000-12-19 | Abbott Laboratories | Container for an inhalation anesthetic |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008048947A2 (en) * | 2006-10-16 | 2008-04-24 | Abbott Laboratories | Apparatus for and related method of inhibiting lewis acid degradation in a vaporizer |
WO2008048947A3 (en) * | 2006-10-16 | 2008-11-13 | Abbott Lab | Apparatus for and related method of inhibiting lewis acid degradation in a vaporizer |
WO2017011867A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
WO2017011866A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
WO2017011865A1 (en) | 2015-07-20 | 2017-01-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
US11672925B2 (en) | 2015-07-20 | 2023-06-13 | Medical Developments International Limited | Inhaler device for inhalable liquids |
US11571526B2 (en) | 2016-09-06 | 2023-02-07 | Medical Developments International Limited | Inhaler device for inhalable liquids |
NL2018046A (en) * | 2016-11-02 | 2017-01-19 | Central Glass Co Ltd | Method for washing sevoflurane storage container and method for storing sevoflurane |
BE1024432B1 (en) * | 2016-11-02 | 2018-02-19 | Central Glass Company, Limited | METHOD FOR WASHING OF SEVOFLURAN STORAGE CONTAINER AND METHOD FOR STORAGE OF SEVOFLURAN |
EP3318340A1 (en) * | 2016-11-02 | 2018-05-09 | Central Glass Company, Limited | Method for washing sevoflurane storage container and method for storing sevoflurane |
RU2685412C2 (en) * | 2016-11-02 | 2019-04-18 | Сентрал Гласс Компани, Лимитед | Method for washing sevoflurane container and method for storing sevoflurane |
CN111053760A (en) * | 2019-12-27 | 2020-04-24 | 江苏恒丰强生物技术有限公司 | Inhalation sevoflurane for pets |
Also Published As
Publication number | Publication date |
---|---|
US20190151600A1 (en) | 2019-05-23 |
BR0113917A (en) | 2003-07-22 |
EP1317301B1 (en) | 2005-06-15 |
CN1228103C (en) | 2005-11-23 |
JP2012030119A (en) | 2012-02-16 |
CN1452501A (en) | 2003-10-29 |
ES2244656T3 (en) | 2005-12-16 |
ZA200301153B (en) | 2004-01-23 |
ATE297779T1 (en) | 2005-07-15 |
US20110284418A1 (en) | 2011-11-24 |
KR20030030001A (en) | 2003-04-16 |
US20020068767A1 (en) | 2002-06-06 |
MXPA03002340A (en) | 2003-06-06 |
AR031873A1 (en) | 2003-10-08 |
KR20080070080A (en) | 2008-07-29 |
JP2004508146A (en) | 2004-03-18 |
WO2002022195A3 (en) | 2002-08-08 |
AR100298A2 (en) | 2016-09-28 |
CA2420035A1 (en) | 2002-03-21 |
AU2001290833B2 (en) | 2006-02-02 |
DE60111546D1 (en) | 2005-07-21 |
DE60111546T2 (en) | 2006-05-11 |
KR100881241B1 (en) | 2009-02-05 |
KR100901049B1 (en) | 2009-06-04 |
JP5746002B2 (en) | 2015-07-08 |
CA2420035C (en) | 2010-02-16 |
PT1317301E (en) | 2005-08-31 |
JP5801024B2 (en) | 2015-10-28 |
TW523409B (en) | 2003-03-11 |
AU9083301A (en) | 2002-03-26 |
US8001961B2 (en) | 2011-08-23 |
BR0113917B1 (en) | 2010-12-28 |
EP1317301A2 (en) | 2003-06-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20190151600A1 (en) | Container For Inhalation Anesthetic | |
AU2001290833A1 (en) | Container for inhalation anesthetic | |
US6162443A (en) | Container for an inhalation anesthetic | |
RU2720158C2 (en) | Inhaler device for inhalation liquids | |
EP2427163B1 (en) | Pharmaceutical product and method of use | |
JP7043399B2 (en) | Inhaler device for inhalable liquids | |
US20070221217A1 (en) | Container for an inhalation anesthetic | |
WO2006019795A9 (en) | Container for an inhalation anesthetic |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 1200300196 Country of ref document: VN |
|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2001970882 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2001290833 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2003/01153 Country of ref document: ZA Ref document number: 200301153 Country of ref document: ZA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002526441 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2420035 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1-2003-500064 Country of ref document: PH |
|
WWE | Wipo information: entry into national phase |
Ref document number: 255/MUMNP/2003 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 018151116 Country of ref document: CN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 03021575 Country of ref document: CO |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020037003733 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/2003/002340 Country of ref document: MX |
|
WWP | Wipo information: published in national office |
Ref document number: 1020037003733 Country of ref document: KR |
|
WWP | Wipo information: published in national office |
Ref document number: 2001970882 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWG | Wipo information: grant in national office |
Ref document number: 2001970882 Country of ref document: EP |
|
WWG | Wipo information: grant in national office |
Ref document number: 2001290833 Country of ref document: AU |