WO2002020786A3 - Kinase d interacting protein - Google Patents

Kinase d interacting protein Download PDF

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Publication number
WO2002020786A3
WO2002020786A3 PCT/GB2001/003977 GB0103977W WO0220786A3 WO 2002020786 A3 WO2002020786 A3 WO 2002020786A3 GB 0103977 W GB0103977 W GB 0103977W WO 0220786 A3 WO0220786 A3 WO 0220786A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
kinase
interacting protein
fusions
polynucleotide
Prior art date
Application number
PCT/GB2001/003977
Other languages
French (fr)
Other versions
WO2002020786A2 (en
Inventor
Giampietro Schiavo
Teresa Iglesias
Original Assignee
Imp Cancer Res Tech
Giampietro Schiavo
Teresa Iglesias
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imp Cancer Res Tech, Giampietro Schiavo, Teresa Iglesias filed Critical Imp Cancer Res Tech
Priority to AU2001284272A priority Critical patent/AU2001284272A1/en
Publication of WO2002020786A2 publication Critical patent/WO2002020786A2/en
Publication of WO2002020786A3 publication Critical patent/WO2002020786A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A polynucleotide comprising a nucleotide sequence which encodes the polypeptide whose amino acid sequence is given in Figure (1b) or Figure (11) or a fragment or variant or fusion thereof or a fusion of said fragment or variant, or its complement, the polypeptide encoded by said polynucleotide and fragments or variants or fusions thereof, antibodies specifically binding the said polypeptide or fragments or variants or fusions thereof. The invention further comprises methods of producing said polypeptide and antibodies and uses thereof.
PCT/GB2001/003977 2000-09-06 2001-09-06 Kinase d interacting protein WO2002020786A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001284272A AU2001284272A1 (en) 2000-09-06 2001-09-06 Kinase d interacting protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23044900P 2000-09-06 2000-09-06
US60/230,449 2000-09-06

Publications (2)

Publication Number Publication Date
WO2002020786A2 WO2002020786A2 (en) 2002-03-14
WO2002020786A3 true WO2002020786A3 (en) 2002-08-29

Family

ID=22865263

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/003977 WO2002020786A2 (en) 2000-09-06 2001-09-06 Kinase d interacting protein

Country Status (2)

Country Link
AU (1) AU2001284272A1 (en)
WO (1) WO2002020786A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002230904A1 (en) * 2000-12-21 2002-07-01 New York University A transmembrane protein as a downstream target of neurotrophin and ephrin receptor tyrosine kinases, dna encoding same monoclonal antibodies thereto
CN106047862A (en) * 2016-06-07 2016-10-26 上海欧易生物医学科技有限公司 Reverse transcription method for reducing false negative rate of yeast two-hybrid cDNA library
CN116194138A (en) * 2020-08-07 2023-05-30 博德研究所 Phosphate dysregulation via XPR1: KIDINS220 protein complex in therapeutic targeting of cancer

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM [online] EMBL; 11 November 1999 (1999-11-11), OHARA ET AL.: "Homo sapiens mRNA for KIAA1250 protein, partial cds.", XP002196566, retrieved from EBI accession no. AB033076 Database accession no. AB033076 *
DATABASE SWALL [online] 1 May 2000 (2000-05-01), NAGASE ET AL.: "KIAA1250 protein (fragment)", XP002196567, retrieved from EBI accession no. Q9ULH0 Database accession no. Q9ULH0 *
GSCHWENDT ET AL.: "Regulation of protein kinase Cmu by basic peptides and heparin", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 33, 15 August 1997 (1997-08-15), pages 20742 - 20746, XP002196563 *
IGLESIAS ET AL.: "Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 51, 22 December 2000 (2000-12-22), pages 40048 - 40056, XP002196565 *
MATTHEWS ET AL.: "Characterization of serine 916 as an in vivo autophosporylation site for protein kinase D/protein kinase Cmu", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 37, 10 September 1999 (1999-09-10), pages 26543 - 26549, XP002196564 *
NAGASE ET AL.: "Prediction of the coding sequences of unidentified human genes ...", DNA RESEARCH, vol. 6, 1999, pages 337 - 345, XP002943288 *
NISHIKAWA K ET AL: "DETERMINATION OF THE SPECIFIC SUBSTRATE SEQUENCE MOTIFS OF PROTEIN KINASE C ISOZYMES", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 272, no. 2, 10 January 1997 (1997-01-10), pages 952 - 960, XP002925439, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
AU2001284272A1 (en) 2002-03-22
WO2002020786A2 (en) 2002-03-14

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