WO2002015894A3 - Use of vitamin d derivatives as bone resorption inhibitors - Google Patents

Use of vitamin d derivatives as bone resorption inhibitors Download PDF

Info

Publication number
WO2002015894A3
WO2002015894A3 PCT/US2001/022614 US0122614W WO0215894A3 WO 2002015894 A3 WO2002015894 A3 WO 2002015894A3 US 0122614 W US0122614 W US 0122614W WO 0215894 A3 WO0215894 A3 WO 0215894A3
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
bone resorption
derivatives
resorption inhibitors
bone
Prior art date
Application number
PCT/US2001/022614
Other languages
French (fr)
Other versions
WO2002015894A2 (en
Inventor
Seiichi Ishizuka
Kazuya Takenouchi
Atsushi Imaizumi
Yasuhiro Oue
Noriyoshi Kurihara
Sakamuri V Reddy
G David Roodman
Original Assignee
Teijin Ltd
Univ Texas Health
Seiichi Ishizuka
Kazuya Takenouchi
Atsushi Imaizumi
Yasuhiro Oue
Noriyoshi Kurihara
Sakamuri V Reddy
G David Roodman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd, Univ Texas Health, Seiichi Ishizuka, Kazuya Takenouchi, Atsushi Imaizumi, Yasuhiro Oue, Noriyoshi Kurihara, Sakamuri V Reddy, G David Roodman filed Critical Teijin Ltd
Priority to JP2002520815A priority Critical patent/JP2004528269A/en
Priority to AU2001284657A priority patent/AU2001284657B2/en
Priority to CA002420274A priority patent/CA2420274A1/en
Priority to NZ524305A priority patent/NZ524305A/en
Priority to EP01963731A priority patent/EP1311253A2/en
Priority to AU8465701A priority patent/AU8465701A/en
Priority to US10/362,565 priority patent/US20040019024A1/en
Publication of WO2002015894A2 publication Critical patent/WO2002015894A2/en
Publication of WO2002015894A3 publication Critical patent/WO2002015894A3/en
Priority to NO20030820A priority patent/NO20030820L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

To obtain a bone resorption inhibitor or a treating agent for Paget's disease of bone, there are provided a method of inhibiting bone resorption, comprising administering to a patient a vitamin D antagonist; and a method for treating Paget's disease of bone, comprising administering to a patient a vitamin D antagonist.
PCT/US2001/022614 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors WO2002015894A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2002520815A JP2004528269A (en) 2001-08-22 2001-08-22 Use of vitamin D derivatives as bone resorption inhibitors
AU2001284657A AU2001284657B2 (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors
CA002420274A CA2420274A1 (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors
NZ524305A NZ524305A (en) 2000-08-23 2001-08-22 Use of vitamin D derivatives as bone resorption inhibitors
EP01963731A EP1311253A2 (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors
AU8465701A AU8465701A (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors
US10/362,565 US20040019024A1 (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors
NO20030820A NO20030820L (en) 2000-08-23 2003-02-21 Use of vitamin D derivatives as bone resorption inhibitors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000-252177 2000-08-23
JP2000252177A JP2002069003A (en) 2000-08-23 2000-08-23 Deossification inhibitor containing vitamin d derivative

Publications (2)

Publication Number Publication Date
WO2002015894A2 WO2002015894A2 (en) 2002-02-28
WO2002015894A3 true WO2002015894A3 (en) 2002-08-29

Family

ID=18741464

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022614 WO2002015894A2 (en) 2000-08-23 2001-08-22 Use of vitamin d derivatives as bone resorption inhibitors

Country Status (7)

Country Link
EP (1) EP1311253A2 (en)
JP (1) JP2002069003A (en)
AU (2) AU8465701A (en)
CA (1) CA2420274A1 (en)
NO (1) NO20030820L (en)
NZ (1) NZ524305A (en)
WO (1) WO2002015894A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2476679A1 (en) * 2002-02-20 2003-08-28 Teijin Limited Vitamin d3 derivatives and remedies using the same
EP1342796A3 (en) * 2002-02-22 2004-01-02 Teijin Limited Compound for the treatment of paget's disease of bone
WO2004067525A1 (en) 2003-01-30 2004-08-12 Teijin Pharma Limited Vitamin d3 lactone derivative
CN100506793C (en) * 2003-11-04 2009-07-01 帝人制药株式会社 Vitamin D* lactam derivative
US7524980B2 (en) 2003-11-04 2009-04-28 Teijin Pharma Limited Vitamin D3 lactam derivative
JP2007070281A (en) * 2005-09-06 2007-03-22 Matsumoto Shika Univ Remedy for osteoporosis produced by using retinoid x receptor-relating compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093519A (en) * 1988-05-04 1992-03-03 Ire-Medgenix S.A. Vitamin d derivatives: therapeutic applications and applications to assays of metabolities of vitamin d
DE19744127A1 (en) * 1997-10-01 1999-04-15 Schering Ag New vitamin D derivatives with cyclopropyl rings in the side chains, processes and intermediates for their manufacture and their use in the manufacture of pharmaceuticals
WO2000024712A1 (en) * 1998-10-23 2000-05-04 Teijin Limited Vitamin d3 derivatives and remedies for inflammatory respiratory diseases containing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093519A (en) * 1988-05-04 1992-03-03 Ire-Medgenix S.A. Vitamin d derivatives: therapeutic applications and applications to assays of metabolities of vitamin d
DE19744127A1 (en) * 1997-10-01 1999-04-15 Schering Ag New vitamin D derivatives with cyclopropyl rings in the side chains, processes and intermediates for their manufacture and their use in the manufacture of pharmaceuticals
WO2000024712A1 (en) * 1998-10-23 2000-05-04 Teijin Limited Vitamin d3 derivatives and remedies for inflammatory respiratory diseases containing the same

Also Published As

Publication number Publication date
AU2001284657B2 (en) 2006-01-19
CA2420274A1 (en) 2002-02-28
NZ524305A (en) 2004-08-27
NO20030820D0 (en) 2003-02-21
EP1311253A2 (en) 2003-05-21
WO2002015894A2 (en) 2002-02-28
AU8465701A (en) 2002-03-04
NO20030820L (en) 2003-04-22
JP2002069003A (en) 2002-03-08

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